Summary ?
GeneID79675
SymbolFASTKD1
Synonyms-
DescriptionFAST kinase domains 1
ReferenceHGNC:HGNC:26150|Ensembl:ENSG00000138399|HPRD:07969|Vega:OTTHUMG00000154953
Gene typeprotein-coding
Map location2q31
Pascal p-value0.155
Sherlock p-value0.116
Fetal beta0.434
DMG1 (# studies)
eGeneCaudate basal ganglia
Cerebellum
Hypothalamus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg239284352170430788FASTKD13.672E-40.4420.042DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs1126515212170346004FASTKD1ENSG00000138399.137.701E-8084381gtex_brain_putamen_basal
rs73492742170386294FASTKD1ENSG00000138399.132.144E-8044091gtex_brain_putamen_basal
rs730379612170389032FASTKD1ENSG00000138399.132.144E-8041353gtex_brain_putamen_basal
rs168570202170390189FASTKD1ENSG00000138399.132.144E-8040196gtex_brain_putamen_basal
rs793714512170399190FASTKD1ENSG00000138399.131.596E-8031195gtex_brain_putamen_basal
rs124708092170401673FASTKD1ENSG00000138399.132.399E-8028712gtex_brain_putamen_basal
rs22900102170402752FASTKD1ENSG00000138399.133.265E-8027633gtex_brain_putamen_basal
rs126200492170404926FASTKD1ENSG00000138399.133.265E-8025459gtex_brain_putamen_basal
rs799365072170409031FASTKD1ENSG00000138399.133.265E-8021354gtex_brain_putamen_basal
rs762163362170409372FASTKD1ENSG00000138399.133.265E-8021013gtex_brain_putamen_basal
rs124758142170410165FASTKD1ENSG00000138399.133.281E-7020220gtex_brain_putamen_basal
rs124759582170410415FASTKD1ENSG00000138399.133.265E-8019970gtex_brain_putamen_basal
rs124785682170414166FASTKD1ENSG00000138399.133.265E-8016219gtex_brain_putamen_basal
rs120522382170415441FASTKD1ENSG00000138399.133.265E-8014944gtex_brain_putamen_basal
rs168570422170419108FASTKD1ENSG00000138399.133.265E-8011277gtex_brain_putamen_basal
rs124670472170427222FASTKD1ENSG00000138399.137.802E-703163gtex_brain_putamen_basal
rs7462712170429975FASTKD1ENSG00000138399.137.904E-70410gtex_brain_putamen_basal
rs23531922170430388FASTKD1ENSG00000138399.137.904E-70-3gtex_brain_putamen_basal
rs793301622170432599FASTKD1ENSG00000138399.134.303E-70-2214gtex_brain_putamen_basal
rs776925772170433867FASTKD1ENSG00000138399.134.4E-70-3482gtex_brain_putamen_basal
rs23531932170434063FASTKD1ENSG00000138399.134.4E-70-3678gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
ONKEN UVEAL MELANOMA UP 783507All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA UP 294178All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579346All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION MONOCYTE UP 204140All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP 557331All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA DN 284156All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS DN 459276All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375806All SZGR 2.0 genes in this pathway
KIM MYC AMPLIFICATION TARGETS UP 201127All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS EARLY PROGENITOR 532309All SZGR 2.0 genes in this pathway
MONNIER POSTRADIATION TUMOR ESCAPE UP 393244All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS UP 388234All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO CSF2RB AND IL4 UP 338225All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO HGF UP 418282All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO HGF VS CSF2RB AND IL4 UP 408276All SZGR 2.0 genes in this pathway
STEIN ESRRA TARGETS 535325All SZGR 2.0 genes in this pathway
FOURNIER ACINAR DEVELOPMENT LATE 2 277172All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP 605377All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718401All SZGR 2.0 genes in this pathway
MIKKELSEN NPC ICP WITH H3K4ME3 445257All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882538All SZGR 2.0 genes in this pathway