Gene Page: CD36

Summary ?
GeneID948
SymbolCD36
SynonymsBDPLT10|CHDS7|FAT|GP3B|GP4|GPIV|PASIV|SCARB3
DescriptionCD36 molecule
ReferenceMIM:173510|HGNC:HGNC:1663|Ensembl:ENSG00000135218|HPRD:01430|Vega:OTTHUMG00000155383
Gene typeprotein-coding
Map location7q11.2
Pascal p-value0.157
Fetal beta0.572

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS
PMID:cooccurHigh-throughput literature-searchSystematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: schizophrenia,schizophreniasClick to show details

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
CD40.720.74
SLC40A10.700.63
IL13RA10.680.71
FZD60.680.67
IRF80.680.60
NCKAP1L0.670.62
ANO60.670.64
ITGA60.660.67
LAPTM50.660.63
PLOD20.660.66
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ZNF814-0.38-0.41
AC132872.1-0.38-0.41
SNHG12-0.34-0.36
AL022328.1-0.33-0.36
EXD3-0.33-0.29
SLC7A9-0.33-0.33
ATAD3B-0.33-0.29
AC011511.1-0.33-0.28
AC040934.2-0.32-0.30
AC092143.1-0.32-0.34

Section IV. Protein-protein interaction annotation

InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CD95H9 | BA2 | BTCC-1 | DRAP-27 | GIG2 | MIC3 | MRP-1 | P24 | TSPAN29CD9 molecule-HPRD,BioGRID11238109 
COL1A1OI4collagen, type I, alpha 1-HPRD,BioGRID2468670 
COL1A2OI4collagen, type I, alpha 2-HPRD,BioGRID10772928 
FYNMGC45350 | SLK | SYNFYN oncogene related to SRC, FGR, YES-HPRD,BioGRID7521304 
HSD11B111-DH | 11-beta-HSD1 | HDL | HSD11 | HSD11B | HSD11L | MGC13539hydroxysteroid (11-beta) dehydrogenase 1Reconstituted ComplexBioGRID9555943 
ITGA2BCD41 | CD41B | GP2B | GPIIb | GTA | HPA3integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)Affinity Capture-WesternBioGRID11238109 
ITGA6CD49f | DKFZp686J01244 | FLJ18737 | ITGA6B | VLA-6integrin, alpha 6Affinity Capture-WesternBioGRID11238109 
ITGB1CD29 | FNRB | GPIIA | MDF2 | MSK12 | VLA-BETA | VLABintegrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)Affinity Capture-WesternBioGRID11238109 
ITGB3CD61 | GP3A | GPIIIaintegrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)Affinity Capture-WesternBioGRID11238109 
LDLRFH | FHClow density lipoprotein receptorReconstituted ComplexBioGRID9555943 
LYNFLJ26625 | JTK8v-yes-1 Yamaguchi sarcoma viral related oncogene homolog-HPRD,BioGRID1715582 
MATKCHK | CTK | DKFZp434N1212 | HHYLTK | HYL | HYLTK | Lsk | MGC1708 | MGC2101megakaryocyte-associated tyrosine kinase-HPRD,BioGRID9171348 
SRCASV | SRC1 | c-SRC | p60-Srcv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)-HPRD7521304 
THBS1THBS | TSP | TSP1thrombospondin 1-HPRD10487979 |10772961 
VLDLRCHRMQ1 | FLJ35024 | VLDLRCHvery low density lipoprotein receptorReconstituted ComplexBioGRID9555943 
YES1HsT441 | P61-YES | Yes | c-yesv-yes-1 Yamaguchi sarcoma viral oncogene homolog 1-HPRD7521304 
YES1HsT441 | P61-YES | Yes | c-yesv-yes-1 Yamaguchi sarcoma viral oncogene homolog 1Affinity Capture-WesternBioGRID1715582 


Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KEGG PPAR SIGNALING PATHWAY 6947All SZGR 2.0 genes in this pathway
KEGG ECM RECEPTOR INTERACTION 8453All SZGR 2.0 genes in this pathway
KEGG HEMATOPOIETIC CELL LINEAGE 8860All SZGR 2.0 genes in this pathway
KEGG ADIPOCYTOKINE SIGNALING PATHWAY 6757All SZGR 2.0 genes in this pathway
BIOCARTA PPARA PATHWAY 5843All SZGR 2.0 genes in this pathway
REACTOME DEVELOPMENTAL BIOLOGY 396292All SZGR 2.0 genes in this pathway
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION 7648All SZGR 2.0 genes in this pathway
REACTOME PPARA ACTIVATES GENE EXPRESSION 10472All SZGR 2.0 genes in this pathway
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 8956All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS 478302All SZGR 2.0 genes in this pathway
REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM 168115All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION 7253All SZGR 2.0 genes in this pathway
REACTOME HEMOSTASIS 466331All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM 933616All SZGR 2.0 genes in this pathway
REACTOME ADAPTIVE IMMUNE SYSTEM 539350All SZGR 2.0 genes in this pathway
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION 251156All SZGR 2.0 genes in this pathway
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION 208138All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL UP 9459All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN 463290All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE DN 244147All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382904All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367220All SZGR 2.0 genes in this pathway
TONKS TARGETS OF RUNX1 RUNX1T1 FUSION HSC DN 187115All SZGR 2.0 genes in this pathway
SABATES COLORECTAL ADENOMA DN 291176All SZGR 2.0 genes in this pathway
JAATINEN HEMATOPOIETIC STEM CELL DN 226132All SZGR 2.0 genes in this pathway
GRAHAM CML QUIESCENT VS NORMAL QUIESCENT UP 8745All SZGR 2.0 genes in this pathway
GRAHAM CML DIVIDING VS NORMAL QUIESCENT UP 181101All SZGR 2.0 genes in this pathway
GRAHAM NORMAL QUIESCENT VS NORMAL DIVIDING DN 8749All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP 293179All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN 232154All SZGR 2.0 genes in this pathway
LANDIS ERBB2 BREAST PRENEOPLASTIC DN 5533All SZGR 2.0 genes in this pathway
LANDIS ERBB2 BREAST TUMORS 324 DN 14993All SZGR 2.0 genes in this pathway
EBAUER TARGETS OF PAX3 FOXO1 FUSION UP 207128All SZGR 2.0 genes in this pathway
MOHANKUMAR TLX1 TARGETS UP 414287All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442892All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN 382224All SZGR 2.0 genes in this pathway
MORI SMALL PRE BII LYMPHOCYTE DN 7652All SZGR 2.0 genes in this pathway
LEE LIVER CANCER CIPROFIBRATE UP 6042All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882572All SZGR 2.0 genes in this pathway
DORSAM HOXA9 TARGETS DN 3222All SZGR 2.0 genes in this pathway
SCHURINGA STAT5A TARGETS UP 2113All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475313All SZGR 2.0 genes in this pathway
ABRAHAM ALPC VS MULTIPLE MYELOMA UP 2622All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED UP 183111All SZGR 2.0 genes in this pathway
KANG IMMORTALIZED BY TERT UP 8961All SZGR 2.0 genes in this pathway
JAZAERI BREAST CANCER BRCA1 VS BRCA2 DN 4331All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830547All SZGR 2.0 genes in this pathway
CHIBA RESPONSE TO TSA UP 5233All SZGR 2.0 genes in this pathway
CHEN ETV5 TARGETS SERTOLI 2010All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE DN 261183All SZGR 2.0 genes in this pathway
ZAMORA NOS2 TARGETS DN 9671All SZGR 2.0 genes in this pathway
WENG POR TARGETS LIVER UP 4129All SZGR 2.0 genes in this pathway
GERHOLD ADIPOGENESIS UP 4940All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY 4NQO 3824All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE DN 195135All SZGR 2.0 genes in this pathway
ZHANG GATA6 TARGETS UP 1512All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS UP 673430All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS DN 543317All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS UP 602364All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS UP 601369All SZGR 2.0 genes in this pathway
MASSARWEH TAMOXIFEN RESISTANCE UP 578341All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP 430288All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701446All SZGR 2.0 genes in this pathway
ZHENG GLIOBLASTOMA PLASTICITY UP 250168All SZGR 2.0 genes in this pathway
GRADE COLON CANCER DN 3322All SZGR 2.0 genes in this pathway
RAY TUMORIGENESIS BY ERBB2 CDC25A UP 10457All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS UP 9356All SZGR 2.0 genes in this pathway
VART KSHV INFECTION ANGIOGENIC MARKERS DN 13892All SZGR 2.0 genes in this pathway
HOFFMANN SMALL PRE BII TO IMMATURE B LYMPHOCYTE UP 7049All SZGR 2.0 genes in this pathway
HOFFMANN IMMATURE TO MATURE B LYMPHOCYTE DN 5036All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210725All SZGR 2.0 genes in this pathway
LIU VAV3 PROSTATE CARCINOGENESIS UP 8961All SZGR 2.0 genes in this pathway
ROME INSULIN TARGETS IN MUSCLE UP 442263All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 UP 176110All SZGR 2.0 genes in this pathway
NAKAYAMA SOFT TISSUE TUMORS PCA2 DN 8051All SZGR 2.0 genes in this pathway
NAKAMURA ADIPOGENESIS LATE UP 10467All SZGR 2.0 genes in this pathway
HOFFMAN CLOCK TARGETS UP 117All SZGR 2.0 genes in this pathway
WANG RESPONSE TO GSK3 INHIBITOR SB216763 UP 397206All SZGR 2.0 genes in this pathway
WANG CLASSIC ADIPOGENIC TARGETS OF PPARG 2615All SZGR 2.0 genes in this pathway
OHGUCHI LIVER HNF4A TARGETS UP 4430All SZGR 2.0 genes in this pathway
STEGER ADIPOGENESIS UP 2116All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682433All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D 882506All SZGR 2.0 genes in this pathway
PLASARI TGFB1 TARGETS 10HR DN 244157All SZGR 2.0 genes in this pathway
SANDERSON PPARA TARGETS 157All SZGR 2.0 genes in this pathway
GUILLAUMOND KLF10 TARGETS DN 3015All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL UP 489314All SZGR 2.0 genes in this pathway