Summary ?
GeneID78991
SymbolPCYOX1L
Synonyms-
Descriptionprenylcysteine oxidase 1 like
ReferenceHGNC:HGNC:28477|Ensembl:ENSG00000145882|HPRD:14552|Vega:OTTHUMG00000130052
Gene typeprotein-coding
Map location5q32
Pascal p-value0.026
Sherlock p-value0.872
eGeneCaudate basal ganglia

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IGenome scan meta-analysisPsr: 0.0032 
GSMA_IIEGenome scan meta-analysis (European-ancestry samples)Psr: 0.01718 
GSMA_IIAGenome scan meta-analysis (All samples)Psr: 0.00459 

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
C19orf260.820.87
DMWD0.800.83
MAP3K100.800.82
BEGAIN0.800.83
AL355987.10.800.84
RNF2080.790.83
DVL10.790.81
NEURL0.790.82
SEMA6B0.790.83
FBXO440.790.79
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
NOSTRIN-0.40-0.34
GNG11-0.38-0.37
CLEC2B-0.38-0.27
AP002478.3-0.38-0.33
AF347015.21-0.37-0.24
AF347015.31-0.36-0.25
MT-CO2-0.35-0.23
AF347015.18-0.35-0.19
C1orf54-0.35-0.29
RAB13-0.34-0.42

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0016670oxidoreductase activity, acting on sulfur group of donors, oxygen as acceptorIEA-
GO:0016491oxidoreductase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0055114oxidation reductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
HAHTOLA MYCOSIS FUNGOIDES CD4 DN 11671All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN 1024594All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS DN 637377All SZGR 2.0 genes in this pathway
BILD MYC ONCOGENIC SIGNATURE 206117All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL TUMOR UP 294199All SZGR 2.0 genes in this pathway
YAUCH HEDGEHOG SIGNALING PARACRINE UP 14985All SZGR 2.0 genes in this pathway
WIERENGA STAT5A TARGETS DN 213127All SZGR 2.0 genes in this pathway