Summary ?
GeneID94233
SymbolOPN4
SynonymsMOP
Descriptionopsin 4
ReferenceMIM:606665|HGNC:HGNC:14449|Ensembl:ENSG00000122375|HPRD:05977|Vega:OTTHUMG00000018654
Gene typeprotein-coding
Map location10q22
Pascal p-value0.008
eGeneAnterior cingulate cortex BA24
Caudate basal ganglia
Cortex
Frontal Cortex BA9
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs10994209chr1061877705OPN4942330.03trans
rs112020881088357967OPN4ENSG00000122375.73.965E-60.05-56347gtex_brain_ba24
rs112020881088357967OPN4ENSG00000122375.73.155E-80-56347gtex_brain_putamen_basal
rs70687941088359713OPN4ENSG00000122375.75.039E-80-54601gtex_brain_putamen_basal
rs70987121088370239OPN4ENSG00000122375.74.925E-80-44075gtex_brain_putamen_basal
rs112020941088372163OPN4ENSG00000122375.73.077E-80-42151gtex_brain_putamen_basal
rs781836551088372884OPN4ENSG00000122375.72.599E-80-41430gtex_brain_putamen_basal
rs78956671088373279OPN4ENSG00000122375.72.377E-80-41035gtex_brain_putamen_basal
rs123598131088373843OPN4ENSG00000122375.72.089E-80-40471gtex_brain_putamen_basal
rs108876271088378754OPN4ENSG00000122375.77.56E-90-35560gtex_brain_putamen_basal
rs97314591088379834OPN4ENSG00000122375.76.145E-90-34480gtex_brain_putamen_basal
rs1127983301088381693OPN4ENSG00000122375.74.364E-90-32621gtex_brain_putamen_basal
rs70866061088381941OPN4ENSG00000122375.74.181E-90-32373gtex_brain_putamen_basal
rs70712121088381951OPN4ENSG00000122375.74.169E-90-32363gtex_brain_putamen_basal
rs70713151088381960OPN4ENSG00000122375.74.169E-90-32354gtex_brain_putamen_basal
rs79083211088383716OPN4ENSG00000122375.73.085E-90-30598gtex_brain_putamen_basal
rs79178721088386179OPN4ENSG00000122375.71.944E-90-28135gtex_brain_putamen_basal
rs108876301088387574OPN4ENSG00000122375.71.944E-90-26740gtex_brain_putamen_basal
rs70797201088390237OPN4ENSG00000122375.71.944E-90-24077gtex_brain_putamen_basal
rs79005641088392181OPN4ENSG00000122375.73.069E-70-22133gtex_brain_putamen_basal
rs112021011088392435OPN4ENSG00000122375.71.944E-90-21879gtex_brain_putamen_basal
rs610512861088400731OPN4ENSG00000122375.71.944E-90-13583gtex_brain_putamen_basal
rs171068981088401040OPN4ENSG00000122375.71.944E-90-13274gtex_brain_putamen_basal
rs788810731088404726OPN4ENSG00000122375.71.944E-90-9588gtex_brain_putamen_basal
rs28035461088407055OPN4ENSG00000122375.72.61E-60-7259gtex_brain_putamen_basal
rs70895821088407326OPN4ENSG00000122375.71.314E-110-6988gtex_brain_putamen_basal
rs108876371088410462OPN4ENSG00000122375.71.944E-90-3852gtex_brain_putamen_basal
rs20075991088413707OPN4ENSG00000122375.75.469E-70-607gtex_brain_putamen_basal
rs2003721001088414009OPN4ENSG00000122375.77.578E-70-305gtex_brain_putamen_basal
rs344390281088414011OPN4ENSG00000122375.75.469E-70-303gtex_brain_putamen_basal
rs112021051088414255OPN4ENSG00000122375.71.314E-110-59gtex_brain_putamen_basal
rs37403321088418535OPN4ENSG00000122375.71.332E-1104221gtex_brain_putamen_basal
rs37403341088419012OPN4ENSG00000122375.71.314E-1104698gtex_brain_putamen_basal
rs37403351088419641OPN4ENSG00000122375.71.314E-1105327gtex_brain_putamen_basal
rs112021111088424506OPN4ENSG00000122375.71.327E-11010192gtex_brain_putamen_basal
rs37403411088426042OPN4ENSG00000122375.72.666E-11011728gtex_brain_putamen_basal
rs3978972061088426614OPN4ENSG00000122375.71.875E-11012300gtex_brain_putamen_basal
rs118126011088428167OPN4ENSG00000122375.73.36E-7013853gtex_brain_putamen_basal
rs37403421088428718OPN4ENSG00000122375.72.926E-10014404gtex_brain_putamen_basal
rs710161471088428793OPN4ENSG00000122375.72.713E-6014479gtex_brain_putamen_basal
rs108876391088429154OPN4ENSG00000122375.73.954E-10014840gtex_brain_putamen_basal
rs108876401088429356OPN4ENSG00000122375.74.089E-10015042gtex_brain_putamen_basal
rs112021171088431526OPN4ENSG00000122375.76.157E-7017212gtex_brain_putamen_basal
rs112021181088431782OPN4ENSG00000122375.71.168E-7017468gtex_brain_putamen_basal
rs112021191088431823OPN4ENSG00000122375.73.642E-7017509gtex_brain_putamen_basal
rs346772081088431848OPN4ENSG00000122375.73.444E-7017534gtex_brain_putamen_basal
rs112021211088432328OPN4ENSG00000122375.73.444E-7018014gtex_brain_putamen_basal
rs674317741088432491OPN4ENSG00000122375.72.072E-7018177gtex_brain_putamen_basal
rs23543621088432697OPN4ENSG00000122375.73.444E-7018383gtex_brain_putamen_basal
rs23543611088432698OPN4ENSG00000122375.73.444E-7018384gtex_brain_putamen_basal
rs23543601088432743OPN4ENSG00000122375.73.503E-7018429gtex_brain_putamen_basal
rs23543591088432875OPN4ENSG00000122375.73.444E-7018561gtex_brain_putamen_basal
rs78951781088433146OPN4ENSG00000122375.73.444E-7018832gtex_brain_putamen_basal
rs78943811088433203OPN4ENSG00000122375.72.067E-7018889gtex_brain_putamen_basal
rs127718571088434059OPN4ENSG00000122375.72.072E-7019745gtex_brain_putamen_basal
rs115921931088434284OPN4ENSG00000122375.72.072E-7019970gtex_brain_putamen_basal
rs74753111088434380OPN4ENSG00000122375.74.48E-10020066gtex_brain_putamen_basal
rs108876431088435215OPN4ENSG00000122375.72.065E-7020901gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK 205136All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY GPCR 920449All SZGR 2.0 genes in this pathway
REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS 305177All SZGR 2.0 genes in this pathway
REACTOME G ALPHA Q SIGNALLING EVENTS 184116All SZGR 2.0 genes in this pathway
REACTOME GPCR DOWNSTREAM SIGNALING 805368All SZGR 2.0 genes in this pathway
REACTOME GPCR LIGAND BINDING 408246All SZGR 2.0 genes in this pathway
MANTOVANI NFKB TARGETS UP 4333All SZGR 2.0 genes in this pathway
MANTOVANI VIRAL GPCR SIGNALING UP 8654All SZGR 2.0 genes in this pathway
MARTENS TRETINOIN RESPONSE UP 857456All SZGR 2.0 genes in this pathway