Gene Page: PYROXD2

Summary ?
GeneID84795
SymbolPYROXD2
SynonymsC10orf33|FP3420
Descriptionpyridine nucleotide-disulphide oxidoreductase domain 2
ReferenceHGNC:HGNC:23517|Ensembl:ENSG00000119943|HPRD:12572|Vega:OTTHUMG00000018877
Gene typeprotein-coding
Map location10q24.2
Pascal p-value0.003
Sherlock p-value0.746
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cortex
Hippocampus
Hypothalamus
Myers' cis & trans
Meta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs4345897chr10100147059PYROXD2847950.02cis
rs2147897chr10100147812PYROXD2847950.04cis
rs4551689chr10100157592PYROXD2847950.05cis
rs7914401chr10100163927PYROXD2847950.12cis
rs2147901chr10100165495PYROXD2847950.15cis
rs1061437chr10100176153PYROXD2847950.15cis
rs1739chr10100176338PYROXD2847950.03cis
rs12129836chr148308456PYROXD2847950.19trans
rs2494067chr1108245614PYROXD2847950.19trans
rs10126993chrX35885796PYROXD2847950.17trans
rs4501739chrX35960848PYROXD2847950.06trans
rs1088308210100126295PYROXD2ENSG00000119943.64.454E-8048646gtex_brain_ba24
rs709665410100134036PYROXD2ENSG00000119943.62.04E-9040905gtex_brain_ba24
rs1118958110100137700PYROXD2ENSG00000119943.69.578E-10037241gtex_brain_ba24
rs1078641410100141027PYROXD2ENSG00000119943.63.103E-9033914gtex_brain_ba24
rs707565510100142068PYROXD2ENSG00000119943.62.01E-8032873gtex_brain_ba24
rs578727910100142677PYROXD2ENSG00000119943.61.965E-7032264gtex_brain_ba24
rs790526510100143193PYROXD2ENSG00000119943.62.995E-9031748gtex_brain_ba24
rs20054435710100144007PYROXD2ENSG00000119943.61.668E-8030934gtex_brain_ba24
rs1088308310100145913PYROXD2ENSG00000119943.63.381E-9029028gtex_brain_ba24
rs20203645510100146076PYROXD2ENSG00000119943.64.8E-7028865gtex_brain_ba24
rs1159886710100146084PYROXD2ENSG00000119943.65.583E-11028857gtex_brain_ba24
rs5966729610100146313PYROXD2ENSG00000119943.63.163E-8028628gtex_brain_ba24
rs229643810100146895PYROXD2ENSG00000119943.61.472E-8028046gtex_brain_ba24
rs434589710100147060PYROXD2ENSG00000119943.61.474E-8027881gtex_brain_ba24
rs440072110100147097PYROXD2ENSG00000119943.61.965E-7027844gtex_brain_ba24
rs218217010100147421PYROXD2ENSG00000119943.61.404E-8027520gtex_brain_ba24
rs214789710100147813PYROXD2ENSG00000119943.61.474E-8027128gtex_brain_ba24
rs218216910100148004PYROXD2ENSG00000119943.61.474E-8026937gtex_brain_ba24
rs453924210100148058PYROXD2ENSG00000119943.62.995E-9026883gtex_brain_ba24
rs214789610100148176PYROXD2ENSG00000119943.62.995E-9026765gtex_brain_ba24
rs214789510100148308PYROXD2ENSG00000119943.61.522E-8026633gtex_brain_ba24
rs218216810100148353PYROXD2ENSG00000119943.61.474E-8026588gtex_brain_ba24
rs791646910100148653PYROXD2ENSG00000119943.61.474E-8026288gtex_brain_ba24
rs75512610100148951PYROXD2ENSG00000119943.61.474E-8025990gtex_brain_ba24
rs107917910100149346PYROXD2ENSG00000119943.61.474E-8025595gtex_brain_ba24
rs227424710100150148PYROXD2ENSG00000119943.61.474E-8024793gtex_brain_ba24
rs1088308410100151189PYROXD2ENSG00000119943.61.474E-8023752gtex_brain_ba24
rs1078641510100151266PYROXD2ENSG00000119943.62.995E-9023675gtex_brain_ba24
rs94281410100151305PYROXD2ENSG00000119943.62.995E-9023636gtex_brain_ba24
rs709782410100151799PYROXD2ENSG00000119943.61.474E-8023142gtex_brain_ba24
rs708219210100151844PYROXD2ENSG00000119943.61.48E-8023097gtex_brain_ba24
rs658419110100152055PYROXD2ENSG00000119943.62.995E-9022886gtex_brain_ba24
rs658419210100152373PYROXD2ENSG00000119943.61.474E-8022568gtex_brain_ba24
rs1078641610100153600PYROXD2ENSG00000119943.62.98E-6021341gtex_brain_ba24
rs94281310100153608PYROXD2ENSG00000119943.62.991E-9021333gtex_brain_ba24
rs1078641710100153904PYROXD2ENSG00000119943.63.116E-6021037gtex_brain_ba24
rs1118958610100154096PYROXD2ENSG00000119943.62.98E-6020845gtex_brain_ba24
rs1159742510100154202PYROXD2ENSG00000119943.62.98E-6020739gtex_brain_ba24
rs1159742810100154247PYROXD2ENSG00000119943.62.98E-6020694gtex_brain_ba24
rs1118958710100154545PYROXD2ENSG00000119943.62.98E-6020396gtex_brain_ba24
rs1118958810100154551PYROXD2ENSG00000119943.62.98E-6020390gtex_brain_ba24
rs1118958910100154565PYROXD2ENSG00000119943.62.98E-6020376gtex_brain_ba24
rs1118959110100155296PYROXD2ENSG00000119943.61.446E-8019645gtex_brain_ba24
rs1088308510100155613PYROXD2ENSG00000119943.67.388E-7019328gtex_brain_ba24
rs1088308610100155743PYROXD2ENSG00000119943.62.98E-6019198gtex_brain_ba24
rs790755510100155810PYROXD2ENSG00000119943.62.98E-6019131gtex_brain_ba24
rs792420910100155927PYROXD2ENSG00000119943.62.98E-6019014gtex_brain_ba24
rs792430310100155963PYROXD2ENSG00000119943.62.98E-6018978gtex_brain_ba24
rs790831010100156227PYROXD2ENSG00000119943.62.98E-6018714gtex_brain_ba24
rs707221610100156853PYROXD2ENSG00000119943.62.995E-9018088gtex_brain_ba24
rs1088308710100156990PYROXD2ENSG00000119943.62.98E-6017951gtex_brain_ba24
rs1078641810100157368PYROXD2ENSG00000119943.62.98E-6017573gtex_brain_ba24
rs455168910100157593PYROXD2ENSG00000119943.67.388E-7017348gtex_brain_ba24
rs1181972910100157726PYROXD2ENSG00000119943.61.927E-6017215gtex_brain_ba24
rs709762510100158922PYROXD2ENSG00000119943.61.413E-6016019gtex_brain_ba24
rs448813310100159136PYROXD2ENSG00000119943.61.149E-9015805gtex_brain_ba24
rs658419410100160399PYROXD2ENSG00000119943.61.42E-7014542gtex_brain_ba24
rs1088308910100163120PYROXD2ENSG00000119943.61.01E-6011821gtex_brain_ba24
rs789735710100163597PYROXD2ENSG00000119943.62.718E-6011344gtex_brain_ba24
rs791440110100163928PYROXD2ENSG00000119943.66.028E-8011013gtex_brain_ba24
rs73334510100164215PYROXD2ENSG00000119943.66.028E-8010726gtex_brain_ba24
rs73334610100164325PYROXD2ENSG00000119943.63.303E-8010616gtex_brain_ba24
rs791510810100164441PYROXD2ENSG00000119943.61.032E-7010500gtex_brain_ba24
rs790157710100164442PYROXD2ENSG00000119943.61.032E-7010499gtex_brain_ba24
rs447437210100164571PYROXD2ENSG00000119943.66.02E-8010370gtex_brain_ba24
rs447586110100164989PYROXD2ENSG00000119943.66.02E-809952gtex_brain_ba24
rs214790110100165496PYROXD2ENSG00000119943.66.05E-809445gtex_brain_ba24
rs1073278210100166506PYROXD2ENSG00000119943.66.05E-808435gtex_brain_ba24
rs791097310100166732PYROXD2ENSG00000119943.66.05E-808209gtex_brain_ba24
rs791103610100167015PYROXD2ENSG00000119943.66.05E-807926gtex_brain_ba24
rs1088309010100167236PYROXD2ENSG00000119943.66.05E-807705gtex_brain_ba24
rs1088309110100167239PYROXD2ENSG00000119943.66.05E-807702gtex_brain_ba24
rs1088309210100167276PYROXD2ENSG00000119943.66.05E-807665gtex_brain_ba24
rs1276332610100167396PYROXD2ENSG00000119943.66.05E-807545gtex_brain_ba24
rs4552343210100167436PYROXD2ENSG00000119943.66.05E-807505gtex_brain_ba24
rs1276304410100167451PYROXD2ENSG00000119943.66.05E-807490gtex_brain_ba24
rs1276337910100167466PYROXD2ENSG00000119943.63.08E-807475gtex_brain_ba24
rs1276822710100167495PYROXD2ENSG00000119943.66.05E-807446gtex_brain_ba24
rs1276774010100167501PYROXD2ENSG00000119943.61.061E-707440gtex_brain_ba24
rs709167710100167553PYROXD2ENSG00000119943.64.426E-707388gtex_brain_ba24
rs709170910100167605PYROXD2ENSG00000119943.66.05E-807336gtex_brain_ba24
rs94281010100167860PYROXD2ENSG00000119943.62.694E-607081gtex_brain_ba24
rs94280910100168001PYROXD2ENSG00000119943.69.821E-806940gtex_brain_ba24
rs94280810100168102PYROXD2ENSG00000119943.66.05E-806839gtex_brain_ba24
rs94280710100168219PYROXD2ENSG00000119943.66.05E-806722gtex_brain_ba24
rs94280610100168248PYROXD2ENSG00000119943.66.05E-806693gtex_brain_ba24
rs578728310100168329PYROXD2ENSG00000119943.66.05E-806612gtex_brain_ba24
rs94280510100168372PYROXD2ENSG00000119943.66.05E-806569gtex_brain_ba24
rs94280410100168499PYROXD2ENSG00000119943.66.05E-806442gtex_brain_ba24
rs94280310100168631PYROXD2ENSG00000119943.66.05E-806310gtex_brain_ba24
rs6081372110100169013PYROXD2ENSG00000119943.62.011E-605928gtex_brain_ba24
rs1225993910100169021PYROXD2ENSG00000119943.66.05E-805920gtex_brain_ba24
rs978755010100169051PYROXD2ENSG00000119943.66.05E-805890gtex_brain_ba24
rs792372910100169465PYROXD2ENSG00000119943.66.05E-805476gtex_brain_ba24
rs980428510100169472PYROXD2ENSG00000119943.66.05E-805469gtex_brain_ba24
rs658419710100169685PYROXD2ENSG00000119943.61.123E-705256gtex_brain_ba24
rs658419810100169906PYROXD2ENSG00000119943.66.05E-805035gtex_brain_ba24
rs658419910100169983PYROXD2ENSG00000119943.66.05E-804958gtex_brain_ba24
rs658420010100170037PYROXD2ENSG00000119943.66.05E-804904gtex_brain_ba24
rs658420110100170209PYROXD2ENSG00000119943.66.05E-804732gtex_brain_ba24
rs658420210100170383PYROXD2ENSG00000119943.66.05E-804558gtex_brain_ba24
rs789682810100170507PYROXD2ENSG00000119943.62.694E-604434gtex_brain_ba24
rs381414010100170762PYROXD2ENSG00000119943.66.05E-804179gtex_brain_ba24
rs381414110100171028PYROXD2ENSG00000119943.61.034E-603913gtex_brain_ba24
rs381414210100171104PYROXD2ENSG00000119943.66.05E-803837gtex_brain_ba24
rs382985310100171174PYROXD2ENSG00000119943.66.05E-803767gtex_brain_ba24
rs1074872810100171198PYROXD2ENSG00000119943.66.05E-803743gtex_brain_ba24
rs1074872910100171371PYROXD2ENSG00000119943.66.062E-803570gtex_brain_ba24
rs1074873010100171440PYROXD2ENSG00000119943.66.062E-803501gtex_brain_ba24
rs790913110100171471PYROXD2ENSG00000119943.62.699E-603470gtex_brain_ba24
rs1073612910100171571PYROXD2ENSG00000119943.66.062E-803370gtex_brain_ba24
rs790982210100172035PYROXD2ENSG00000119943.66.074E-802906gtex_brain_ba24
rs791001410100172110PYROXD2ENSG00000119943.66.063E-802831gtex_brain_ba24
rs791024710100172252PYROXD2ENSG00000119943.66.074E-802689gtex_brain_ba24
rs791354110100172479PYROXD2ENSG00000119943.66.074E-802462gtex_brain_ba24
rs425831110100173328PYROXD2ENSG00000119943.67.103E-801613gtex_brain_ba24
rs658420310100173428PYROXD2ENSG00000119943.64.494E-801513gtex_brain_ba24
rs658420410100173580PYROXD2ENSG00000119943.66.086E-801361gtex_brain_ba24
rs658420510100173806PYROXD2ENSG00000119943.66.098E-801135gtex_brain_ba24
rs578728410100174167PYROXD2ENSG00000119943.66.098E-80774gtex_brain_ba24
rs375060110100174561PYROXD2ENSG00000119943.66.098E-80380gtex_brain_ba24
rs214790010100174721PYROXD2ENSG00000119943.66.11E-80220gtex_brain_ba24
rs227424610100175060PYROXD2ENSG00000119943.66.11E-80-119gtex_brain_ba24
rs227424510100175082PYROXD2ENSG00000119943.66.11E-80-141gtex_brain_ba24
rs227424410100175218PYROXD2ENSG00000119943.66.11E-80-277gtex_brain_ba24
rs227424310100175267PYROXD2ENSG00000119943.66.11E-80-326gtex_brain_ba24
rs818129210100175477PYROXD2ENSG00000119943.66.135E-80-536gtex_brain_ba24
rs375060310100175536PYROXD2ENSG00000119943.66.197E-80-595gtex_brain_ba24
rs375060510100175654PYROXD2ENSG00000119943.61.034E-60-713gtex_brain_ba24
rs383002510100176104PYROXD2ENSG00000119943.67.49E-70-1163gtex_brain_ba24
rs383002410100176106PYROXD2ENSG00000119943.65.503E-70-1165gtex_brain_ba24
rs106143710100176154PYROXD2ENSG00000119943.62.551E-70-1213gtex_brain_ba24
rs792114610100186601PYROXD2ENSG00000119943.68.387E-80-11660gtex_brain_ba24

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 8D DN 205127All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 10D DN 14290All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 16D DN 14383All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 DN 229142All SZGR 2.0 genes in this pathway
HEIDENBLAD AMPLICON 8Q24 DN 4628All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS UP 266171All SZGR 2.0 genes in this pathway
SUZUKI RESPONSE TO TSA AND DECITABINE 1A 2316All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 1 528324All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354216All SZGR 2.0 genes in this pathway
CHANG CORE SERUM RESPONSE DN 209137All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718401All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL DN 428246All SZGR 2.0 genes in this pathway