Gene Page: FANK1
Summary ?
| GeneID | 92565 |
| Symbol | FANK1 |
| Synonyms | HSD13 |
| Description | fibronectin type III and ankyrin repeat domains 1 |
| Reference | MIM:611640|HGNC:HGNC:23527|Ensembl:ENSG00000203780|HPRD:09945|Vega:OTTHUMG00000019241 |
| Gene type | protein-coding |
| Map location | 10q26.2 |
| Pascal p-value | 0.028 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_IIA | Genome scan meta-analysis (All samples) | Psr: 0.03487 |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6659821 | chr1 | 110339827 | FANK1 | 92565 | 0.05 | trans | ||
| rs6713473 | chr2 | 11284414 | FANK1 | 92565 | 0.19 | trans | ||
| rs6413977 | 0 | FANK1 | 92565 | 0.19 | trans | |||
| rs4346320 | chr2 | 142150284 | FANK1 | 92565 | 0.19 | trans | ||
| rs7565413 | chr2 | 142151284 | FANK1 | 92565 | 0.19 | trans | ||
| rs1814902 | chr3 | 43251753 | FANK1 | 92565 | 0 | trans | ||
| rs9681394 | chr3 | 43256230 | FANK1 | 92565 | 2.954E-5 | trans | ||
| rs4683367 | chr3 | 43257826 | FANK1 | 92565 | 0 | trans | ||
| rs7621511 | chr3 | 43279877 | FANK1 | 92565 | 0 | trans | ||
| rs4682682 | chr3 | 43387222 | FANK1 | 92565 | 0.05 | trans | ||
| rs17075597 | chr3 | 43396220 | FANK1 | 92565 | 0.05 | trans | ||
| rs1981925 | chr4 | 34348578 | FANK1 | 92565 | 0.01 | trans | ||
| rs4544747 | chr4 | 179527501 | FANK1 | 92565 | 0.12 | trans | ||
| rs11958604 | chr5 | 171909023 | FANK1 | 92565 | 0.17 | trans | ||
| rs17160028 | chr7 | 31292738 | FANK1 | 92565 | 0.03 | trans | ||
| rs16910520 | chr9 | 124088239 | FANK1 | 92565 | 0.15 | trans | ||
| rs2289069 | chr9 | 124088730 | FANK1 | 92565 | 0.15 | trans | ||
| rs2164298 | 0 | FANK1 | 92565 | 0.15 | trans | |||
| rs3747847 | chr9 | 124111627 | FANK1 | 92565 | 0.15 | trans | ||
| rs6478513 | chr9 | 124238226 | FANK1 | 92565 | 0.16 | trans | ||
| rs2091236 | chr15 | 31180458 | FANK1 | 92565 | 0.06 | trans | ||
| rs4796062 | chr17 | 33550003 | FANK1 | 92565 | 0.17 | trans | ||
| rs236517 | chr17 | 68275174 | FANK1 | 92565 | 0.11 | trans | ||
| rs16962554 | chr19 | 29590544 | FANK1 | 92565 | 0.08 | trans | ||
| rs7268640 | chr20 | 47150267 | FANK1 | 92565 | 0.02 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Cellular component | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005634 | nucleus | IEA | - | |
| GO:0005737 | cytoplasm | IEA | - |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| SENGUPTA NASOPHARYNGEAL CARCINOMA DN | 349 | 157 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| ROVERSI GLIOMA COPY NUMBER DN | 54 | 37 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 | 473 | 224 | All SZGR 2.0 genes in this pathway |
| ACEVEDO METHYLATED IN LIVER CANCER DN | 940 | 425 | All SZGR 2.0 genes in this pathway |
| KOINUMA TARGETS OF SMAD2 OR SMAD3 | 824 | 528 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |