Gene Page: CCDC130
Summary ?
GeneID | 81576 |
Symbol | CCDC130 |
Synonyms | - |
Description | coiled-coil domain containing 130 |
Reference | HGNC:HGNC:28118|Ensembl:ENSG00000104957|HPRD:11304|Vega:OTTHUMG00000180837 |
Gene type | protein-coding |
Map location | 19p13.2 |
Pascal p-value | 0.026 |
Sherlock p-value | 0.035 |
Fetal beta | 0.344 |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
Top 10 positively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
ZNF131 | 0.93 | 0.93 |
ZNF510 | 0.92 | 0.93 |
KIAA1429 | 0.92 | 0.93 |
ZNF644 | 0.92 | 0.93 |
ZNF420 | 0.92 | 0.93 |
ZNF583 | 0.92 | 0.93 |
DIS3 | 0.92 | 0.92 |
VEZT | 0.92 | 0.93 |
DDX20 | 0.92 | 0.93 |
CRNKL1 | 0.92 | 0.92 |
Top 10 negatively co-expressed genes | ||
Gene | Pearson's Correlation | Spearman's Correlation |
MT-CO2 | -0.77 | -0.88 |
AF347015.31 | -0.76 | -0.86 |
AF347015.33 | -0.76 | -0.86 |
AF347015.27 | -0.76 | -0.85 |
AF347015.8 | -0.75 | -0.87 |
MT-CYB | -0.75 | -0.85 |
FXYD1 | -0.74 | -0.86 |
AF347015.15 | -0.73 | -0.85 |
HLA-F | -0.71 | -0.77 |
IFI27 | -0.71 | -0.83 |
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP | 953 | 554 | All SZGR 2.0 genes in this pathway |
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
STEIN ESRRA TARGETS UP | 388 | 234 | All SZGR 2.0 genes in this pathway |
MITSIADES RESPONSE TO APLIDIN UP | 439 | 257 | All SZGR 2.0 genes in this pathway |
STEIN ESRRA TARGETS | 535 | 325 | All SZGR 2.0 genes in this pathway |
BRUINS UVC RESPONSE EARLY LATE | 317 | 190 | All SZGR 2.0 genes in this pathway |