Gene Page: FAHD1
Summary ?
GeneID | 81889 |
Symbol | FAHD1 |
Synonyms | C16orf36|YISKL |
Description | fumarylacetoacetate hydrolase domain containing 1 |
Reference | MIM:616320|HGNC:HGNC:14169|Ensembl:ENSG00000180185|HPRD:13286|Vega:OTTHUMG00000128663 |
Gene type | protein-coding |
Map location | 16p13.3 |
Pascal p-value | 0.009 |
Sherlock p-value | 0.644 |
eGene | Caudate basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 1 |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
---|---|---|---|---|---|---|---|
cg06782493 | 16 | 1876874 | HAGH;FAHD1 | 1.97E-5 | -0.24 | 0.016 | DMG:Wockner_2014 |
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs3848346 | chr16 | 1889820 | FAHD1 | 81889 | 0.01 | cis | ||
rs3848348 | chr16 | 1890055 | FAHD1 | 81889 | 0 | cis | ||
rs1742419 | chr16 | 1901808 | FAHD1 | 81889 | 0.11 | cis | ||
rs1625393 | chr16 | 1901892 | FAHD1 | 81889 | 0.02 | cis | ||
rs1657117 | chr16 | 1903650 | FAHD1 | 81889 | 0.02 | cis | ||
rs7199384 | chr16 | 1904586 | FAHD1 | 81889 | 0.05 | cis | ||
rs453494 | chr16 | 1916102 | FAHD1 | 81889 | 0.03 | cis | ||
rs1657094 | chr16 | 1920628 | FAHD1 | 81889 | 0.01 | cis | ||
rs1657095 | chr16 | 1920677 | FAHD1 | 81889 | 0.1 | cis | ||
rs2917523 | chr16 | 1920739 | FAHD1 | 81889 | 0 | cis | ||
rs2974856 | chr16 | 1920756 | FAHD1 | 81889 | 0.08 | cis | ||
rs2982235 | chr16 | 1920791 | FAHD1 | 81889 | 0.02 | cis | ||
rs911392 | chr16 | 1947258 | FAHD1 | 81889 | 0.02 | cis | ||
rs1742464 | chr16 | 1947334 | FAHD1 | 81889 | 0.03 | cis | ||
rs2982447 | chr16 | 1947412 | FAHD1 | 81889 | 0.05 | cis | ||
rs2917523 | chr16 | 1920739 | FAHD1 | 81889 | 0.13 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
WEI MYCN TARGETS WITH E BOX | 795 | 478 | All SZGR 2.0 genes in this pathway |
NIKOLSKY BREAST CANCER 16P13 AMPLICON | 120 | 49 | All SZGR 2.0 genes in this pathway |
JOHNSTONE PARVB TARGETS 3 UP | 430 | 288 | All SZGR 2.0 genes in this pathway |
FORTSCHEGGER PHF8 TARGETS DN | 784 | 464 | All SZGR 2.0 genes in this pathway |