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| GeneID |
7391
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| Symbol |
USF1
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| Synonyms |
FCHL|FCHL1|HYPLIP1|MLTF|MLTFI|UEF|bHLHb11
|
| Description |
upstream transcription factor 1 |
| See related |
HGNC:12593|MIM:191523|Ensembl:ENSG00000158773|HPRD:01880| |
| Locus tag |
RP11-544M22.5 |
| Gene type |
protein-coding |
| Map location |
1q22-q23 |
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| Gene set name |
Method of gene set |
Evidence |
Info |
| GSMA_IIA | genome scan meta-analysis (All samples) | Psr: 0.00814 | |
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| General Gene Expression (microarray) ? |
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| Gene Expression in Brain Regions (new) |
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| Top co-expressed genes in Brain Regions (new) |
|
| Gene | Pearson's Correlation | Spearman's Correlation | | |
| Top 10 positively co-expressed genes |
| JDP2 | 0.80 | 0.82 | | |
| CHRD | 0.77 | 0.72 | | |
| LRRC38 | 0.77 | 0.72 | | |
| TMEM38A | 0.76 | 0.82 | | |
| NECAB3 | 0.76 | 0.62 | | |
| ITGA11 | 0.75 | 0.39 | | |
| FMNL1 | 0.75 | 0.70 | | |
| KCNIP3 | 0.75 | 0.83 | | |
| CX3CL1 | 0.75 | 0.81 | | |
| MICAL2 | 0.75 | 0.67 | | |
Top 10 negatively co-expressed genes | | TUBB2B | -0.44 | -0.60 | | |
| TRAF4 | -0.44 | -0.62 | | |
| KIAA1949 | -0.44 | -0.51 | | |
| COTL1 | -0.43 | -0.49 | | |
| AF186192.1 | -0.43 | -0.60 | | |
| IDH1 | -0.42 | -0.51 | | |
| CARHSP1 | -0.41 | -0.63 | | |
| LEMD1 | -0.41 | -0.55 | | |
| TMC2 | -0.41 | -0.60 | | |
| CD24 | -0.41 | -0.42 | | |
|
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0003705 | RNA polymerase II transcription factor activity, enhancer binding | IDA | | 2249772 |
| GO:0003705 | RNA polymerase II transcription factor activity, enhancer binding | IMP | | 8576131 |18234320 |
| GO:0005515 | protein binding | IPI | | 17353931 |
| GO:0043425 | bHLH transcription factor binding | IPI | | 8576131 |
| GO:0030528 | transcription regulator activity | IEA | | - |
| GO:0042803 | protein homodimerization activity | IPI | | 8576131 |
| GO:0042803 | protein homodimerization activity | TAS | | 2249772 |
| GO:0046982 | protein heterodimerization activity | IPI | | 8576131 |
| GO:0043565 | sequence-specific DNA binding | IDA | | 2249772 |8576131 |
| Biological process | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0000432 | positive regulation of transcription from RNA polymerase II promoter by glucose | IMP | | 7852331 |
| GO:0000432 | positive regulation of transcription from RNA polymerase II promoter by glucose | ISS | | - |
| GO:0001666 | response to hypoxia | IMP | | 12917334 |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | | - |
| GO:0006366 | transcription from RNA polymerase II promoter | IDA | | 2249772 |
| GO:0010552 | positive regulation of specific transcription from RNA polymerase II promoter | IMP | | 8576131 |18234320 |
| GO:0009411 | response to UV | ISS | | - |
| GO:0042593 | glucose homeostasis | TAS | | 15054483 |
| GO:0019086 | late viral mRNA transcription | IDA | | 2249772 |
| GO:0045449 | regulation of transcription | IEA | | - |
| GO:0055088 | lipid homeostasis | ISS | | - |
| GO:0051918 | negative regulation of fibrinolysis | IC | | 18234320 |
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|
| GO:0005634 | nucleus | IEA | | - |
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