Gene Page: GFOD2
Summary ?
| GeneID | 81577 |
| Symbol | GFOD2 |
| Synonyms | - |
| Description | glucose-fructose oxidoreductase domain containing 2 |
| Reference | HGNC:HGNC:28159|Ensembl:ENSG00000141098|HPRD:14419|Vega:OTTHUMG00000137537 |
| Gene type | protein-coding |
| Map location | 16q22.1 |
| Pascal p-value | 0.012 |
| Sherlock p-value | 0.493 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs16829545 | chr2 | 151977407 | GFOD2 | 81577 | 0.12 | trans | ||
| rs16955618 | chr15 | 29937543 | GFOD2 | 81577 | 0 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZNF225 | 0.86 | 0.87 |
| ESCO1 | 0.85 | 0.86 |
| ZNF568 | 0.84 | 0.86 |
| ZNF570 | 0.84 | 0.88 |
| ZNF615 | 0.84 | 0.86 |
| NOL8 | 0.84 | 0.85 |
| TTF1 | 0.84 | 0.84 |
| ZNF320 | 0.83 | 0.85 |
| ZNF182 | 0.83 | 0.85 |
| ZNF354B | 0.83 | 0.84 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.68 | -0.76 |
| MT-CO2 | -0.66 | -0.74 |
| AF347015.27 | -0.66 | -0.72 |
| IFI27 | -0.66 | -0.76 |
| MT-CYB | -0.65 | -0.73 |
| HIGD1B | -0.64 | -0.75 |
| AF347015.8 | -0.64 | -0.72 |
| AF347015.33 | -0.63 | -0.70 |
| AF347015.15 | -0.63 | -0.71 |
| HSD17B14 | -0.62 | -0.69 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
| WANG ESOPHAGUS CANCER VS NORMAL DN | 101 | 66 | All SZGR 2.0 genes in this pathway |
| TERAMOTO OPN TARGETS CLUSTER 1 | 13 | 10 | All SZGR 2.0 genes in this pathway |
| WANG METASTASIS OF BREAST CANCER ESR1 DN | 30 | 18 | All SZGR 2.0 genes in this pathway |
| LU EZH2 TARGETS UP | 295 | 155 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION UP | 570 | 339 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |