Summary ?
GeneID8989
SymbolTRPA1
SynonymsANKTM1|FEPS
Descriptiontransient receptor potential cation channel subfamily A member 1
ReferenceMIM:604775|HGNC:HGNC:497|Ensembl:ENSG00000104321|HPRD:09208|Vega:OTTHUMG00000164516
Gene typeprotein-coding
Map location8q13
Pascal p-value0.375
eGeneMeta

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
DVL30.970.97
EHMT20.970.97
WHSC20.970.97
RBM100.970.97
RBM15B0.960.96
U2AF20.960.96
DCAF150.960.95
AXIN10.960.96
NUP620.960.94
CSNK1E0.960.96
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.77-0.90
AF347015.27-0.76-0.89
C5orf53-0.75-0.78
MT-CO2-0.75-0.89
AF347015.33-0.74-0.86
S100B-0.73-0.82
MT-CYB-0.73-0.86
HLA-F-0.72-0.75
AF347015.8-0.71-0.87
COPZ2-0.71-0.80

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP 408247All SZGR 2.0 genes in this pathway
BENPORATH SUZ12 TARGETS 1038678All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS 1062725All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 8Q12 Q22 AMPLICON 13282All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 2 UP 256159All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229713All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B UP 172109All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718401All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY 1839928All SZGR 2.0 genes in this pathway