Gene Page: BRSK2

Summary
GeneID  9024
Symbol  BRSK2
Synonyms  C11orf7|FLJ41362|PEN11B|SAD1|STK29
Description  BR serine/threonine kinase 2
See related  HGNC:11405|MIM:609236|Ensembl:ENSG00000174672|
Locus tag  -
Gene type  protein-coding
Map location  11p15.5
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
MPHOSPH80.890.90
GOLGB10.890.90
ANKRD260.870.89
CDC42BPA0.860.88
KIF21A0.850.87
GOLGA40.850.87
EEA10.840.87
FMR10.840.86
DST0.830.84
KIF3A0.830.85
Top 10 negatively co-expressed genes
ENHO-0.64-0.69
METRN-0.55-0.56
AF347015.21-0.55-0.49
C1orf61-0.55-0.62
AF347015.31-0.54-0.52
HIGD1B-0.54-0.53
VAMP5-0.53-0.54
IFI27-0.53-0.51
CLDN5-0.52-0.56
C1orf54-0.52-0.55
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0000287magnesium ion bindingIDA14976552 
GO:0005524ATP bindingIDA14976552 
GO:0004674protein serine/threonine kinase activityIDA14976552 
GO:0004674protein serine/threonine kinase activityIEA-
GO:0016740transferase activityIEA-
GO:0016301kinase activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0030182neuron differentiationISSneuron (GO term level: 8)-
GO:0006468protein amino acid phosphorylationIDA14976552 
GO:0030010establishment of cell polarityISS-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
PID_LKB1_PATHWAY 4737All SZGR genes in this pathway
DARWICHE_SKIN_TUMOR_PROMOTER_DN 185115All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_LOW_DN 165107All SZGR genes in this pathway
DARWICHE_PAPILLOMA_RISK_HIGH_DN 180110All SZGR genes in this pathway
DARWICHE_SQUAMOUS_CELL_CARCINOMA_DN 181107All SZGR genes in this pathway
MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_DN 164111All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_48HR_DN 504323All SZGR genes in this pathway
CAMPS_COLON_CANCER_COPY_NUMBER_UP 9245All SZGR genes in this pathway
HANN_RESISTANCE_TO_BCL2_INHIBITOR_UP 3624All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2 491319All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_UP 857456All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-223743m8hsa-miR-22brainAAGCUGCCAGUUGAAGAACUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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