Gene Page: MED10

Summary ?
GeneID84246
SymbolMED10
SynonymsL6|NUT2|TRG20
Descriptionmediator complex subunit 10
ReferenceMIM:612382|HGNC:HGNC:28760|Ensembl:ENSG00000133398|HPRD:14680|Vega:OTTHUMG00000161682
Gene typeprotein-coding
Map location5p15.31
Pascal p-value0.524
Sherlock p-value0.707
eGeneCerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCNCCycCcyclin CAffinity Capture-MSBioGRID15175163 
CDC2L6CDK11 | KIAA1028 | bA346C16.3cell division cycle 2-like 6 (CDK8-like)Affinity Capture-MSBioGRID15175163 
CDK8K35 | MGC126074 | MGC126075cyclin-dependent kinase 8Affinity Capture-MS
Affinity Capture-Western		BioGRID10198638 |15175163 
MED1CRSP1 | CRSP200 | DRIP205 | DRIP230 | MGC71488 | PBP | PPARBP | PPARGBP | RB18A | TRAP220 | TRIP2mediator complex subunit 1Affinity Capture-MS
Affinity Capture-Western		BioGRID14638676 |15175163 
MED10L6 | MGC5309 | NUT2 | TRG20mediator complex subunit 10Affinity Capture-MSBioGRID15175163 
MED11HSPC296 | MGC88387mediator complex subunit 11Affinity Capture-MS
Affinity Capture-Western		BioGRID12584197 |14576168 
|14638676 |15175163 
MED12CAGH45 | HOPA | KIAA0192 | OPA1 | TNRC11 | TRAP230mediator complex subunit 12Affinity Capture-MS
Affinity Capture-Western		BioGRID15175163 
MED13ARC250 | DRIP250 | HSPC221 | KIAA0593 | THRAP1 | TRAP240mediator complex subunit 13Affinity Capture-MSBioGRID15175163 
MED13LDKFZp781D0112 | FLJ21627 | KIAA1025 | PROSIT240 | THRAP2 | TRAP240Lmediator complex subunit 13-likeAffinity Capture-MSBioGRID15175163 
MED14CRSP150 | CRSP2 | CSRP | CXorf4 | DRIP150 | EXLM1 | MGC104513 | RGR1 | TRAP170mediator complex subunit 14Affinity Capture-MSBioGRID15175163 
MED15ARC105 | CAG7A | CTG7A | DKFZp686A2214 | DKFZp762B1216 | FLJ42282 | FLJ42935 | PCQAP | TIG-1 | TIG1 | TNRC7mediator complex subunit 15Affinity Capture-MSBioGRID15175163 
MED16DRIP92 | THRAP5 | TRAP95mediator complex subunit 16Affinity Capture-MSBioGRID15175163 
MED17CRSP6 | CRSP77 | DRIP80 | FLJ10812 | TRAP80mediator complex subunit 17Affinity Capture-MS
Affinity Capture-Western		BioGRID12584197 |14576168 
|14638676 |15175163 
MED18FLJ20045 | p28bmediator complex subunit 18Affinity Capture-MS
Affinity Capture-Western		BioGRID12584197 |14576168 
|14638676 |15175163 
MED19DT2P1G7 | LCMR1mediator complex subunit 19Affinity Capture-MS
Affinity Capture-Western		BioGRID12584197 |14638676 
|15175163 
MED20DKFZp586D2223 | MGC29869 | PRO0213 | TRFPmediator complex subunit 20Affinity Capture-MS
Affinity Capture-Western		BioGRID14576168 |15175163 
MED21SRB7 | SURB7mediator complex subunit 21Affinity Capture-MSBioGRID15175163 
MED22MED24 | MGC48682 | SURF5mediator complex subunit 22Affinity Capture-MSBioGRID12584197 |15175163 
MED23CRSP130 | CRSP133 | CRSP3 | DKFZp434H0117 | DRIP130 | SUR2mediator complex subunit 23Affinity Capture-MSBioGRID15175163 
MED24ARC100 | CRSP100 | CRSP4 | DRIP100 | KIAA0130 | MGC8748 | THRAP4 | TRAP100mediator complex subunit 24Affinity Capture-MSBioGRID15175163 
MED25ACID1 | ARC92 | DKFZp434K0512 | MGC70671 | P78 | PTOV2 | TCBAP0758mediator complex subunit 25Affinity Capture-MSBioGRID15175163 
MED26CRSP7 | CRSP70mediator complex subunit 26Affinity Capture-MSBioGRID15175163 
MED27CRAP34 | CRSP34 | CRSP8 | MGC11274 | TRAP37mediator complex subunit 27Affinity Capture-MSBioGRID15175163 
MED281500003D12Rik | DKFZp434N185 | EG1 | magicinmediator complex subunit 28Affinity Capture-MSBioGRID15175163 
MED29DKFZp434H247 | IXLmediator complex subunit 29Affinity Capture-MS
Affinity Capture-Western		BioGRID14576168 |14638676 
|15175163 
MED30MGC9890 | THRAP6 | TRAP25mediator complex subunit 30Affinity Capture-MSBioGRID15175163 
MED313110004H13Rik | CGI-125 | FLJ27436 | FLJ36714 | Soh1mediator complex subunit 31Affinity Capture-MS
Affinity Capture-Western		BioGRID14576168 |15175163 
MED4DRIP36 | FLJ10956 | HSPC126 | RP11-90M2.2 | TRAP36 | VDRIPmediator complex subunit 4Affinity Capture-MS
Affinity Capture-Western		BioGRID14638676 |15175163 
MED6NY-REN-28mediator complex subunit 6Affinity Capture-MS
Affinity Capture-Western		BioGRID12584197 |14576168 
|15175163 
MED7CRSP33 | CRSP9 | MGC12284mediator complex subunit 7Affinity Capture-MSBioGRID15175163 
MED8ARC32 | MGC17544 | MGC19641mediator complex subunit 8Affinity Capture-MS
Affinity Capture-Western		BioGRID12584197 |14576168 
|14638676 |15175163 
MED9FLJ10193 | MED25 | MGC138234mediator complex subunit 9Affinity Capture-MSBioGRID15175163 
MOBKL32C4D | CGI-95 | MGC12264 | MOB1 | MOB3 | PREI3MOB1, Mps One Binder kinase activator-like 3 (yeast)Two-hybridBioGRID16169070 
POLR2AMGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1polymerase (RNA) II (DNA directed) polypeptide A, 220kDaAffinity Capture-MS
Affinity Capture-Western		BioGRID15175163 
POLR2BPOL2RB | RPB2 | hRPB140 | hsRPB2polymerase (RNA) II (DNA directed) polypeptide B, 140kDaAffinity Capture-MSBioGRID15175163 
POLR2CRPB3 | RPB31 | hRPB33 | hsRPB3polymerase (RNA) II (DNA directed) polypeptide C, 33kDaAffinity Capture-MSBioGRID15175163 
POLR2DHSRBP4 | HSRPB4 | RBP4polymerase (RNA) II (DNA directed) polypeptide DAffinity Capture-MSBioGRID15175163 
POLR2ERPABC1 | RPB5 | XAP4 | hRPB25 | hsRPB5polymerase (RNA) II (DNA directed) polypeptide E, 25kDaAffinity Capture-MSBioGRID15175163 
POLR2FHRBP14.4 | POLRF | RPABC2 | RPB14.4 | RPB6polymerase (RNA) II (DNA directed) polypeptide FAffinity Capture-MSBioGRID15175163 
POLR2GMGC138367 | MGC138369 | RPB7 | hRPB19 | hsRPB7polymerase (RNA) II (DNA directed) polypeptide GAffinity Capture-MSBioGRID15175163 
POLR2HRPABC3 | RPB17 | RPB8 | hsRPB8polymerase (RNA) II (DNA directed) polypeptide HAffinity Capture-MSBioGRID15175163 
POLR2IRPB9 | hRPB14.5polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDaAffinity Capture-MSBioGRID15175163 
POLR2JMGC71910 | POLR2J1 | RPB11 | RPB11A | RPB11m | hRPB14polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDaAffinity Capture-MSBioGRID15175163 
POLR2KABC10-alpha | RPABC4 | RPB10alpha | RPB12 | RPB7.0 | hRPB7.0 | hsRPB10apolymerase (RNA) II (DNA directed) polypeptide K, 7.0kDaAffinity Capture-MSBioGRID15175163 
POLR2LRBP10 | RPABC5 | RPB10 | RPB10beta | RPB7.6 | hRPB7.6 | hsRPB10bpolymerase (RNA) II (DNA directed) polypeptide L, 7.6kDaAffinity Capture-MSBioGRID15175163 


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME DEVELOPMENTAL BIOLOGY 396292All SZGR 2.0 genes in this pathway
REACTOME PPARA ACTIVATES GENE EXPRESSION 10472All SZGR 2.0 genes in this pathway
REACTOME GENERIC TRANSCRIPTION PATHWAY 352181All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS 478302All SZGR 2.0 genes in this pathway
REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM 168115All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 7253All SZGR 2.0 genes in this pathway
WANG LMO4 TARGETS DN 352225All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS UP 12672All SZGR 2.0 genes in this pathway
WEI MYCN TARGETS WITH E BOX 795478All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL AND BRAIN QTL TRANS 185114All SZGR 2.0 genes in this pathway
JIANG HYPOXIA NORMAL 311205All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP 307182All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE EARLY LATE 317190All SZGR 2.0 genes in this pathway
BAKKER FOXO3 TARGETS DN 187109All SZGR 2.0 genes in this pathway