Summary ?
GeneID83697
SymbolSLC4A9
SynonymsAE4
Descriptionsolute carrier family 4 member 9
ReferenceMIM:610207|HGNC:HGNC:11035|Ensembl:ENSG00000113073|HPRD:15393|Vega:OTTHUMG00000163352
Gene typeprotein-coding
Map location5q31
Pascal p-value5.253E-4
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GSMA_IGenome scan meta-analysisPsr: 0.0032 

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10994209chr1061877705SLC4A9836970.19trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ANKMY10.790.74
CCDC650.750.66
LRRC480.750.70
GLB1L0.740.62
TSNAXIP10.730.63
WDR660.730.62
DNAH20.730.70
C2orf810.730.68
GAS2L20.720.62
CCDC400.720.63
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MT-CO2-0.45-0.48
AF347015.31-0.45-0.49
AF347015.21-0.44-0.53
AF347015.8-0.44-0.47
AF347015.2-0.43-0.47
AF347015.27-0.43-0.47
AF347015.33-0.42-0.44
MT-CYB-0.42-0.45
MT-ATP8-0.41-0.49
AF347015.15-0.41-0.43

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005452inorganic anion exchanger activityIEA-
GO:0005215transporter activityIEA-
GO:0008509anion transmembrane transporter activityIEA-
GO:0015297antiporter activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006820anion transportIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0016020membraneIEA-
GO:0016021integral to membraneIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES 413270All SZGR 2.0 genes in this pathway
REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT 241157All SZGR 2.0 genes in this pathway
REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES 9465All SZGR 2.0 genes in this pathway
MIKKELSEN ES LCP WITH H3K4ME3 14280All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857456All SZGR 2.0 genes in this pathway
DELACROIX RAR BOUND ES 462273All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725838All SZGR 2.0 genes in this pathway