Gene Page: ZNF282
Summary ?
| GeneID | 8427 |
| Symbol | ZNF282 |
| Synonyms | HUB1 |
| Description | zinc finger protein 282 |
| Reference | MIM:603397|HGNC:HGNC:13076|Ensembl:ENSG00000170265|HPRD:04549|Vega:OTTHUMG00000158974 |
| Gene type | protein-coding |
| Map location | 7q36.1 |
| Pascal p-value | 0.046 |
| Sherlock p-value | 0.838 |
| Support | Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MSH6 | 0.97 | 0.94 |
| SMAD4 | 0.96 | 0.95 |
| RBMX | 0.95 | 0.90 |
| NONO | 0.95 | 0.92 |
| SP3 | 0.95 | 0.93 |
| PDCL | 0.95 | 0.94 |
| RBBP4 | 0.95 | 0.89 |
| DHX15 | 0.95 | 0.95 |
| HNRNPF | 0.95 | 0.89 |
| STAG1 | 0.95 | 0.93 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.66 | -0.86 |
| HLA-F | -0.65 | -0.76 |
| FXYD1 | -0.65 | -0.87 |
| AF347015.31 | -0.65 | -0.85 |
| C5orf53 | -0.65 | -0.73 |
| AIFM3 | -0.65 | -0.77 |
| IFI27 | -0.65 | -0.85 |
| AF347015.33 | -0.64 | -0.84 |
| AF347015.27 | -0.64 | -0.82 |
| PTH1R | -0.64 | -0.74 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME GENERIC TRANSCRIPTION PATHWAY | 352 | 181 | All SZGR 2.0 genes in this pathway |
| TIEN INTESTINE PROBIOTICS 24HR DN | 214 | 133 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN DN | 1781 | 1082 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS UP | 811 | 508 | All SZGR 2.0 genes in this pathway |
| NGUYEN NOTCH1 TARGETS DN | 86 | 67 | All SZGR 2.0 genes in this pathway |
| SWEET LUNG CANCER KRAS UP | 491 | 316 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 AND SATB1 DN | 180 | 116 | All SZGR 2.0 genes in this pathway |