Summary ?
GeneID80018
SymbolNAA25
SynonymsC12orf30|MDM20|NAP1
DescriptionN(alpha)-acetyltransferase 25, NatB auxiliary subunit
ReferenceMIM:612755|HGNC:HGNC:25783|Ensembl:ENSG00000111300|HPRD:08578|Vega:OTTHUMG00000169638
Gene typeprotein-coding
Map location12q24.13
Pascal p-value0.216
Fetal beta0.466
DMG1 (# studies)
eGeneCaudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Putamen basal ganglia

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
CV:PheWASPhenome-wide association studies (PheWAS)157 SNPs associated with schizophrenia 1
DMG:Wockner_2014Genome-wide DNA methylation analysisThis dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@CV:PheWAS

SNP IDChromosomePositionAllelePFunctionGeneUp/Down Distance
rs1769673612112486818null0.6809NAA25null

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg1870074412112534559NAA253.967E-4-0.4880.044DMG:Wockner_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs5837638412112287753NAA25ENSG00000111300.52.389E-60.01259073gtex_brain_putamen_basal
rs7721149112112322778NAA25ENSG00000111300.52.402E-60.01224048gtex_brain_putamen_basal
rs1694172412112327057NAA25ENSG00000111300.52.389E-60.01219769gtex_brain_putamen_basal
rs7703080812112329028NAA25ENSG00000111300.52.389E-60.01217798gtex_brain_putamen_basal
rs1258024612112331317NAA25ENSG00000111300.52.389E-60.01215509gtex_brain_putamen_basal
rs7579765612112340341NAA25ENSG00000111300.52.408E-60.01206485gtex_brain_putamen_basal
rs7872914212112357260NAA25ENSG00000111300.52.389E-60.01189566gtex_brain_putamen_basal
rs1258017512112364512NAA25ENSG00000111300.52.389E-60.01182314gtex_brain_putamen_basal
rs6101285612112365491NAA25ENSG00000111300.52.389E-60.01181335gtex_brain_putamen_basal
rs7997609012112366118NAA25ENSG00000111300.52.389E-60.01180708gtex_brain_putamen_basal
rs5874223812112366324NAA25ENSG00000111300.52.389E-60.01180502gtex_brain_putamen_basal
rs5913116812112368363NAA25ENSG00000111300.52.389E-60.01178463gtex_brain_putamen_basal
rs5983637212112369878NAA25ENSG00000111300.52.389E-60.01176948gtex_brain_putamen_basal
rs1258210012112378909NAA25ENSG00000111300.52.447E-60.01167917gtex_brain_putamen_basal
rs7780979112112380027NAA25ENSG00000111300.52.389E-60.01166799gtex_brain_putamen_basal
rs7720439112112391876NAA25ENSG00000111300.52.389E-60.01154950gtex_brain_putamen_basal
rs1257819512112393934NAA25ENSG00000111300.52.389E-60.01152892gtex_brain_putamen_basal
rs1257979912112397887NAA25ENSG00000111300.52.389E-60.01148939gtex_brain_putamen_basal
rs1242368912112403135NAA25ENSG00000111300.52.389E-60.01143691gtex_brain_putamen_basal
rs1242369912112403161NAA25ENSG00000111300.55.469E-60.01143665gtex_brain_putamen_basal
rs1242631212112406749NAA25ENSG00000111300.52.389E-60.01140077gtex_brain_putamen_basal
rs8010497412112427796NAA25ENSG00000111300.52.389E-60.01119030gtex_brain_putamen_basal
rs7874595812112428171NAA25ENSG00000111300.52.389E-60.01118655gtex_brain_putamen_basal
rs5792985712112433556NAA25ENSG00000111300.52.389E-60.01113270gtex_brain_putamen_basal
rs6099843912112445969NAA25ENSG00000111300.52.389E-60.01100857gtex_brain_putamen_basal
rs7927189812112454619NAA25ENSG00000111300.52.916E-60.0192207gtex_brain_putamen_basal
rs7976157912112458885NAA25ENSG00000111300.52.389E-60.0187941gtex_brain_putamen_basal
rs7883190712112474664NAA25ENSG00000111300.52.861E-60.0172162gtex_brain_putamen_basal
rs7477844212112485072NAA25ENSG00000111300.55.469E-60.0161754gtex_brain_putamen_basal
rs8019021812112500687NAA25ENSG00000111300.52.389E-60.0146139gtex_brain_putamen_basal
rs1021971612112503474NAA25ENSG00000111300.52.389E-60.0143352gtex_brain_putamen_basal
rs5888697212112509281NAA25ENSG00000111300.55.465E-60.0137545gtex_brain_putamen_basal
rs7717608412112515312NAA25ENSG00000111300.52.389E-60.0131514gtex_brain_putamen_basal
rs7463682112112515912NAA25ENSG00000111300.52.389E-60.0130914gtex_brain_putamen_basal
rs7886639612112522346NAA25ENSG00000111300.52.389E-60.0124480gtex_brain_putamen_basal
rs1242294112112537738NAA25ENSG00000111300.52.389E-60.019088gtex_brain_putamen_basal
rs7954037212112538713NAA25ENSG00000111300.52.389E-60.018113gtex_brain_putamen_basal
rs7771018912112557759NAA25ENSG00000111300.52.389E-60.01-10933gtex_brain_putamen_basal
rs7728827712112582088NAA25ENSG00000111300.53.764E-60.01-35262gtex_brain_putamen_basal
rs6054997412112591821NAA25ENSG00000111300.51.898E-60.01-44995gtex_brain_putamen_basal
rs19997272012112593868NAA25ENSG00000111300.52.392E-60.01-47042gtex_brain_putamen_basal
rs1242718512112597274NAA25ENSG00000111300.52.025E-60.01-50448gtex_brain_putamen_basal
rs351912112598321NAA25ENSG00000111300.52.389E-60.01-51495gtex_brain_putamen_basal
rs383063312112599935NAA25ENSG00000111300.52.389E-60.01-53109gtex_brain_putamen_basal
rs229343212112601808NAA25ENSG00000111300.52.242E-60.01-54982gtex_brain_putamen_basal
rs20040057712112608316NAA25ENSG00000111300.52.392E-60.01-61490gtex_brain_putamen_basal
rs1258042812112615377NAA25ENSG00000111300.51.287E-60.01-68551gtex_brain_putamen_basal
rs1257933612112615538NAA25ENSG00000111300.52.389E-60.01-68712gtex_brain_putamen_basal
rs1242357212112615919NAA25ENSG00000111300.52.389E-60.01-69093gtex_brain_putamen_basal
rs7418704912112617918NAA25ENSG00000111300.52.389E-60.01-71092gtex_brain_putamen_basal
rs374199312112621886NAA25ENSG00000111300.52.389E-60.01-75060gtex_brain_putamen_basal
rs1694190912112626224NAA25ENSG00000111300.52.389E-60.01-79398gtex_brain_putamen_basal
rs5786667312112633304NAA25ENSG00000111300.52.389E-60.01-86478gtex_brain_putamen_basal
rs7752265412112635191NAA25ENSG00000111300.52.389E-60.01-88365gtex_brain_putamen_basal
rs1242326812112641707NAA25ENSG00000111300.52.389E-60.01-94881gtex_brain_putamen_basal
rs6008229312112661269NAA25ENSG00000111300.52.391E-60.01-114443gtex_brain_putamen_basal
rs1257985112112668755NAA25ENSG00000111300.52.389E-60.01-121929gtex_brain_putamen_basal
rs1257912312112845843NAA25ENSG00000111300.52.389E-60.01-299017gtex_brain_putamen_basal
rs7840104512112876736NAA25ENSG00000111300.52.389E-60.01-329910gtex_brain_putamen_basal
rs1106630812112881996NAA25ENSG00000111300.52.389E-60.01-335170gtex_brain_putamen_basal
rs1242319012112909340NAA25ENSG00000111300.52.389E-60.01-362514gtex_brain_putamen_basal
rs6063306812112938755NAA25ENSG00000111300.52.389E-60.01-391929gtex_brain_putamen_basal
rs1085004312112957138NAA25ENSG00000111300.56.482E-60.01-410312gtex_brain_putamen_basal
rs1085004512112959096NAA25ENSG00000111300.56.476E-60.01-412270gtex_brain_putamen_basal
rs1106633012112960013NAA25ENSG00000111300.56.476E-60.01-413187gtex_brain_putamen_basal
rs289139712112961447NAA25ENSG00000111300.56.476E-60.01-414621gtex_brain_putamen_basal
rs1085004712112964652NAA25ENSG00000111300.57.152E-60.01-417826gtex_brain_putamen_basal
rs580094812112964757NAA25ENSG00000111300.56.476E-60.01-417931gtex_brain_putamen_basal
rs238399912112964844NAA25ENSG00000111300.56.476E-60.01-418018gtex_brain_putamen_basal
rs1085004812112965801NAA25ENSG00000111300.51.229E-60.01-418975gtex_brain_putamen_basal
rs1106634412112991832NAA25ENSG00000111300.57.695E-60.01-445006gtex_brain_putamen_basal
rs476790812113000783NAA25ENSG00000111300.57.129E-60.01-453957gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL UP 285181All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL UP 7350All SZGR 2.0 genes in this pathway
HOOI ST7 TARGETS DN 12378All SZGR 2.0 genes in this pathway
WANG LMO4 TARGETS UP 372227All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY UP 430232All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375806All SZGR 2.0 genes in this pathway
WEI MYCN TARGETS WITH E BOX 795478All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR 681420All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR DN 911527All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR DN 1011592All SZGR 2.0 genes in this pathway
MONNIER POSTRADIATION TUMOR ESCAPE UP 393244All SZGR 2.0 genes in this pathway
KARLSSON TGFB1 TARGETS UP 12778All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882538All SZGR 2.0 genes in this pathway
PURBEY TARGETS OF CTBP1 NOT SATB1 DN 448282All SZGR 2.0 genes in this pathway