Gene Page: PEX16

Summary ?
GeneID9409
SymbolPEX16
SynonymsPBD8A|PBD8B
Descriptionperoxisomal biogenesis factor 16
ReferenceMIM:603360|HGNC:HGNC:8857|Ensembl:ENSG00000121680|HPRD:04526|Vega:OTTHUMG00000167005
Gene typeprotein-coding
Map location11p11.2
Pascal p-value4.86E-4
Sherlock p-value0.746

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@DNM table

GeneChromosomePositionRefAltTranscriptAA changeMutation typeSiftCG46TraitStudy
PEX16chr1145935423GTNM_004813
NM_057174		.
.		silent
silent		SchizophreniaDNM:Fromer_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
COX7A20.910.82
C6orf1250.900.81
PTCD10.890.79
MRPL520.890.76
TIMM8B0.890.79
NDUFB10.880.78
UQCRQ0.870.74
UBL50.870.81
RP11-844E22.10.850.75
NDUFB70.850.68
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
MYH9-0.51-0.52
MMRN2-0.48-0.54
WNK1-0.47-0.56
ECE1-0.46-0.44
PHLPP1-0.46-0.50
VWF-0.45-0.53
SLC6A6-0.45-0.46
ARHGEF10-0.44-0.49
PODXL-0.44-0.39
TENC1-0.44-0.60

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG PEROXISOME 7847All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER DN 406230All SZGR 2.0 genes in this pathway
DARWICHE SKIN TUMOR PROMOTER DN 185115All SZGR 2.0 genes in this pathway
DARWICHE PAPILLOMA RISK LOW DN 165107All SZGR 2.0 genes in this pathway
DARWICHE PAPILLOMA RISK HIGH DN 180110All SZGR 2.0 genes in this pathway
DARWICHE SQUAMOUS CELL CARCINOMA DN 181107All SZGR 2.0 genes in this pathway
ROVERSI GLIOMA COPY NUMBER UP 10075All SZGR 2.0 genes in this pathway
BENPORATH MYC MAX TARGETS 775494All SZGR 2.0 genes in this pathway
MCDOWELL ACUTE LUNG INJURY DN 4833All SZGR 2.0 genes in this pathway
DOUGLAS BMI1 TARGETS DN 314188All SZGR 2.0 genes in this pathway
IWANAGA CARCINOGENESIS BY KRAS PTEN DN 353226All SZGR 2.0 genes in this pathway
DANG BOUND BY MYC 1103714All SZGR 2.0 genes in this pathway
LU EZH2 TARGETS UP 295155All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 4 UP 11264All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D 882506All SZGR 2.0 genes in this pathway