Gene Page: ZBBX
Summary ?
| GeneID | 79740 |
| Symbol | ZBBX |
| Synonyms | - |
| Description | zinc finger B-box domain containing |
| Reference | HGNC:HGNC:26245|Ensembl:ENSG00000169064|HPRD:08015|Vega:OTTHUMG00000133560 |
| Gene type | protein-coding |
| Map location | 3q26.1 |
| Pascal p-value | 0.049 |
| DEG p-value | DEG:Maycox_2009:CC_BA10_fold_change=-1.19:CC_BA10_disease_P=0.0475:HBB_BA9_fold_change=-1.29:HBB_BA9_disease_P=0.0401 |
| Fetal beta | -1.939 |
| eGene | Frontal Cortex BA9 Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DEG:Maycox_2009 | Microarray to determine the expression of over 30000 mRNA transcripts in post-mortem tissue | We included 51 genes whose expression changes are common between two schizophrenia cohorts. |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| snp_a-1953711 | 0 | ZBBX | 79740 | 0.09 | trans | |||
| rs17027341 | chr2 | 103136558 | ZBBX | 79740 | 0.18 | trans | ||
| rs7604419 | chr2 | 123489906 | ZBBX | 79740 | 0.2 | trans | ||
| rs8128279 | chr21 | 43369058 | ZBBX | 79740 | 0.15 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| SENGUPTA NASOPHARYNGEAL CARCINOMA DN | 349 | 157 | All SZGR 2.0 genes in this pathway |
| LEE NEURAL CREST STEM CELL DN | 118 | 79 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| SILIGAN BOUND BY EWS FLT1 FUSION | 47 | 34 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS MATURE CELL | 293 | 160 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 | 473 | 224 | All SZGR 2.0 genes in this pathway |
| HELLER HDAC TARGETS UP | 317 | 208 | All SZGR 2.0 genes in this pathway |