Gene Page: NOG

Summary
GeneID  9241
Symbol  NOG
Synonyms  SYM1|SYNS1
Description  noggin
See related  HGNC:7866|MIM:602991|Ensembl:ENSG00000183691|HPRD:04291|
Locus tag  -
Gene type  protein-coding
Map location  17q21-q22
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
SLC6A200.810.56
SLC22A20.750.63
SLC13A40.730.78
SLC5A50.690.77
OGN0.660.69
DSP0.620.56
SERPIND10.610.69
GJB20.600.60
SLC22A60.590.69
OMD0.590.54
Top 10 negatively co-expressed genes
LRRC37A-0.18-0.36
CHMP4A-0.17-0.30
NBR2-0.17-0.20
C11orf51-0.14-0.23
ACP6-0.14-0.06
USF2-0.13-0.31
ZRSR2-0.13-0.36
HES4-0.13-0.23
SLC25A28-0.13-0.17
C14orf80-0.13-0.15
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0019955cytokine bindingIPI8752214 
GO:0042803protein homodimerization activityIDA11562478 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007420brain developmentIEABrain (GO term level: 7)-
GO:0048712negative regulation of astrocyte differentiationISSastrocyte, Glial (GO term level: 12)10780858 
GO:0001657ureteric bud developmentIEA-
GO:0001649osteoblast differentiationISS10780858 
GO:0001837epithelial to mesenchymal transitionISS10780858 
GO:0009953dorsal/ventral pattern formationIDA7666191 
GO:0007605sensory perception of soundIEA-
GO:0007389pattern specification processIEA-
GO:0042060wound healingISS10780858 
GO:0035019somatic stem cell maintenanceIMP17889703 
GO:0042733embryonic digit morphogenesisIMP10080184 
GO:0030514negative regulation of BMP signaling pathwayIEA-
GO:0042474middle ear morphogenesisIMP10080184 
GO:0051216cartilage developmentIEA-
GO:0045596negative regulation of cell differentiationIEA-
GO:0048570notochord morphogenesisIEA-
GO:0048706embryonic skeletal system developmentIMP10080184 
GO:0048646anatomical structure formationIEA-
GO:0060044negative regulation of cardiac muscle cell proliferationISS10780858 
GO:0060173limb developmentIMP10080184 
GO:0060272embryonic skeletal joint morphogenesisIMP16151340 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionEXP17029022 
GO:0005576extracellular regionIEA-
GO:0005615extracellular spaceTAS10080184 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
BMP2BMP2Abone morphogenetic protein 2-HPRD10657699 
BMP4BMP2B | BMP2B1 | MCOPS6 | ZYMEbone morphogenetic protein 4-HPRD10657699 
BMP5MGC34244bone morphogenetic protein 5-HPRD11580864 
BMP7OP-1bone morphogenetic protein 7-HPRD,BioGRID12478285 
NOGSYM1 | SYNS1nogginCo-purificationBioGRID12478285 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_TGF_BETA_SIGNALING_PATHWAY 8664All SZGR genes in this pathway
BIOCARTA_ALK_PATHWAY 3729All SZGR genes in this pathway
PID_BMP_PATHWAY 4231All SZGR genes in this pathway
REACTOME_SIGNALING_BY_BMP 2315All SZGR genes in this pathway
HOOI_ST7_TARGETS_DN 12378All SZGR genes in this pathway
TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP 15791All SZGR genes in this pathway
SENESE_HDAC1_AND_HDAC2_TARGETS_DN 232139All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP 722443All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP 12779All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
NIKOLSKY_BREAST_CANCER_17Q21_Q25_AMPLICON 335181All SZGR genes in this pathway
SHEPARD_CRUSH_AND_BURN_MUTANT_UP 197110All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS 882572All SZGR genes in this pathway
WONG_IFNA2_RESISTANCE_DN 3420All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
YAUCH_HEDGEHOG_SIGNALING_PARACRINE_UP 14985All SZGR genes in this pathway
LEE_NAIVE_T_LYMPHOCYTE 1910All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME2_AND_H3K27ME3 349234All SZGR genes in this pathway
MIKKELSEN_MCV6_HCP_WITH_H3K27ME3 435318All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 210148All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_DN 918550All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
ZWANG_TRANSIENTLY_UP_BY_2ND_EGF_PULSE_ONLY 1725838All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-148/152172178m8hsa-miR-148aUCAGUGCACUACAGAACUUUGU
hsa-miR-152brainUCAGUGCAUGACAGAACUUGGG
hsa-miR-148bUCAGUGCAUCACAGAACUUUGU
miR-1811921981Ahsa-miR-181abrainAACAUUCAACGCUGUCGGUGAGU
hsa-miR-181bSZAACAUUCAUUGCUGUCGGUGGG
hsa-miR-181cbrainAACAUUCAACCUGUCGGUGAGU
hsa-miR-181dbrainAACAUUCAUUGUUGUCGGUGGGUU
miR-200bc/4292472541A,m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-3292042101Ahsa-miR-329brainAACACACCUGGUUAACCUCUUU
miR-369-3p2492561A,m8hsa-miR-369-3pAAUAAUACAUGGUUGAUCUUU
miR-374250256m8hsa-miR-374UUAUAAUACAACCUGAUAAGUG
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.