Summary ?
GeneID90141
SymbolEFCAB11
SynonymsC14orf143
DescriptionEF-hand calcium binding domain 11
ReferenceHGNC:HGNC:20357|Ensembl:ENSG00000140025|HPRD:16609|Vega:OTTHUMG00000148671
Gene typeprotein-coding
Map location14q32.11
Pascal p-value0.584
Fetal beta-0.604
eGenePutamen basal ganglia
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs73705640EFCAB11901410.07trans
rs1469347chr2126401820EFCAB11901410.2trans
rs2070396chr2130878751EFCAB11901410.2trans
rs71571081490389239EFCAB11ENSG00000140025.111.499E-60.0231882gtex_brain_putamen_basal
rs171264601490389515EFCAB11ENSG00000140025.111.499E-60.0231606gtex_brain_putamen_basal
rs44564381490389665EFCAB11ENSG00000140025.111.499E-60.0231456gtex_brain_putamen_basal
rs22817491490389969EFCAB11ENSG00000140025.111.499E-60.0231152gtex_brain_putamen_basal
rs22817501490389998EFCAB11ENSG00000140025.111.499E-60.0231123gtex_brain_putamen_basal
rs22817511490390114EFCAB11ENSG00000140025.111.499E-60.0231007gtex_brain_putamen_basal
rs22817521490390457EFCAB11ENSG00000140025.111.499E-60.0230664gtex_brain_putamen_basal
rs22817531490390566EFCAB11ENSG00000140025.111.499E-60.0230555gtex_brain_putamen_basal
rs22817541490390631EFCAB11ENSG00000140025.111.499E-60.0230490gtex_brain_putamen_basal
rs121007271490390948EFCAB11ENSG00000140025.111.499E-60.0230173gtex_brain_putamen_basal
rs121012511490390968EFCAB11ENSG00000140025.111.499E-60.0230153gtex_brain_putamen_basal
rs111599401490391072EFCAB11ENSG00000140025.111.499E-60.0230049gtex_brain_putamen_basal
rs559218301490391595EFCAB11ENSG00000140025.111.499E-60.0229526gtex_brain_putamen_basal
rs560342771490391886EFCAB11ENSG00000140025.111.499E-60.0229235gtex_brain_putamen_basal
rs121009471490392259EFCAB11ENSG00000140025.111.547E-60.0228862gtex_brain_putamen_basal
rs121005401490392294EFCAB11ENSG00000140025.111.499E-60.0228827gtex_brain_putamen_basal
rs603455581490392770EFCAB11ENSG00000140025.111.499E-60.0228351gtex_brain_putamen_basal
rs575845741490393192EFCAB11ENSG00000140025.111.499E-60.0227929gtex_brain_putamen_basal
rs80131781490393855EFCAB11ENSG00000140025.111.515E-60.0227266gtex_brain_putamen_basal
rs596641571490393905EFCAB11ENSG00000140025.111.499E-60.0227216gtex_brain_putamen_basal
rs726973521490393910EFCAB11ENSG00000140025.111.499E-60.0227211gtex_brain_putamen_basal
rs24018571490394390EFCAB11ENSG00000140025.111.528E-60.0226731gtex_brain_putamen_basal
rs24018581490394401EFCAB11ENSG00000140025.111.499E-60.0226720gtex_brain_putamen_basal
rs24018591490394419EFCAB11ENSG00000140025.111.499E-60.0226702gtex_brain_putamen_basal
rs42933041490394514EFCAB11ENSG00000140025.111.499E-60.0226607gtex_brain_putamen_basal
rs726973551490394784EFCAB11ENSG00000140025.111.499E-60.0226337gtex_brain_putamen_basal
rs1136148211490395225EFCAB11ENSG00000140025.117.611E-70.0225896gtex_brain_putamen_basal
rs726973581490395594EFCAB11ENSG00000140025.111.499E-60.0225527gtex_brain_putamen_basal
rs118451131490396226EFCAB11ENSG00000140025.111.184E-60.0224895gtex_brain_putamen_basal
rs118453271490396591EFCAB11ENSG00000140025.111.499E-60.0224530gtex_brain_putamen_basal
rs561056031490396815EFCAB11ENSG00000140025.111.499E-60.0224306gtex_brain_putamen_basal
rs556331411490396823EFCAB11ENSG00000140025.111.499E-60.0224298gtex_brain_putamen_basal
rs120501761490397158EFCAB11ENSG00000140025.111.499E-60.0223963gtex_brain_putamen_basal
rs120503881490397347EFCAB11ENSG00000140025.111.476E-60.0223774gtex_brain_putamen_basal
rs120501781490397404EFCAB11ENSG00000140025.111.499E-60.0223717gtex_brain_putamen_basal
rs120501831490397445EFCAB11ENSG00000140025.111.499E-60.0223676gtex_brain_putamen_basal
rs120501791490397481EFCAB11ENSG00000140025.111.499E-60.0223640gtex_brain_putamen_basal
rs592720861490397590EFCAB11ENSG00000140025.111.499E-60.0223531gtex_brain_putamen_basal
rs574659321490397718EFCAB11ENSG00000140025.111.499E-60.0223403gtex_brain_putamen_basal
rs724597411490398364EFCAB11ENSG00000140025.111.499E-60.0222757gtex_brain_putamen_basal
rs87781490398907EFCAB11ENSG00000140025.111.499E-60.0222214gtex_brain_putamen_basal
rs37529661490399058EFCAB11ENSG00000140025.111.499E-60.0222063gtex_brain_putamen_basal
rs726973621490399169EFCAB11ENSG00000140025.111.499E-60.0221952gtex_brain_putamen_basal
rs122321641490417508EFCAB11ENSG00000140025.111.337E-60.023613gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
GINESTIER BREAST CANCER 20Q13 AMPLIFICATION UP 11966All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER BASAL VS LULMINAL 330215All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 16521023All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN 1024594All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS UP 344180All SZGR 2.0 genes in this pathway
GEORGES TARGETS OF MIR192 AND MIR215 893528All SZGR 2.0 genes in this pathway
XU GH1 AUTOCRINE TARGETS UP 268157All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953554All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783442All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728415All SZGR 2.0 genes in this pathway
TAVAZOIE METASTASIS 10868All SZGR 2.0 genes in this pathway
PANGAS TUMOR SUPPRESSION BY SMAD1 AND SMAD5 DN 157106All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784464All SZGR 2.0 genes in this pathway