Gene Page: CUEDC2
Summary ?
| GeneID | 79004 |
| Symbol | CUEDC2 |
| Synonyms | C10orf66|bA18I14.5 |
| Description | CUE domain containing 2 |
| Reference | MIM:614142|HGNC:HGNC:28352|Ensembl:ENSG00000107874|HPRD:13099|Vega:OTTHUMG00000018958 |
| Gene type | protein-coding |
| Map location | 10q24.32 |
| Pascal p-value | 1.825E-4 |
| Sherlock p-value | 0.212 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs7132043 | chr12 | 80968399 | CUEDC2 | 79004 | 0.15 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| COQ6 | 0.81 | 0.78 |
| GABARAP | 0.79 | 0.78 |
| ADSL | 0.79 | 0.78 |
| VRK3 | 0.78 | 0.75 |
| WDR61 | 0.78 | 0.77 |
| AUP1 | 0.78 | 0.72 |
| TUSC4 | 0.77 | 0.75 |
| MPDU1 | 0.77 | 0.71 |
| PSMA5 | 0.77 | 0.76 |
| THYN1 | 0.77 | 0.72 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.26 | -0.60 | -0.60 |
| AF347015.8 | -0.59 | -0.55 |
| MT-CYB | -0.58 | -0.55 |
| AF347015.18 | -0.58 | -0.62 |
| AF347015.2 | -0.58 | -0.55 |
| AF347015.15 | -0.58 | -0.55 |
| MT-ATP8 | -0.56 | -0.58 |
| AF347015.27 | -0.56 | -0.53 |
| MT-CO2 | -0.55 | -0.50 |
| AF347015.33 | -0.54 | -0.53 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | 517 | 309 | All SZGR 2.0 genes in this pathway |
| LE EGR2 TARGETS UP | 108 | 75 | All SZGR 2.0 genes in this pathway |
| PAL PRMT5 TARGETS UP | 203 | 135 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | 863 | 514 | All SZGR 2.0 genes in this pathway |
| ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
| CHUNG BLISTER CYTOTOXICITY UP | 134 | 84 | All SZGR 2.0 genes in this pathway |
| WEST ADRENOCORTICAL TUMOR DN | 546 | 362 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 13 | 172 | 107 | All SZGR 2.0 genes in this pathway |
| LI DCP2 BOUND MRNA | 89 | 57 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |