Gene Page: RND2
Summary ?
| GeneID | 8153 |
| Symbol | RND2 |
| Synonyms | ARHN|RHO7|RhoN |
| Description | Rho family GTPase 2 |
| Reference | MIM:601555|HGNC:HGNC:18315|Ensembl:ENSG00000108830|HPRD:03332|Vega:OTTHUMG00000180817 |
| Gene type | protein-coding |
| Map location | 17q21 |
| Pascal p-value | 0.017 |
| Sherlock p-value | 0.731 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CAMSAP1L1 | 0.89 | 0.95 |
| FAM160B1 | 0.89 | 0.95 |
| GNAQ | 0.87 | 0.94 |
| ZYG11B | 0.87 | 0.94 |
| AGL | 0.87 | 0.90 |
| ZBTB44 | 0.86 | 0.93 |
| MTMR9 | 0.86 | 0.94 |
| SCAMP1 | 0.86 | 0.92 |
| FEM1B | 0.86 | 0.95 |
| ATP13A3 | 0.86 | 0.94 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FXYD1 | -0.65 | -0.76 |
| MT-CO2 | -0.63 | -0.75 |
| AF347015.31 | -0.62 | -0.73 |
| HIGD1B | -0.61 | -0.74 |
| HSD17B14 | -0.61 | -0.69 |
| AF347015.33 | -0.61 | -0.69 |
| MT-CYB | -0.60 | -0.70 |
| AC021016.1 | -0.60 | -0.70 |
| TLCD1 | -0.60 | -0.70 |
| AF347015.8 | -0.60 | -0.73 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KIM RESPONSE TO TSA AND DECITABINE UP | 129 | 73 | All SZGR 2.0 genes in this pathway |
| CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 DN | 391 | 222 | All SZGR 2.0 genes in this pathway |
| BERENJENO ROCK SIGNALING NOT VIA RHOA UP | 29 | 21 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS NEUROEPITHELIUM DN | 164 | 111 | All SZGR 2.0 genes in this pathway |
| COWLING MYCN TARGETS | 43 | 27 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 16HR UP | 225 | 139 | All SZGR 2.0 genes in this pathway |
| DOUGLAS BMI1 TARGETS UP | 566 | 371 | All SZGR 2.0 genes in this pathway |
| LEIN PONS MARKERS | 89 | 59 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY E2F4 UNSTIMULATED | 728 | 415 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER RELAPSE IN LIVER DN | 10 | 9 | All SZGR 2.0 genes in this pathway |
| ICHIBA GRAFT VERSUS HOST DISEASE 35D UP | 131 | 79 | All SZGR 2.0 genes in this pathway |
| LEE BMP2 TARGETS UP | 745 | 475 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| ALFANO MYC TARGETS | 239 | 156 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |