Gene Page: CCKBR

Summary
GeneID  887
Symbol  CCKBR
Synonyms  CCK-B|CCK2R|GASR
Description  cholecystokinin B receptor
See related  HGNC:1571|MIM:118445|Ensembl:ENSG00000110148|HPRD:00323|
Locus tag  -
Gene type  protein-coding
Map location  11p15.4
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
UBA30.910.88
POLR3F0.900.87
MRPS350.900.86
ORC4L0.880.87
DCK0.880.86
PMPCB0.870.84
C11orf460.870.84
ATG50.870.84
FAM49B0.860.83
RG9MTD10.860.85
Top 10 negatively co-expressed genes
AF347015.26-0.67-0.62
AF347015.2-0.65-0.59
MT-CO2-0.65-0.57
AF347015.8-0.65-0.59
MT-CYB-0.64-0.58
AF347015.15-0.63-0.58
AF347015.18-0.62-0.62
AF347015.33-0.62-0.57
AF347015.31-0.60-0.54
GPT-0.59-0.60
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0004872receptor activityIEA-
GO:0004435phosphoinositide phospholipase C activityTAS7681836 
GO:0015054gastrin receptor activityIEA-
GO:00469351-phosphatidylinositol-3-kinase regulator activityTAS10400698 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007202activation of phospholipase C activityTAS7681836 
GO:0007204elevation of cytosolic calcium ion concentrationTAS7681836 
GO:0008284positive regulation of cell proliferationTAS8349705 
GO:0007631feeding behaviorTAS7681836 
GO:0007600sensory perceptionTAS7681836 
GO:0007586digestionTAS7681836 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005886plasma membraneTAS7681836 
GO:0005887integral to plasma membraneTAS7681836 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CCKMGC117187cholecystokininin vitro
in vivo
Reconstituted Complex		BioGRID10438490 |12695525 
|15001692 |15520004 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CALCIUM_SIGNALING_PATHWAY 178134All SZGR genes in this pathway
KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 272195All SZGR genes in this pathway
REACTOME_GASTRIN_CREB_SIGNALLING_PATHWAY_VIA_PKC_AND_MAPK 205136All SZGR genes in this pathway
REACTOME_SIGNALING_BY_GPCR 920449All SZGR genes in this pathway
REACTOME_PEPTIDE_LIGAND_BINDING_RECEPTORS 188108All SZGR genes in this pathway
REACTOME_CLASS_A1_RHODOPSIN_LIKE_RECEPTORS 305177All SZGR genes in this pathway
REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS 184116All SZGR genes in this pathway
REACTOME_GPCR_DOWNSTREAM_SIGNALING 805368All SZGR genes in this pathway
REACTOME_GPCR_LIGAND_BINDING 408246All SZGR genes in this pathway
HAMAI_APOPTOSIS_VIA_TRAIL_DN 186107All SZGR genes in this pathway
KORKOLA_YOLK_SAC_TUMOR 6233All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5 9459All SZGR genes in this pathway
PUJANA_ATM_PCC_NETWORK 1442892All SZGR genes in this pathway
BENPORATH_MYC_TARGETS_WITH_EBOX 230156All SZGR genes in this pathway
ASTON_MAJOR_DEPRESSIVE_DISORDER_UP 4936All SZGR genes in this pathway
FERNANDEZ_BOUND_BY_MYC 182116All SZGR genes in this pathway
LU_AGING_BRAIN_DN 153120All SZGR genes in this pathway
SMID_BREAST_CANCER_BASAL_UP 648398All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K27ME3 7959All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
DANG_MYC_TARGETS_UP 143100All SZGR genes in this pathway
DANG_BOUND_BY_MYC 1103714All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K27ME3 341243All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
GUILLAUMOND_KLF10_TARGETS_UP 5139All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-148/1524234291Ahsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
hsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-30-3p4794861A,m8hsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
hsa-miR-30a-3pCUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3pCUUUCAGUCGGAUGUUUACAGC
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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