Summary ?
Descriptionnon-homologous end joining factor 1
Gene typeprotein-coding
Map location2q35
Pascal p-value7.874E-4

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IIEGenome scan meta-analysis (European-ancestry samples)Psr: 0.01016 
GSMA_IIAGenome scan meta-analysis (All samples)Psr: 0.00916 
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 

Section I. Genetics and epigenetics annotation

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003677DNA bindingIEA-
GO:0042802identical protein bindingIPI16439205 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007417central nervous system developmentNASBrain (GO term level: 6)16439204 
GO:0006303double-strand break repair via nonhomologous end joiningIMP16439204 |16439205 
GO:0006281DNA repairIEA-
GO:0010212response to ionizing radiationIDA16439205 
GO:0051351positive regulation of ligase activityNAS16439205 
GO:0030217T cell differentiationIMP16439204 
GO:0030183B cell differentiationIMP16439204 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA16439204 |16439205 

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG NON HOMOLOGOUS END JOINING 148All SZGR 2.0 genes in this pathway
PID DNA PK PATHWAY 1610All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR 544307All SZGR 2.0 genes in this pathway
XU GH1 EXOGENOUS TARGETS UP 8550All SZGR 2.0 genes in this pathway
XU GH1 AUTOCRINE TARGETS UP 268157All SZGR 2.0 genes in this pathway
WOO LIVER CANCER RECURRENCE DN 8054All SZGR 2.0 genes in this pathway
KASLER HDAC7 TARGETS 1 UP 194133All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG BOUND 8D 658397All SZGR 2.0 genes in this pathway
KRIEG KDM3A TARGETS NOT HYPOXIA 208107All SZGR 2.0 genes in this pathway