Summary ?
GeneID7582
SymbolZNF33B
SynonymsKOX2|KOX31|ZNF11B
Descriptionzinc finger protein 33B
ReferenceMIM:194522|HGNC:HGNC:13097|Ensembl:ENSG00000196693|HPRD:01912|Vega:OTTHUMG00000018014
Gene typeprotein-coding
Map location10q11.2
Pascal p-value0.606
Sherlock p-value0.237
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs1368303chr5147672388ZNF33B75820.08trans
rs7314267chr1276291887ZNF33B75820.19trans
rs109002511043074704ZNF33BENSG00000196693.102.922E-60.0459288gtex_brain_ba24
rs79198801043082704ZNF33BENSG00000196693.104.244E-60.0451288gtex_brain_ba24
rs608186371043085636ZNF33BENSG00000196693.104.244E-60.0448356gtex_brain_ba24
rs79109691043085664ZNF33BENSG00000196693.104.244E-60.0448328gtex_brain_ba24
rs79046271043089156ZNF33BENSG00000196693.104.244E-60.0444836gtex_brain_ba24
rs70977661043105345ZNF33BENSG00000196693.104.244E-60.0428647gtex_brain_ba24
rs603965971043119413ZNF33BENSG00000196693.104.437E-60.0414579gtex_brain_ba24
rs122568671043125900ZNF33BENSG00000196693.104.251E-60.048092gtex_brain_ba24
rs1128628531043131140ZNF33BENSG00000196693.104.242E-60.042852gtex_brain_ba24
rs114990921042982645ZNF33BENSG00000196693.102.39E-60151347gtex_brain_putamen_basal
rs112396151042982655ZNF33BENSG00000196693.102.39E-60151337gtex_brain_putamen_basal
rs114990931042982790ZNF33BENSG00000196693.102.191E-60151202gtex_brain_putamen_basal
rs1119630141042984483ZNF33BENSG00000196693.101.19E-60149509gtex_brain_putamen_basal
rs18554511042985674ZNF33BENSG00000196693.102.292E-60148318gtex_brain_putamen_basal
rs112396161042986286ZNF33BENSG00000196693.102.312E-60147706gtex_brain_putamen_basal
rs112396171042986318ZNF33BENSG00000196693.102.207E-60147674gtex_brain_putamen_basal
rs122184031042987445ZNF33BENSG00000196693.102.344E-60146547gtex_brain_putamen_basal
rs70761701042987690ZNF33BENSG00000196693.102.349E-60146302gtex_brain_putamen_basal
rs70971531042988023ZNF33BENSG00000196693.102.36E-60145969gtex_brain_putamen_basal
rs70766241042988071ZNF33BENSG00000196693.102.36E-60145921gtex_brain_putamen_basal
rs70972991042988114ZNF33BENSG00000196693.102.365E-60145878gtex_brain_putamen_basal
rs70767871042988152ZNF33BENSG00000196693.102.365E-60145840gtex_brain_putamen_basal
rs775928811042989375ZNF33BENSG00000196693.102.386E-60144617gtex_brain_putamen_basal
rs732566801042990056ZNF33BENSG00000196693.102.386E-60143936gtex_brain_putamen_basal
rs732566821042990192ZNF33BENSG00000196693.102.386E-60143800gtex_brain_putamen_basal
rs1138371551042990385ZNF33BENSG00000196693.102.375E-60143607gtex_brain_putamen_basal
rs1132934161042991185ZNF33BENSG00000196693.102.386E-60142807gtex_brain_putamen_basal
rs732566991042991710ZNF33BENSG00000196693.102.386E-60142282gtex_brain_putamen_basal
rs1133466271042992019ZNF33BENSG00000196693.102.386E-60141973gtex_brain_putamen_basal
rs2102521043027251ZNF33BENSG00000196693.108.022E-70106741gtex_brain_putamen_basal
rs597604651043034419ZNF33BENSG00000196693.102.616E-6099573gtex_brain_putamen_basal
rs732626311043050866ZNF33BENSG00000196693.102.386E-6083126gtex_brain_putamen_basal
rs171573441043063910ZNF33BENSG00000196693.102.386E-6070082gtex_brain_putamen_basal
rs97333251043064627ZNF33BENSG00000196693.102.386E-6069365gtex_brain_putamen_basal
rs127765031043066936ZNF33BENSG00000196693.102.386E-6067056gtex_brain_putamen_basal
rs70978811043070527ZNF33BENSG00000196693.102.386E-6063465gtex_brain_putamen_basal
rs79216581043075288ZNF33BENSG00000196693.102.386E-6058704gtex_brain_putamen_basal
rs2102851043079348ZNF33BENSG00000196693.101.583E-6054644gtex_brain_putamen_basal
rs65934131043082961ZNF33BENSG00000196693.101.56E-6051031gtex_brain_putamen_basal
rs109002531043084726ZNF33BENSG00000196693.101.555E-6049266gtex_brain_putamen_basal
rs1112396361043085232ZNF33BENSG00000196693.104.162E-6048760gtex_brain_putamen_basal
rs24193681043087295ZNF33BENSG00000196693.101.555E-6046697gtex_brain_putamen_basal
rs2102821043087649ZNF33BENSG00000196693.103.67E-6046343gtex_brain_putamen_basal
rs2102811043087763ZNF33BENSG00000196693.103.665E-6046229gtex_brain_putamen_basal
rs2102801043089965ZNF33BENSG00000196693.101.9E-7044027gtex_brain_putamen_basal
rs2093751043095722ZNF33BENSG00000196693.101.078E-6038270gtex_brain_putamen_basal
rs1583691043097402ZNF33BENSG00000196693.101.576E-6036590gtex_brain_putamen_basal
rs2093761043100240ZNF33BENSG00000196693.101.26E-6033752gtex_brain_putamen_basal
rs3978105551043102788ZNF33BENSG00000196693.101.052E-6031204gtex_brain_putamen_basal
rs14133931043104068ZNF33BENSG00000196693.103.459E-6029924gtex_brain_putamen_basal
rs1583791043108931ZNF33BENSG00000196693.101.576E-6025061gtex_brain_putamen_basal
rs2093781043111245ZNF33BENSG00000196693.101.576E-6022747gtex_brain_putamen_basal
rs2093791043111670ZNF33BENSG00000196693.101.184E-6022322gtex_brain_putamen_basal
rs1116021121043112233ZNF33BENSG00000196693.103.459E-6021759gtex_brain_putamen_basal
rs3978164441043113285ZNF33BENSG00000196693.106.557E-7020707gtex_brain_putamen_basal
rs2093811043114560ZNF33BENSG00000196693.102.224E-7019432gtex_brain_putamen_basal
rs732666341043115683ZNF33BENSG00000196693.103.459E-6018309gtex_brain_putamen_basal
rs2093931043122411ZNF33BENSG00000196693.101.422E-6011581gtex_brain_putamen_basal
rs2093921043126641ZNF33BENSG00000196693.106.427E-707351gtex_brain_putamen_basal
rs2093901043128880ZNF33BENSG00000196693.101.052E-605112gtex_brain_putamen_basal
rs2093891043130471ZNF33BENSG00000196693.101.049E-603521gtex_brain_putamen_basal
rs1583861043131363ZNF33BENSG00000196693.101.556E-602629gtex_brain_putamen_basal
rs2093871043132232ZNF33BENSG00000196693.103.421E-601760gtex_brain_putamen_basal
rs2093861043133535ZNF33BENSG00000196693.101.043E-60457gtex_brain_putamen_basal
rs37403291043134086ZNF33BENSG00000196693.101.894E-70-94gtex_brain_putamen_basal
rs2102991043139232ZNF33BENSG00000196693.105.629E-70-5240gtex_brain_putamen_basal
rs2103001043139267ZNF33BENSG00000196693.101.433E-60-5275gtex_brain_putamen_basal
rs598185291043140713ZNF33BENSG00000196693.103.299E-60-6721gtex_brain_putamen_basal
rs6835381043148854ZNF33BENSG00000196693.103.45E-60-14862gtex_brain_putamen_basal
rs70722001043153418ZNF33BENSG00000196693.103.534E-60-19426gtex_brain_putamen_basal
rs70883891043191254ZNF33BENSG00000196693.103.566E-60-57262gtex_brain_putamen_basal
rs70990131043191739ZNF33BENSG00000196693.103.566E-60-57747gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
RBM15B0.980.98
ZBTB120.970.93
ZSWIM40.960.95
CSNK1E0.960.97
GTF2IRD10.960.94
LDB10.960.95
DBN10.960.97
NUP620.960.95
KDM4B0.950.97
ZNF710.950.97
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
C5orf53-0.72-0.79
HLA-F-0.71-0.78
AIFM3-0.71-0.78
AF347015.27-0.71-0.93
S100B-0.70-0.87
ALDOC-0.70-0.73
AF347015.31-0.70-0.91
HEPN1-0.69-0.76
CLU-0.69-0.72
MT-CO2-0.69-0.92

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME GENERIC TRANSCRIPTION PATHWAY 352181All SZGR 2.0 genes in this pathway
GAZDA DIAMOND BLACKFAN ANEMIA ERYTHROID DN 493298All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 DN 229142All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442892All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953554All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783442All SZGR 2.0 genes in this pathway
MOOTHA HUMAN MITODB 6 2002 429260All SZGR 2.0 genes in this pathway
MOOTHA PGC 420269All SZGR 2.0 genes in this pathway
MOOTHA MITOCHONDRIA 447277All SZGR 2.0 genes in this pathway
MOOTHA ROS 77All SZGR 2.0 genes in this pathway