Gene Page: JRK
Summary ?
| GeneID | 8629 |
| Symbol | JRK |
| Synonyms | JH8|jerky |
| Description | Jrk helix-turn-helix protein |
| Reference | MIM:603210|HGNC:HGNC:6199|Ensembl:ENSG00000234616|HPRD:04442|Vega:OTTHUMG00000160911 |
| Gene type | protein-coding |
| Map location | 8q24.3 |
| Pascal p-value | 6.398E-6 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| HLA-B | 0.57 | 0.61 |
| GGT5 | 0.56 | 0.60 |
| DEGS2 | 0.54 | 0.61 |
| HLA-C | 0.54 | 0.53 |
| C20orf160 | 0.53 | 0.55 |
| CLEC14A | 0.53 | 0.57 |
| GAS2L1 | 0.52 | 0.58 |
| LSR | 0.52 | 0.58 |
| UNC93B3 | 0.52 | 0.57 |
| TMEM204 | 0.52 | 0.58 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CLK1 | -0.47 | -0.60 |
| CCAR1 | -0.46 | -0.51 |
| POLG2 | -0.46 | -0.49 |
| ZNF433 | -0.46 | -0.46 |
| ZNF548 | -0.46 | -0.47 |
| ZNF586 | -0.46 | -0.47 |
| PRPF39 | -0.45 | -0.51 |
| ZNF285B | -0.45 | -0.45 |
| ZNF354B | -0.45 | -0.46 |
| ZNF211 | -0.45 | -0.44 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ZHOU INFLAMMATORY RESPONSE LIVE UP | 485 | 293 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE LPS UP | 431 | 237 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | 637 | 377 | All SZGR 2.0 genes in this pathway |
| LIAO METASTASIS | 539 | 324 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | 236 | 139 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED MODERATELY VS POORLY DN | 15 | 8 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 8Q23 Q24 AMPLICON | 157 | 87 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT UP | 390 | 242 | All SZGR 2.0 genes in this pathway |
| LEE AGING CEREBELLUM DN | 86 | 66 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| LINDSTEDT DENDRITIC CELL MATURATION B | 53 | 36 | All SZGR 2.0 genes in this pathway |
| YUAN ZNF143 PARTNERS | 22 | 15 | All SZGR 2.0 genes in this pathway |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | All SZGR 2.0 genes in this pathway |
| DELACROIX RARG BOUND MEF | 367 | 231 | All SZGR 2.0 genes in this pathway |
| PEDRIOLI MIR31 TARGETS UP | 221 | 120 | All SZGR 2.0 genes in this pathway |
| PHONG TNF RESPONSE VIA P38 COMPLETE | 227 | 151 | All SZGR 2.0 genes in this pathway |