Summary ?
GeneID80152
SymbolCENPT
SynonymsC16orf56|CENP-T
Descriptioncentromere protein T
ReferenceMIM:611510|HGNC:HGNC:25787|Ensembl:ENSG00000102901|Vega:OTTHUMG00000173071
Gene typeprotein-coding
Map location16q22.1
Pascal p-value0.001
Sherlock p-value0.065
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs16829545chr2151977407CENPT801520.07trans
rs3845734chr2171125572CENPT801520.19trans
rs17104720chr1477127308CENPT801520.18trans
rs16955618chr1529937543CENPT801527.495E-5trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MRPL520.920.84
TCEB20.900.83
BLOC1S10.900.73
AP000350.60.890.79
AC009171.10.880.83
POLR2I0.880.76
TIMM8B0.870.81
CHCHD50.860.78
NDUFA110.860.78
NDUFB70.850.77
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MYH9-0.48-0.46
COBLL1-0.47-0.56
WNK1-0.46-0.55
SYNM-0.46-0.60
FLT1-0.46-0.62
GPR116-0.45-0.54
DST-0.45-0.52
UTRN-0.45-0.54
PTPN11-0.45-0.43
PK4P-0.45-0.54

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME CELL CYCLE 421253All SZGR 2.0 genes in this pathway
REACTOME CELL CYCLE MITOTIC 325185All SZGR 2.0 genes in this pathway
REACTOME MITOTIC M M G1 PHASES 17298All SZGR 2.0 genes in this pathway
REACTOME DNA REPLICATION 192110All SZGR 2.0 genes in this pathway
REACTOME MITOTIC PROMETAPHASE 8751All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142669All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP 612367All SZGR 2.0 genes in this pathway
MOHANKUMAR TLX1 TARGETS UP 414287All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS DN 261155All SZGR 2.0 genes in this pathway
XU GH1 EXOGENOUS TARGETS UP 8550All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER GOOD SURVIVAL A12 317177All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP 570339All SZGR 2.0 genes in this pathway
YANG BCL3 TARGETS UP 364236All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725838All SZGR 2.0 genes in this pathway