Gene Page: GTF3C3
Summary ?
| GeneID | 9330 |
| Symbol | GTF3C3 |
| Synonyms | TFIIIC102|TFIIICgamma|TFiiiC2-102 |
| Description | general transcription factor IIIC subunit 3 |
| Reference | MIM:604888|HGNC:HGNC:4666|Ensembl:ENSG00000119041|HPRD:11997|Vega:OTTHUMG00000154633 |
| Gene type | protein-coding |
| Map location | 2q33.1 |
| Pascal p-value | 0.021 |
| Support | Ascano FMRP targets |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| LRRC59 | 0.93 | 0.94 |
| SPATS2 | 0.92 | 0.93 |
| STRBP | 0.92 | 0.93 |
| VPS26B | 0.92 | 0.93 |
| GLOD4 | 0.92 | 0.91 |
| SF3A3 | 0.91 | 0.92 |
| MKRN1 | 0.91 | 0.93 |
| PSPC1 | 0.91 | 0.92 |
| DNAJC18 | 0.91 | 0.92 |
| C1orf149 | 0.91 | 0.92 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| MT-CO2 | -0.81 | -0.85 |
| AF347015.31 | -0.80 | -0.85 |
| AF347015.33 | -0.80 | -0.84 |
| FXYD1 | -0.79 | -0.88 |
| MT-CYB | -0.78 | -0.84 |
| AF347015.8 | -0.78 | -0.85 |
| AF347015.2 | -0.77 | -0.83 |
| AF347015.27 | -0.76 | -0.84 |
| AF347015.26 | -0.76 | -0.83 |
| AF347015.15 | -0.76 | -0.84 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER | 23 | 12 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL III TRANSCRIPTION | 33 | 18 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSCRIPTION | 210 | 127 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION | 122 | 80 | All SZGR 2.0 genes in this pathway |
| HOLLMANN APOPTOSIS VIA CD40 DN | 267 | 178 | All SZGR 2.0 genes in this pathway |
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | 1382 | 904 | All SZGR 2.0 genes in this pathway |
| WANG LMO4 TARGETS DN | 352 | 225 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| PATIL LIVER CANCER | 747 | 453 | All SZGR 2.0 genes in this pathway |
| AMUNDSON RESPONSE TO ARSENITE | 217 | 143 | All SZGR 2.0 genes in this pathway |
| WOOD EBV EBNA1 TARGETS UP | 110 | 71 | All SZGR 2.0 genes in this pathway |
| SHEN SMARCA2 TARGETS UP | 424 | 268 | All SZGR 2.0 genes in this pathway |
| BOYAULT LIVER CANCER SUBCLASS G3 UP | 188 | 121 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |
| RAO BOUND BY SALL4 | 227 | 149 | All SZGR 2.0 genes in this pathway |