Gene Page: CD7

Summary ?
GeneID924
SymbolCD7
SynonymsGP40|LEU-9|TP41|Tp40
DescriptionCD7 molecule
ReferenceMIM:186820|HGNC:HGNC:1695|Ensembl:ENSG00000173762|HPRD:01732|Vega:OTTHUMG00000178662
Gene typeprotein-coding
Map location17q25.2-q25.3
Pascal p-value0.432
Fetal beta0.186
DMG1 (# studies)
eGeneAnterior cingulate cortex BA24

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
DMG:vanEijk_2014Genome-wide DNA methylation analysisThis dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). 1
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg183456351780186080CD73.305E-48.668DMG:vanEijk_2014

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs348430291781071421CD7ENSG00000173762.35.597E-70.01-795943gtex_brain_ba24
rs357980261781071436CD7ENSG00000173762.32.381E-70.01-795958gtex_brain_ba24
rs1406466751781071621CD7ENSG00000173762.33.448E-70.01-796143gtex_brain_ba24
rs357933601781071826CD7ENSG00000173762.31.804E-60.01-796348gtex_brain_ba24
rs775722831781072094CD7ENSG00000173762.34.398E-70.01-796616gtex_brain_ba24
rs771820591781072675CD7ENSG00000173762.32.029E-70.01-797197gtex_brain_ba24
rs711937671781075004CD7ENSG00000173762.38.991E-70.01-799526gtex_brain_ba24
rs129509421781075573CD7ENSG00000173762.32.462E-70.01-800095gtex_brain_ba24
rs99021021781075836CD7ENSG00000173762.33.534E-70.01-800358gtex_brain_ba24
rs97478861781076641CD7ENSG00000173762.38.382E-70.01-801163gtex_brain_ba24
rs350884611781076658CD7ENSG00000173762.31.735E-60.01-801180gtex_brain_ba24
rs129469501781077361CD7ENSG00000173762.33.712E-70.01-801883gtex_brain_ba24
rs96748811781078568CD7ENSG00000173762.32.797E-70.01-803090gtex_brain_ba24
rs93305331781078768CD7ENSG00000173762.31.346E-60.01-803290gtex_brain_ba24
rs97971171781079015CD7ENSG00000173762.37.771E-70.01-803537gtex_brain_ba24
rs129461461781079703CD7ENSG00000173762.31.185E-60.01-804225gtex_brain_ba24
rs93305341781080779CD7ENSG00000173762.31.396E-60.01-805301gtex_brain_ba24

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
FOLR20.810.75
HCK0.790.68
PTPN60.790.70
NCF40.780.72
CD680.770.64
ITGB20.750.70
FCGR2A0.740.63
FERMT30.720.68
CTSC0.720.70
CSF3R0.710.62
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AC005921.3-0.27-0.46
AC010300.1-0.27-0.32
ANP32C-0.26-0.36
EIF5B-0.24-0.41
AC145146.3-0.24-0.27
CLK1-0.23-0.27
SFRS18-0.22-0.36
NEUROD6-0.22-0.16
ANKRD36-0.22-0.35
KLHL1-0.22-0.15

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG HEMATOPOIETIC CELL LINEAGE 8860All SZGR 2.0 genes in this pathway
BIOCARTA DC PATHWAY 2220All SZGR 2.0 genes in this pathway
ST FAS SIGNALING PATHWAY 6554All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382904All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 1 DN 12686All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 2 DN 7746All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 SIGNATURE 3 DN 162116All SZGR 2.0 genes in this pathway
ODONNELL TFRC TARGETS UP 456228All SZGR 2.0 genes in this pathway
ALCALA APOPTOSIS 8860All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 17Q21 Q25 AMPLICON 335181All SZGR 2.0 genes in this pathway
SANSOM APC TARGETS DN 366238All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475313All SZGR 2.0 genes in this pathway
HADDAD T LYMPHOCYTE AND NK PROGENITOR DN 6341All SZGR 2.0 genes in this pathway
TAVOR CEBPA TARGETS UP 4836All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED DN 246180All SZGR 2.0 genes in this pathway
HU GENOTOXIC DAMAGE 24HR 3522All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P2 7955All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 3D UP 210124All SZGR 2.0 genes in this pathway
SMID BREAST CANCER LUMINAL B DN 564326All SZGR 2.0 genes in this pathway
SMID BREAST CANCER NORMAL LIKE UP 476285All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL CARCINOMA VS ADENOMA DN 2418All SZGR 2.0 genes in this pathway
QI PLASMACYTOMA UP 259185All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C D DN 252155All SZGR 2.0 genes in this pathway
VILIMAS NOTCH1 TARGETS UP 5241All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP 13179All SZGR 2.0 genes in this pathway
MARSHALL VIRAL INFECTION RESPONSE DN 2921All SZGR 2.0 genes in this pathway
VALK AML CLUSTER 4 3117All SZGR 2.0 genes in this pathway
VALK AML WITH CEBPA 3727All SZGR 2.0 genes in this pathway
MIKKELSEN MCV6 ICP WITH H3K27ME3 7446All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP 307182All SZGR 2.0 genes in this pathway