Gene Page: TNNT2

Summary
GeneID  7139
Symbol  TNNT2
Synonyms  CMH2|CMPD2|MGC3889|TnTC|cTnT
Description  troponin T type 2 (cardiac)
See related  HGNC:11949|MIM:191045|Ensembl:ENSG00000118194|HPRD:01844|
Locus tag  -
Gene type  protein-coding
Map location  1q32
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
ExpressionExpressionP value: 1.609 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CUGBP20.950.97
RC3H20.950.97
AFF40.950.96
KIF1B0.950.96
DYRK1A0.950.96
MARCH60.940.96
NCOA30.940.95
TANC20.940.96
PUM20.940.96
MED130.940.95
Top 10 negatively co-expressed genes
FXYD1-0.74-0.85
AF347015.31-0.73-0.84
MT-CO2-0.73-0.85
HSD17B14-0.72-0.78
HIGD1B-0.72-0.86
AF347015.33-0.70-0.80
AIFM3-0.70-0.74
TSC22D4-0.70-0.76
MT-CYB-0.70-0.80
IFI27-0.70-0.81
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003779actin bindingIDA8205619 
GO:0005523tropomyosin bindingIDA10850966 
GO:0030172troponin C bindingIPI8205619 |15542288 
GO:0031013troponin I bindingIPI15542288 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0055010ventricular cardiac muscle morphogenesisIMP16754800 
GO:0008016regulation of heart contractionIMP15542288 
GO:0032780negative regulation of ATPase activityIDA10850966 
GO:0032781positive regulation of ATPase activityIDA10850966 |12186860 
GO:0030049muscle filament slidingIDA12186860 |15923195 
GO:0051592response to calcium ionIMP8205619 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005861troponin complexIDA12186860 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
TNNI3CMD2A | CMH7 | MGC116817 | TNNC1 | cTnItroponin I type 3 (cardiac)Reconstituted ComplexBioGRID11904166 
TPM1C15orf13 | CMD1Y | HTM-alpha | TMSAtropomyosin 1 (alpha)Reconstituted ComplexBioGRID6746613 
 


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