Gene Page: TERC
Summary ?
| GeneID | 7012 |
| Symbol | TERC |
| Synonyms | DKCA1|PFBMFT2|SCARNA19|TR|TRC3|hTR |
| Description | telomerase RNA component |
| Reference | MIM:602322|HGNC:HGNC:11727|Ensembl:ENSG00000270141|Ensembl:ENSG00000277925| |
| Gene type | ncRNA |
| Map location | 3q26 |
| Pascal p-value | 0.004 |
| eGene | Meta |
| Support | Chromatin Remodeling Genes |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AP003108.2 | 0.76 | 0.48 |
| LINGO3 | 0.76 | 0.70 |
| RGS14 | 0.75 | 0.78 |
| RGS9 | 0.74 | 0.21 |
| ADRA2C | 0.74 | 0.57 |
| TTC22 | 0.74 | 0.69 |
| TAC1 | 0.73 | 0.78 |
| PENK | 0.73 | 0.39 |
| DACT2 | 0.72 | 0.17 |
| LRPAP1 | 0.72 | 0.72 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| EMX1 | -0.23 | -0.18 |
| ZNF238 | -0.23 | -0.20 |
| DPP4 | -0.23 | -0.20 |
| MPPED1 | -0.23 | -0.17 |
| CBS | -0.23 | -0.36 |
| NEUROD6 | -0.22 | -0.22 |
| CCDC90A | -0.22 | -0.37 |
| NEUROD2 | -0.22 | -0.22 |
| SLA | -0.22 | -0.15 |
| DACT1 | -0.22 | -0.20 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |