SZGR2

Summary ?

GeneID	7431
Symbol	VIM
Synonyms	CTRCT30\|HEL113
Description	vimentin
Reference	MIM:193060\|HGNC:HGNC:12692\|Ensembl:ENSG00000026025\|HPRD:01899\|Vega:OTTHUMG00000017744
Gene type	protein-coding
Map location	10p13
Pascal p-value	0.213
Sherlock p-value	0.264
Fetal beta	2.193
eGene	Anterior cingulate cortex BA24 Cortex Myers' cis & trans
Support	G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS CompositeSet

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenics,schizophrenias	Click to show details

Section I. Genetics and epigenetics annotation

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	pvalue	qvalue	TSS distance	eQTL type
rs9451867	chr6	92659609	VIM	7431		0		trans
rs2199402	chr8	9201002	VIM	7431		0.05		trans
rs7841407	chr8	9243427	VIM	7431		0.01		trans
rs7007515	chr8	117444193	VIM	7431		0.15		trans
snp_a-2151892		0	VIM	7431		0.15		trans
rs17073665	chr13	81541961	VIM	7431		0.04		trans
rs11873703	chr18	61448702	VIM	7431		0.11		trans
rs7084057	10	17048022	VIM	ENSG00000026025.9	2.49916E-6	0.05	-222236	gtex_brain_ba24

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
FGFR1	0.68	0.58
MTTP	0.65	0.55
VANGL1	0.64	0.59
TMEM47	0.63	0.67
PLEKHG1	0.62	0.54
TNFRSF19	0.62	0.54
CTNNB1	0.61	0.66
LATS2	0.60	0.49
GNS	0.60	0.75
MDFIC	0.60	0.56

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AF347015.31	-0.32	-0.41
MT-CO2	-0.32	-0.41
AF347015.21	-0.31	-0.42
HIGD1B	-0.30	-0.40
AC098691.2	-0.30	-0.48
FXYD1	-0.30	-0.34
CXCL14	-0.30	-0.34
AF347015.33	-0.29	-0.34
AF347015.2	-0.29	-0.35
S100A13	-0.29	-0.36

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005515	protein binding	IDA		11889032
GO:0005515	protein binding	IPI		11827972
GO:0005200	structural constituent of cytoskeleton	IDA		11889032
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0006928	cell motion	TAS		16130169
GO:0044419	interspecies interaction between organisms	IEA		-
GO:0045103	intermediate filament-based process	IEA		-
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005856	cytoskeleton	TAS		16130169
GO:0005882	intermediate filament	IDA		11889032
GO:0005737	cytoplasm	IDA		9150946

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ABLIM1	ABLIM \| DKFZp781D0148 \| FLJ14564 \| KIAA0059 \| LIMAB1 \| LIMATIN \| MGC1224	actin binding LIM protein 1	Two-hybrid	BioGRID	16189514
ALS2CR11	FLJ25351 \| FLJ40332	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11	Two-hybrid	BioGRID	16189514
APIP	APIP2 \| CGI-29 \| MMRP19 \| dJ179L10.2	APAF1 interacting protein	Two-hybrid	BioGRID	16189514
ARS2	ASR2 \| MGC126427	arsenate resistance protein 2	Two-hybrid	BioGRID	16169070
ATN1	B37 \| D12S755E \| DRPLA \| NOD	atrophin 1	Two-hybrid	BioGRID	16169070
BFSP1	CP115 \| CP94 \| FILENSIN \| LIFL-H	beaded filament structural protein 1, filensin	-	HPRD,BioGRID	1478967 \|1918147
BHLHB2	DEC1 \| SHARP-2 \| STRA13 \| Stra14 \| bHLHe40	basic helix-loop-helix domain containing, class B, 2	Two-hybrid	BioGRID	16169070
BRD1	BRL \| BRPF1 \| BRPF2 \| DKFZp686F0325	bromodomain containing 1	Two-hybrid	BioGRID	16169070
C1orf103	FLJ11269 \| RIF1 \| RP11-96K19.1	chromosome 1 open reading frame 103	Two-hybrid	BioGRID	16169070
C7orf36	GK003	chromosome 7 open reading frame 36	Two-hybrid	BioGRID	16169070
CAPN1	CANP \| CANP1 \| CANPL1 \| muCANP \| muCL	calpain 1, (mu/I) large subunit	CAPN1 interacts with VIM.	BIND	12358155
CASP8	ALPS2B \| CAP4 \| FLICE \| FLJ17672 \| MACH \| MCH5 \| MGC78473	caspase 8, apoptosis-related cysteine peptidase	Two-hybrid	BioGRID	16169070
CDH5	7B4 \| CD144 \| FLJ17376	cadherin 5, type 2 (vascular endothelium)	-	HPRD,BioGRID	12003790
CRCT1	C1orf42 \| NICE-1	cysteine-rich C-terminal 1	Two-hybrid	BioGRID	16169070
CREB1	CREB \| MGC9284	cAMP responsive element binding protein 1	Two-hybrid	BioGRID	16169070
DCTN1	DAP-150 \| DP-150 \| HMN7B \| P135	dynactin 1 (p150, glued homolog, Drosophila)	-	HPRD,BioGRID	14600259
DIS3L2	FAM6A \| FLJ36974 \| MGC42174	DIS3 mitotic control homolog (S. cerevisiae)-like 2	Two-hybrid	BioGRID	16169070
DPPA4	2410091M23Rik \| FLJ10713	developmental pluripotency associated 4	Two-hybrid	BioGRID	16169070
DSP	DPI \| DPII	desmoplakin	-	HPRD,BioGRID	9261168
DYNLL1	DLC1 \| DLC8 \| DNCL1 \| DNCLC1 \| LC8 \| LC8a \| MGC126137 \| MGC126138 \| PIN \| hdlc1	dynein, light chain, LC8-type 1	-	HPRD	14760703
FABP4	A-FABP \| aP2	fatty acid binding protein 4, adipocyte	Two-hybrid	BioGRID	16169070
FAM107A	DRR1 \| FLJ30158 \| FLJ45473 \| TU3A	family with sequence similarity 107, member A	Two-hybrid	BioGRID	16189514
FUBP1	FBP \| FUBP	far upstream element (FUSE) binding protein 1	Two-hybrid	BioGRID	16169070
GFAP	FLJ45472	glial fibrillary acidic protein	Two-hybrid	BioGRID	16189514
GOPC	CAL \| FIG \| GOPC1 \| PIST \| dJ94G16.2	golgi associated PDZ and coiled-coil motif containing	Two-hybrid	BioGRID	16189514
HABP4	IHABP4 \| Ki-1/57 \| MGC825 \| SERBP1L	hyaluronan binding protein 4	Two-hybrid	BioGRID	16169070
HMG20B	BRAF25 \| BRAF35 \| FLJ26127 \| HMGX2 \| PP7706 \| SMARCE1r \| SOXL \| pp8857	high-mobility group 20B	Two-hybrid	BioGRID	16169070
IVNS1ABP	DKFZp686K06216 \| FLARA3 \| FLJ10069 \| FLJ10411 \| FLJ10962 \| FLJ35593 \| FLJ36593 \| HSPC068 \| KIAA0850 \| ND1 \| NS-1 \| NS1-BP \| NS1BP	influenza virus NS1A binding protein	Two-hybrid	BioGRID	16169070
KIAA0408	FLJ43995 \| RP3-403A15.2	KIAA0408	Two-hybrid	BioGRID	16189514
KIF15	FLJ25667 \| HKLP2 \| KNSL7 \| NY-BR-62	kinesin family member 15	Two-hybrid	BioGRID	16169070
KRT20	CD20 \| CK20 \| K20 \| KRT21 \| MGC35423	keratin 20	Two-hybrid	BioGRID	16189514
LOR	MGC111513	loricrin	Two-hybrid	BioGRID	16169070
MAFG	MGC13090 \| MGC20149	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	Two-hybrid	BioGRID	16169070
MAN2A2	MANA2X	mannosidase, alpha, class 2A, member 2	Two-hybrid	BioGRID	16169070
MEN1	MEAI \| SCG2	multiple endocrine neoplasia I	menin interacts with vimentin	BIND	12169273
MEN1	MEAI \| SCG2	multiple endocrine neoplasia I	-	HPRD,BioGRID	12169273
MICAL1	DKFZp434B1517 \| FLJ11937 \| FLJ21739 \| MICAL \| MICAL-1 \| NICAL	microtubule associated monoxygenase, calponin and LIM domain containing 1	-	HPRD,BioGRID	11827972
MRPL44	FLJ12701 \| FLJ13990 \| FLJ37688 \| L44MT \| MRP-L44	mitochondrial ribosomal protein L44	Two-hybrid	BioGRID	16169070
MYST2	HBO1 \| HBOA \| KAT7	MYST histone acetyltransferase 2	Two-hybrid	BioGRID	16169070 \|16189514
NFATC2	KIAA0611 \| NFAT1 \| NFATP	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	Two-hybrid	BioGRID	16169070
NIF3L1	ALS2CR1 \| CALS-7 \| MDS015	NIF3 NGG1 interacting factor 3-like 1 (S. pombe)	Two-hybrid	BioGRID	16189514
NME2	MGC111212 \| NDPK-B \| NDPKB \| NM23-H2 \| NM23B \| puf	non-metastatic cells 2, protein (NM23B) expressed in	-	HPRD,BioGRID	11082283
NOC4L	MGC3162 \| NOC4	nucleolar complex associated 4 homolog (S. cerevisiae)	Two-hybrid	BioGRID	16189514
NUP85	FLJ12549 \| Nup75	nucleoporin 85kDa	-	HPRD	12706117
OSBP2	ORP-4 \| ORP4 \| OSBPL1 \| OSBPL4	oxysterol binding protein 2	-	HPRD,BioGRID	11802775
PDLIM1	CLIM1 \| CLP-36 \| CLP36 \| hCLIM1	PDZ and LIM domain 1	Two-hybrid	BioGRID	16189514
PKN1	DBK \| MGC46204 \| PAK1 \| PKN \| PKN-ALPHA \| PRK1 \| PRKCL1	protein kinase N1	-	HPRD,BioGRID	9175763
PKP1	B6P \| MGC138829	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	-	HPRD,BioGRID	10852826
PLEC1	EBS1 \| EBSO \| HD1 \| PCN \| PLEC1b \| PLTN	plectin 1, intermediate filament binding protein 500kDa	-	HPRD,BioGRID	3027087
PPHLN1	HSPC206 \| HSPC232 \| MGC48786	periphilin 1	-	HPRD	15383276
PPL	KIAA0568 \| MGC134872	periplakin	-	HPRD,BioGRID	12366696
PSMA1	HC2 \| MGC14542 \| MGC14575 \| MGC14751 \| MGC1667 \| MGC21459 \| MGC22853 \| MGC23915 \| NU \| PROS30	proteasome (prosome, macropain) subunit, alpha type, 1	Two-hybrid	BioGRID	16189514
PSME1	IFI5111 \| MGC8628 \| PA28A \| PA28alpha \| REGalpha	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	Two-hybrid	BioGRID	16169070
PUF60	FIR \| FLJ31379 \| RoBPI \| SIAHBP1	poly-U binding splicing factor 60KDa	Two-hybrid	BioGRID	16169070
RAB8B	FLJ38125	RAB8B, member RAS oncogene family	-	HPRD,BioGRID	12639940
RABAC1	PRA1 \| PRAF1 \| YIP3	Rab acceptor 1 (prenylated)	Two-hybrid	BioGRID	16169070
RAD51	BRCC5 \| HRAD51 \| HsRad51 \| HsT16930 \| RAD51A \| RECA	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	Two-hybrid	BioGRID	16169070
RIBC2	C22orf11	RIB43A domain with coiled-coils 2	Two-hybrid	BioGRID	16189514
SDCCAG3	NY-CO-3	serologically defined colon cancer antigen 3	Two-hybrid	BioGRID	16169070
SERBP1	CGI-55 \| CHD3IP \| DKFZp564M2423 \| FLJ90489 \| HABP4L \| PAI-RBP1 \| PAIRBP1	SERPINE1 mRNA binding protein 1	Two-hybrid	BioGRID	16169070
SH3YL1	DKFZp586F1318 \| FLJ39121 \| Ray	SH3 domain containing, Ysc84-like 1 (S. cerevisiae)	Two-hybrid	BioGRID	16169070
SIRT6	SIR2L6	sirtuin (silent mating type information regulation 2 homolog) 6 (S. cerevisiae)	Two-hybrid	BioGRID	16169070
SLC25A6	AAC3 \| ANT3 \| ANT3Y \| MGC17525	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	Two-hybrid	BioGRID	16169070
SLC27A6	ACSVL2 \| DKFZp779M0564 \| FACVL2 \| FATP6 \| VLCS-H1	solute carrier family 27 (fatty acid transporter), member 6	Two-hybrid	BioGRID	16169070
STX1A	HPC-1 \| STX1 \| p35-1	syntaxin 1A (brain)	Two-hybrid	BioGRID	16169070
SUMO2	HSMT3 \| MGC117191 \| SMT3B \| SMT3H2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	Two-hybrid	BioGRID	16169070
SUMO3	SMT3A \| SMT3H1 \| SUMO-3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	Two-hybrid	BioGRID	16169070
SYN1	SYN1a \| SYN1b \| SYNI	synapsin I	Two-hybrid	BioGRID	16169070
TCHP	MGC10854	trichoplein, keratin filament binding	Two-hybrid	BioGRID	16189514
TNFRSF14	ATAR \| HVEA \| HVEM \| LIGHTR \| TR2	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	Two-hybrid	BioGRID	16169070
TRADD	Hs.89862 \| MGC11078	TNFRSF1A-associated via death domain	-	HPRD	14743216
TRIM28	FLJ29029 \| KAP1 \| RNF96 \| TF1B \| TIF1B	tripartite motif-containing 28	Two-hybrid	BioGRID	16169070
TRIM29	ATDC \| FLJ36085	tripartite motif-containing 29	-	HPRD	7644499
TRIOBP	DFNB28 \| FLJ39315 \| HRIHFB2122 \| KIAA1662 \| TARA \| dJ37E16.4	TRIO and F-actin binding protein	Two-hybrid	BioGRID	16169070
TTR	HsT2651 \| PALB \| TBPA	transthyretin	Two-hybrid	BioGRID	16169070
TUBGCP4	76P \| FLJ14797 \| GCP4	tubulin, gamma complex associated protein 4	Two-hybrid	BioGRID	16189514
TXN	DKFZp686B1993 \| MGC61975 \| TRX \| TRX1	thioredoxin	Two-hybrid	BioGRID	12099690
UPP1	UDRPASE \| UP \| UPASE \| UPP	uridine phosphorylase 1	-	HPRD,BioGRID	11278417
UPP2	UDRPASE2 \| UP2 \| UPASE2	uridine phosphorylase 2	-	HPRD,BioGRID	11278417
VIM	FLJ36605	vimentin	-	HPRD,BioGRID	11243787 \|11889032
WBP11	DKFZp779M1063 \| NPWBP \| SIPP1	WW domain binding protein 11	-	HPRD	11375989
XRCC4	-	X-ray repair complementing defective repair in Chinese hamster cells 4	Two-hybrid	BioGRID	16169070
YWHAZ	KCIP-1 \| MGC111427 \| MGC126532 \| MGC138156	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	-	HPRD,BioGRID	10887173

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
PID AURORA B PATHWAY	39	24	All SZGR 2.0 genes in this pathway
PID CASPASE PATHWAY	52	39	All SZGR 2.0 genes in this pathway
REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	40	26	All SZGR 2.0 genes in this pathway
REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	13	11	All SZGR 2.0 genes in this pathway
REACTOME STRIATED MUSCLE CONTRACTION	27	12	All SZGR 2.0 genes in this pathway
REACTOME MUSCLE CONTRACTION	48	24	All SZGR 2.0 genes in this pathway
REACTOME APOPTOSIS	148	94	All SZGR 2.0 genes in this pathway
REACTOME APOPTOTIC EXECUTION PHASE	54	37	All SZGR 2.0 genes in this pathway
HOLLMANN APOPTOSIS VIA CD40 DN	267	178	All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE UP	485	293	All SZGR 2.0 genes in this pathway
HOOI ST7 TARGETS DN	123	78	All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL DN	460	312	All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION DN	329	219	All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN	805	505	All SZGR 2.0 genes in this pathway
OLSSON E2F3 TARGETS DN	49	33	All SZGR 2.0 genes in this pathway
OHASHI AURKB TARGETS	10	6	All SZGR 2.0 genes in this pathway
HONRADO BREAST CANCER BRCA1 VS BRCA2	18	12	All SZGR 2.0 genes in this pathway
PATIL LIVER CANCER	747	453	All SZGR 2.0 genes in this pathway
TSUNODA CISPLATIN RESISTANCE UP	15	7	All SZGR 2.0 genes in this pathway
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL UP	83	51	All SZGR 2.0 genes in this pathway
CALVET IRINOTECAN SENSITIVE VS REVERTED UP	5	5	All SZGR 2.0 genes in this pathway
KHETCHOUMIAN TRIM24 TARGETS UP	47	38	All SZGR 2.0 genes in this pathway
FRIDMAN SENESCENCE UP	77	60	All SZGR 2.0 genes in this pathway
WU CELL MIGRATION	184	114	All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS	988	594	All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS	734	436	All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION UP	71	51	All SZGR 2.0 genes in this pathway
DORSAM HOXA9 TARGETS UP	35	25	All SZGR 2.0 genes in this pathway
IIZUKA LIVER CANCER EARLY RECURRENCE	11	10	All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP	555	346	All SZGR 2.0 genes in this pathway
FERRANDO T ALL WITH MLL ENL FUSION UP	87	67	All SZGR 2.0 genes in this pathway
LEI MYB TARGETS	318	215	All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND DN	225	163	All SZGR 2.0 genes in this pathway
JIANG AGING CEREBRAL CORTEX UP	36	27	All SZGR 2.0 genes in this pathway
WESTON VEGFA TARGETS 6HR	59	38	All SZGR 2.0 genes in this pathway
HARRIS HYPOXIA	81	64	All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE UP	249	170	All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN	830	547	All SZGR 2.0 genes in this pathway
WESTON VEGFA TARGETS 12HR	35	23	All SZGR 2.0 genes in this pathway
WESTON VEGFA TARGETS	108	71	All SZGR 2.0 genes in this pathway
APRELIKOVA BRCA1 TARGETS	49	33	All SZGR 2.0 genes in this pathway
LU AGING BRAIN UP	262	186	All SZGR 2.0 genes in this pathway
LEE AGING NEOCORTEX UP	89	59	All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP	487	303	All SZGR 2.0 genes in this pathway
BAELDE DIABETIC NEPHROPATHY DN	434	302	All SZGR 2.0 genes in this pathway
ZHONG SECRETOME OF LUNG CANCER AND ENDOTHELIUM	66	47	All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER T7	98	63	All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE DN	195	135	All SZGR 2.0 genes in this pathway
KYNG ENVIRONMENTAL STRESS RESPONSE UP	56	41	All SZGR 2.0 genes in this pathway
TING SILENCED BY DICER	31	17	All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER UP	973	570	All SZGR 2.0 genes in this pathway
LABBE TGFB1 TARGETS UP	102	64	All SZGR 2.0 genes in this pathway
BRUECKNER TARGETS OF MIRLET7A3 DN	78	49	All SZGR 2.0 genes in this pathway
MATTHEWS AP1 TARGETS	17	12	All SZGR 2.0 genes in this pathway
BLUM RESPONSE TO SALIRASIB UP	245	159	All SZGR 2.0 genes in this pathway
WINTER HYPOXIA METAGENE	242	168	All SZGR 2.0 genes in this pathway
WANG TUMOR INVASIVENESS UP	374	247	All SZGR 2.0 genes in this pathway
GU PDEF TARGETS UP	71	49	All SZGR 2.0 genes in this pathway
CHAUHAN RESPONSE TO METHOXYESTRADIOL DN	102	65	All SZGR 2.0 genes in this pathway
NUTT GBM VS AO GLIOMA UP	46	34	All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP	1305	895	All SZGR 2.0 genes in this pathway
HINATA NFKB TARGETS KERATINOCYTE UP	91	63	All SZGR 2.0 genes in this pathway
HINATA NFKB TARGETS FIBROBLAST UP	84	60	All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK	1210	725	All SZGR 2.0 genes in this pathway
HSIAO HOUSEKEEPING GENES	389	245	All SZGR 2.0 genes in this pathway
MEISSNER BRAIN HCP WITH H3K4ME3 AND H3K27ME3	1069	729	All SZGR 2.0 genes in this pathway
ROME INSULIN TARGETS IN MUSCLE UP	442	263	All SZGR 2.0 genes in this pathway
COULOUARN TEMPORAL TGFB1 SIGNATURE UP	109	68	All SZGR 2.0 genes in this pathway
LEE LIVER CANCER HEPATOBLAST	16	12	All SZGR 2.0 genes in this pathway
YAGI AML WITH INV 16 TRANSLOCATION	422	277	All SZGR 2.0 genes in this pathway
MARSON FOXP3 TARGETS UP	66	43	All SZGR 2.0 genes in this pathway
NGO MALIGNANT GLIOMA 1P LOH	17	13	All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP	307	182	All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE DN	841	431	All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP	756	494	All SZGR 2.0 genes in this pathway
KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP	682	440	All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS CONFLUENT	567	365	All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN	1972	1213	All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 UP	430	288	All SZGR 2.0 genes in this pathway
KIM GLIS2 TARGETS UP	84	61	All SZGR 2.0 genes in this pathway
MIKHAYLOVA OXIDATIVE STRESS RESPONSE VIA VHL UP	7	6	All SZGR 2.0 genes in this pathway
PASINI SUZ12 TARGETS DN	315	215	All SZGR 2.0 genes in this pathway
VANDESLUIS NORMAL EMBRYOS DN	25	13	All SZGR 2.0 genes in this pathway
BILANGES RAPAMYCIN SENSITIVE VIA TSC1 AND TSC2	73	37	All SZGR 2.0 genes in this pathway
TORCHIA TARGETS OF EWSR1 FLI1 FUSION DN	321	200	All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3	824	528	All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP	570	339	All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS UP	163	111	All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 36HR	152	88	All SZGR 2.0 genes in this pathway
KRIEG HYPOXIA NOT VIA KDM3A	770	480	All SZGR 2.0 genes in this pathway
HOLLEMAN VINCRISTINE RESISTANCE B ALL DN	15	10	All SZGR 2.0 genes in this pathway
HOLLEMAN VINCRISTINE RESISTANCE ALL DN	19	11	All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL UP	489	314	All SZGR 2.0 genes in this pathway
LIM MAMMARY LUMINAL MATURE DN	99	74	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-124/506	81	87	m8	hsa-miR-506	UAAGGCACCCUUCUGAGUAGA
miR-124/506	81	87	m8	hsa-miR-124^brain	UAAGGCACGCGGUGAAUGCC
miR-138	32	38	1A	hsa-miR-138^brain	AGCUGGUGUUGUGAAUC
miR-30-5p	178	184	1A	hsa-miR-30a-5p	UGUAAACAUCCUCGACUGGAAG
				hsa-miR-30c^brain	UGUAAACAUCCUACACUCUCAGC
				hsa-miR-30d^SZ	UGUAAACAUCCCCGACUGGAAG
				hsa-miR-30b^SZ	UGUAAACAUCCUACACUCAGCU
				hsa-miR-30e-5p	UGUAAACAUCCUUGACUGGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.

Gene Page: VIM