Gene Page: NAT8
Summary ?
| GeneID | 9027 |
| Symbol | NAT8 |
| Synonyms | ATase2|CCNAT|CML1|GLA|Hcml1|TSC501|TSC510 |
| Description | N-acetyltransferase 8 (putative) |
| Reference | MIM:606716|HGNC:HGNC:18069|Ensembl:ENSG00000144035|HPRD:08413|Vega:OTTHUMG00000129818 |
| Gene type | protein-coding |
| Map location | 2p13.2 |
| Pascal p-value | 2.709E-4 |
| Sherlock p-value | 0.368 |
| eGene | Cerebellar Hemisphere Cerebellum Cortex |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| CHERP | 0.94 | 0.96 |
| PIAS4 | 0.94 | 0.95 |
| UBTF | 0.93 | 0.94 |
| PHRF1 | 0.93 | 0.95 |
| ZC3H4 | 0.93 | 0.95 |
| ZC3H18 | 0.93 | 0.94 |
| NEURL4 | 0.93 | 0.94 |
| ZNF746 | 0.93 | 0.95 |
| PRR12 | 0.93 | 0.94 |
| ZNF212 | 0.93 | 0.94 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.76 | -0.87 |
| MT-CO2 | -0.74 | -0.86 |
| FXYD1 | -0.72 | -0.82 |
| C5orf53 | -0.72 | -0.76 |
| AF347015.27 | -0.72 | -0.84 |
| AF347015.33 | -0.72 | -0.82 |
| B2M | -0.71 | -0.77 |
| HIGD1B | -0.71 | -0.83 |
| COPZ2 | -0.71 | -0.78 |
| MT-CYB | -0.71 | -0.83 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| FUJIWARA PARK2 HEPATOCYTE PROLIFERATION UP | 10 | 8 | All SZGR 2.0 genes in this pathway |
| FUJIWARA PARK2 IN LIVER CANCER DN | 5 | 5 | All SZGR 2.0 genes in this pathway |
| FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN | 546 | 351 | All SZGR 2.0 genes in this pathway |