Gene Page: SPATA22
Summary ?
| GeneID | 84690 |
| Symbol | SPATA22 |
| Synonyms | NYD-SP20|NYDSP20 |
| Description | spermatogenesis associated 22 |
| Reference | HGNC:HGNC:30705|Ensembl:ENSG00000141255|HPRD:14862|Vega:OTTHUMG00000177609 |
| Gene type | protein-coding |
| Map location | 17p13.3 |
| Pascal p-value | 0.953 |
| Fetal beta | 0.086 |
| eGene | Cortex Nucleus accumbens basal ganglia |
| Support | CompositeSet |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DNM:Xu_2012 | Whole Exome Sequencing analysis | De novo mutations of 4 genes were identified by exome sequencing of 795 samples in this study |
Section I. Genetics and epigenetics annotation
DNM table
| Gene | Chromosome | Position | Ref | Alt | Transcript | AA change | Mutation type | Sift | CG46 | Trait | Study |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SPATA22 | chr17 | 3352372 | C | T | NM_001170695 NM_001170696 NM_001170697 NM_001170698 NM_001170699 NM_032598 | p.134R>Q p.91R>Q p.134R>Q p.134R>Q p.134R>Q p.134R>Q | missense missense missense missense missense missense | Schizophrenia | DNM:Xu_2012 |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| WEBER METHYLATED HCP IN FIBROBLAST DN | 42 | 22 | All SZGR 2.0 genes in this pathway |
| WEBER METHYLATED HCP IN SPERM UP | 20 | 13 | All SZGR 2.0 genes in this pathway |
| MIKKELSEN IPS HCP WITH H3 UNMETHYLATED | 80 | 50 | All SZGR 2.0 genes in this pathway |