Gene Page: UBE2V1
Summary ?
| GeneID | 7335 |
| Symbol | UBE2V1 |
| Synonyms | CIR1|CROC-1|CROC1|UBE2V|UEV-1|UEV1|UEV1A |
| Description | ubiquitin conjugating enzyme E2 V1 |
| Reference | MIM:602995|HGNC:HGNC:12494|Ensembl:ENSG00000244687|Vega:OTTHUMG00000152626 |
| Gene type | protein-coding |
| Map location | 20q13.2 |
| Sherlock p-value | 0.038 |
| Fetal beta | -0.026 |
| Support | G2Cdb.humanPSD G2Cdb.humanPSP |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C19orf36 | 0.75 | 0.75 |
| DCXR | 0.74 | 0.76 |
| MTHFS | 0.72 | 0.71 |
| KLHDC9 | 0.72 | 0.76 |
| PCBD1 | 0.72 | 0.69 |
| S100A6 | 0.68 | 0.74 |
| DYRK4 | 0.68 | 0.73 |
| RND2 | 0.66 | 0.70 |
| ABHD11 | 0.66 | 0.67 |
| UBTD1 | 0.66 | 0.71 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| C1orf96 | -0.57 | -0.63 |
| ZNF238 | -0.55 | -0.64 |
| PUM2 | -0.54 | -0.62 |
| ZEB2 | -0.54 | -0.63 |
| SPIRE1 | -0.53 | -0.61 |
| CDC2L6 | -0.53 | -0.62 |
| C14orf37 | -0.53 | -0.61 |
| HERC3 | -0.53 | -0.60 |
| GPR21 | -0.53 | -0.62 |
| NBEA | -0.53 | -0.61 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| PID IL1 PATHWAY | 34 | 28 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 20Q12 Q13 AMPLICON | 149 | 76 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| BONCI TARGETS OF MIR15A AND MIR16 1 | 91 | 75 | All SZGR 2.0 genes in this pathway |
| DANG REGULATED BY MYC DN | 253 | 192 | All SZGR 2.0 genes in this pathway |
| MARIADASON RESPONSE TO BUTYRATE CURCUMIN SULINDAC TSA 2 | 8 | 6 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| LINSLEY MIR16 TARGETS | 206 | 127 | All SZGR 2.0 genes in this pathway |
| TERAO AOX4 TARGETS HG UP | 28 | 20 | All SZGR 2.0 genes in this pathway |
| PEDRIOLI MIR31 TARGETS UP | 221 | 120 | All SZGR 2.0 genes in this pathway |