| ABL1 | ABL | JTK7 | bcr/abl | c-ABL | p150 | v-abl | c-abl oncogene 1, receptor tyrosine kinase | - | HPRD,BioGRID | 12475393 |
| ARHGEF7 | BETA-PIX | COOL1 | DKFZp686C12170 | DKFZp761K1021 | KIAA0142 | KIAA0412 | Nbla10314 | P50 | P50BP | P85 | P85COOL1 | P85SPR | PAK3 | PIXB | Rho guanine nucleotide exchange factor (GEF) 7 | Two-hybrid | BioGRID | 12935897 |
| BCR | ALL | BCR-ABL1 | BCR1 | CML | D22S11 | D22S662 | FLJ16453 | PHL | breakpoint cluster region | Co-purification | BioGRID | 8641358 |
| BLK | MGC10442 | B lymphoid tyrosine kinase | - | HPRD | 8083187 |
| BTK | AGMX1 | AT | ATK | BPK | IMD1 | MGC126261 | MGC126262 | PSCTK1 | XLA | Bruton agammaglobulinemia tyrosine kinase | - | HPRD,BioGRID | 7629518 |10427990
|
| CD19 | B4 | MGC12802 | CD19 molecule | - | HPRD | 9178909 |
| CD2AP | CMS | DKFZp586H0519 | CD2-associated protein | CMS interacts with Cbl. This interaction was modeled on a demonstrated interaction between CMS from an unspecified species and human Cbl. | BIND | 15128873 |
| - | HPRD,BioGRID | 11067845 |
| CD5 | LEU1 | T1 | CD5 molecule | - | HPRD,BioGRID | 9603468 |
| CDKL2 | KKIAMRE | P56 | cyclin-dependent kinase-like 2 (CDC2-related kinase) | - | HPRD | 7721825 |
| CRK | CRKII | v-crk sarcoma virus CT10 oncogene homolog (avian) | Affinity Capture-Western | BioGRID | 9178909 |9461587
|
| - | HPRD | 8621483 |8662998
|
| CRKL | - | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | Affinity Capture-Western Reconstituted Complex | BioGRID | 9092574 |9162067 |9344843 |9461587 |9590251 |9820532 |10204582 |10907644 |11133830 |12244174
|
| - | HPRD | 9162067 |9590251 |12244174 |
| CSF1R | C-FMS | CD115 | CSFR | FIM2 | FMS | colony stimulating factor 1 receptor | - | HPRD,BioGRID | 11847211 |
| CSK | MGC117393 | c-src tyrosine kinase | - | HPRD,BioGRID | 11149930 |
| EGFR | ERBB | ERBB1 | HER1 | PIG61 | mENA | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | Affinity Capture-Western | BioGRID | 10086340 |12061819
|
| - | HPRD | 8662998 |
| An unspecified isoform of EGFR interacts with CBL. | BIND | 15735736 |
| c-Cbl ubiquitinates an unspecified isoform of EGFR. This interaction was modeled on a demonstrated interaction between c-Cbl and EGFR, both from an unspecified species. | BIND | 12234920 |
| EPHB6 | HEP | MGC129910 | MGC129911 | EPH receptor B6 | - | HPRD | 11713248 |
| FGR | FLJ43153 | MGC75096 | SRC2 | c-fgr | c-src2 | p55c-fgr | p58c-fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | - | HPRD,BioGRID | 12435267 |
| FLOT1 | - | flotillin 1 | - | HPRD,BioGRID | 11001060 |
| FRS2 | FRS2A | FRS2alpha | SNT | SNT-1 | SNT1 | fibroblast growth factor receptor substrate 2 | - | HPRD,BioGRID | 11997436 |
| FYN | MGC45350 | SLK | SYN | FYN oncogene related to SRC, FGR, YES | - | HPRD,BioGRID | 9535867 |
| GRB2 | ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084 | growth factor receptor-bound protein 2 | Grb2 interacts with Cbl. | BIND | 15782196 |
| c-Cbl interacts with Grb2. This interaction was modeled on a demonstrated interaction between human c-Cbl and Grb2 from an unspecified species. | BIND | 11053437 |
Affinity Capture-Western Reconstituted Complex Two-hybrid | BioGRID | 8083187 |9108392 |9174058 |9178909 |9367879 |9461587 |9872323 |10086340 |10204582 |10570290 |11964172 |11997436
|
| - | HPRD | 9108392 |9178909 |11133830 |11964172
|
| HCK | JTK9 | hemopoietic cell kinase | - | HPRD,BioGRID | 10092522 |
| INPPL1 | SHIP2 | inositol polyphosphate phosphatase-like 1 | - | HPRD,BioGRID | 12504111 |
| ITK | EMT | LYK | MGC126257 | MGC126258 | PSCTK2 | IL2-inducible T-cell kinase | - | HPRD,BioGRID | 8810341 |
| KRT18 | CYK18 | K18 | keratin 18 | c-Cbl interacts with Keratin 18. | BIND | 9367879 |
| - | HPRD,BioGRID | 9367879 |
| LCK | YT16 | p56lck | pp58lck | lymphocyte-specific protein tyrosine kinase | - | HPRD,BioGRID | 9178909 |11741956 |11904433 |
| LCP2 | SLP-76 | SLP76 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | - | HPRD,BioGRID | 10204582 |
| LTK | TYK1 | leukocyte receptor tyrosine kinase | - | HPRD,BioGRID | 9223670 |
| LYN | FLJ26625 | JTK8 | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | Affinity Capture-Western | BioGRID | 12244174 |
| - | HPRD | 12149655 |
| MET | AUTS9 | HGFR | RCCP2 | c-Met | met proto-oncogene (hepatocyte growth factor receptor) | Met interacts with Cbl. | BIND | 11894096 |
| - | HPRD,BioGRID | 11894096 |
| MYO1C | FLJ23903 | MMI-beta | MMIb | NMI | myr2 | myosin IC | Two-hybrid | BioGRID | 9367879 |
| NCK1 | MGC12668 | NCK | NCKalpha | NCK adaptor protein 1 | Affinity Capture-Western | BioGRID | 10204582 |11494134
|
| OSTF1 | FLJ20559 | OSF | SH3P2 | bA235O14.1 | osteoclast stimulating factor 1 | Cbl interacts with SH3P2. | BIND | 15135048 |
| PDGFRA | CD140A | MGC74795 | PDGFR2 | Rhe-PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | Affinity Capture-Western Reconstituted Complex | BioGRID | 9234717 |
| PDGFRB | CD140B | JTK12 | PDGF-R-beta | PDGFR | PDGFR1 | platelet-derived growth factor receptor, beta polypeptide | c-Cbl interacts with and ubiquitinates PDGF-R-beta. This interaction was modeled on a demonstrated interaction between human c-Cbl and PDGF-R-beta from an unspecified species. | BIND | 10514377 |
| PIK3CA | MGC142161 | MGC142163 | PI3K | p110-alpha | phosphoinositide-3-kinase, catalytic, alpha polypeptide | Co-purification | BioGRID | 8641358 |
| PIK3R1 | GRB1 | p85 | p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | Affinity Capture-Western | BioGRID | 9461587 |9918857
|
| PIK3R2 | P85B | p85 | p85-BETA | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | - | HPRD,BioGRID | 7629144 |
| PLCG1 | PLC-II | PLC1 | PLC148 | PLCgamma1 | phospholipase C, gamma 1 | - | HPRD,BioGRID | 9712732 |12061819
|
| PTK2B | CADTK | CAKB | FADK2 | FAK2 | FRNK | PKB | PTK | PYK2 | RAFTK | PTK2B protein tyrosine kinase 2 beta | - | HPRD,BioGRID | 11149930 |
| PTPN22 | LYP | Lyp1 | Lyp2 | PEP | PTPN8 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | - | HPRD | 10068674 |
| PTPN6 | HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1 | protein tyrosine phosphatase, non-receptor type 6 | - | HPRD,BioGRID | 12176909 |
| PXN | FLJ16691 | paxillin | Co-purification | BioGRID | 8641358 |
| RET | CDHF12 | HSCR1 | MEN2A | MEN2B | MTC1 | PTC | RET-ELE1 | RET51 | ret proto-oncogene | - | HPRD | 12727845 |
| SH2B2 | APS | SH2B adaptor protein 2 | Reconstituted Complex | BioGRID | 10374881 |
| SH3BP2 | 3BP2 | CRBM | CRPM | FLJ42079 | RES4-23 | SH3-domain binding protein 2 | Reconstituted Complex | BioGRID | 9846481 |
| SH3GL2 | CNSA2 | EEN-B1 | FLJ20276 | FLJ25015 | SH3D2A | SH3P4 | SH3-domain GRB2-like 2 | - | HPRD | 11894096 |
| Affinity Capture-Western | BioGRID | 11894095 |
| SH3GL3 | CNSA3 | EEN-2B-L3 | EEN-B2 | HsT19371 | SH3D2C | SH3P13 | SH3-domain GRB2-like 3 | - | HPRD,BioGRID | 11894096 |
| SH3KBP1 | CIN85 | GIG10 | MIG18 | SH3-domain kinase binding protein 1 | - | HPRD,BioGRID | 11894095 |
| CIN85 interacts with Cbl. | BIND | 11894095 |
| SHC1 | FLJ26504 | SHC | SHCA | SHC (Src homology 2 domain containing) transforming protein 1 | - | HPRD,BioGRID | 10570290 |
| SLA | SLA1 | SLAP | Src-like-adaptor | - | HPRD,BioGRID | 10449770 |
| SLA2 | C20orf156 | FLJ21992 | MGC49845 | SLAP-2 | SLAP2 | Src-like-adaptor 2 | - | HPRD,BioGRID | 11891219 |12024036
|
| SORBS1 | CAP | DKFZp451C066 | DKFZp586P1422 | FLAF2 | FLJ12406 | KIAA1296 | R85FL | SH3D5 | SH3P12 | SORB1 | sorbin and SH3 domain containing 1 | - | HPRD | 11001060 |
| Affinity Capture-Western | BioGRID | 12504111 |15128873
|
| An unspecified isoform of CAP interacts with Cbl. This interaction was modeled on a demonstrated interaction between CAP from an unspecified species and human Cbl. | BIND | 15128873 |
| SORBS2 | ARGBP2 | FLJ93447 | KIAA0777 | PRO0618 | sorbin and SH3 domain containing 2 | Affinity Capture-Western Reconstituted Complex Two-hybrid | BioGRID | 12475393 |15128873
|
| ArgBP2 interacts with Cbl. | BIND | 15128873 |
| ArgBP2-A interacts with Cbl. | BIND | 12475393 |
| SPRY2 | MGC23039 | hSPRY2 | sprouty homolog 2 (Drosophila) | - | HPRD,BioGRID | 11053437 |12234920
|
| c-Cbl interacts with hSpry2. This interaction was modeled on a demonstrated interaction between c-Cbl from an unspecified species and human hSpry2. | BIND | 12234920 |
| SPRY2 interacts with c-Cbl. | BIND | 11053437 |
| hSpry2 interacts with c-Cbl. | BIND | 12815057 |
| SRC | ASV | SRC1 | c-SRC | p60-Src | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | - | HPRD | 8635998 |
| Cbl interacts with Src. This interaction was modeled on a demonstrated interaction between human Cbl and Src from unspecified species. | BIND | 15135048 |
| SYK | DKFZp313N1010 | FLJ25043 | FLJ37489 | spleen tyrosine kinase | Affinity Capture-Western Reconstituted Complex | BioGRID | 9857068 |11331248 |12435267 |
| - | HPRD | 9857068 |10540342 |11133830 |
| TLN1 | ILWEQ | KIAA1027 | TLN | talin 1 | Co-purification | BioGRID | 8641358 |
| TYK2 | JTK1 | tyrosine kinase 2 | Affinity Capture-Western | BioGRID | 8780698 |
| UBASH3B | KIAA1959 | MGC15437 | STS-1 | STS1 | p70 | ubiquitin associated and SH3 domain containing, B | - | HPRD | 15159412 |
| UBE2D2 | E2(17)KB2 | PUBC1 | UBC4 | UBC4/5 | UBCH5B | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | - | HPRD,BioGRID | 10514377 |
| c-Cbl interacts with Ubc4. | BIND | 10514377 |
| UBE2G1 | E217K | UBC7 | UBE2G | ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast) | - | HPRD | 11032556 |
| UBE2G2 | UBC7 | ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast) | - | HPRD | 11032556 |
| UBE2L3 | E2-F1 | L-UBC | UBCH7 | UbcM4 | ubiquitin-conjugating enzyme E2L 3 | Affinity Capture-Western Co-crystal Structure Reconstituted Complex | BioGRID | 10531381 |10966114 |12234920 |
| - | HPRD | 10531381 |10966114 |11278816 |
| c-Cbl interacts with an unspecified isoform of UbcH7. This interaction was modeled on a demonstrated interaction between c-Cbl from an unspecified species and human UbcH7. | BIND | 12234920 |
| VAV1 | VAV | vav 1 guanine nucleotide exchange factor | - | HPRD | 9200440 |11133830
|
Affinity Capture-Western Far Western Reconstituted Complex | BioGRID | 9200440 |11331248
|
| VAV2 | - | vav 2 guanine nucleotide exchange factor | - | HPRD | 11313921 |
| YWHAB | GW128 | HS1 | KCIP-1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | c-Cbl interacts with 14-3-3-beta. | BIND | 9367879 |
Affinity Capture-Western Reconstituted Complex Two-hybrid | BioGRID | 9367879 |
| YWHAQ | 14-3-3 | 1C5 | HS1 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | - | HPRD,BioGRID | 8663231 |11024037
|
| YWHAZ | KCIP-1 | MGC111427 | MGC126532 | MGC138156 | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | Two-hybrid | BioGRID | 9367879 |
| c-Cbl interacts with 14-3-3-zeta. | BIND | 9367879 |
| ZAP70 | FLJ17670 | FLJ17679 | SRK | STD | TZK | ZAP-70 | zeta-chain (TCR) associated protein kinase 70kDa | Affinity Capture-Western Co-crystal Structure | BioGRID | 8798643 |10078535
|