Gene Page: BAG4
Summary ?
| GeneID | 9530 |
| Symbol | BAG4 |
| Synonyms | BAG-4|SODD |
| Description | BCL2 associated athanogene 4 |
| Reference | MIM:603884|HGNC:HGNC:940|Ensembl:ENSG00000156735|HPRD:04861|Vega:OTTHUMG00000164064 |
| Gene type | protein-coding |
| Map location | 8p11.23 |
| Pascal p-value | 9.952E-6 |
| eGene | Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10915848 | chr1 | 225788919 | BAG4 | 9530 | 0.14 | trans | ||
| rs1155107 | chr3 | 26843376 | BAG4 | 9530 | 0.16 | trans | ||
| rs17029291 | chr3 | 32402138 | BAG4 | 9530 | 0 | trans | ||
| rs1553189 | chr3 | 112939422 | BAG4 | 9530 | 0.17 | trans | ||
| rs829501 | chr3 | 165500234 | BAG4 | 9530 | 0.11 | trans | ||
| rs4680661 | chr3 | 165505524 | BAG4 | 9530 | 0.13 | trans | ||
| rs6771817 | chr3 | 165557099 | BAG4 | 9530 | 0.06 | trans | ||
| rs9881386 | chr3 | 165594832 | BAG4 | 9530 | 0.11 | trans | ||
| rs830202 | chr3 | 165654796 | BAG4 | 9530 | 9.474E-4 | trans | ||
| rs282224 | chr3 | 165671505 | BAG4 | 9530 | 0.05 | trans | ||
| rs4645225 | chr4 | 126010830 | BAG4 | 9530 | 0.16 | trans | ||
| rs2008349 | chr4 | 142819748 | BAG4 | 9530 | 0.16 | trans | ||
| rs17146240 | chr5 | 119522933 | BAG4 | 9530 | 0.04 | trans | ||
| rs17146261 | chr5 | 119534252 | BAG4 | 9530 | 0.04 | trans | ||
| rs1432030 | chr8 | 133175445 | BAG4 | 9530 | 0.1 | trans | ||
| rs7894597 | chr10 | 9384581 | BAG4 | 9530 | 0.01 | trans | ||
| rs12253630 | chr10 | 74768923 | BAG4 | 9530 | 0.04 | trans | ||
| rs7078127 | chr10 | 74847633 | BAG4 | 9530 | 0.01 | trans | ||
| rs3829166 | chr10 | 74879373 | BAG4 | 9530 | 0.06 | trans | ||
| rs12569493 | chr10 | 74886042 | BAG4 | 9530 | 0.01 | trans | ||
| rs7072086 | chr10 | 74886597 | BAG4 | 9530 | 0.06 | trans | ||
| rs16930362 | chr10 | 74890320 | BAG4 | 9530 | 8.943E-4 | trans | ||
| rs7083730 | chr10 | 74890448 | BAG4 | 9530 | 0.16 | trans | ||
| rs2271904 | chr10 | 74894374 | BAG4 | 9530 | 0.01 | trans | ||
| rs7092445 | chr10 | 74921991 | BAG4 | 9530 | 0 | trans | ||
| rs12256576 | chr10 | 74934313 | BAG4 | 9530 | 0.02 | trans | ||
| rs1867565 | chr10 | 74977780 | BAG4 | 9530 | 0.02 | trans | ||
| rs11000557 | chr10 | 74987393 | BAG4 | 9530 | 0.03 | trans | ||
| rs16915029 | chr10 | 75001994 | BAG4 | 9530 | 0.01 | trans | ||
| rs14488 | chr10 | 75007274 | BAG4 | 9530 | 0.05 | trans | ||
| rs16930466 | chr10 | 75007587 | BAG4 | 9530 | 0.06 | trans | ||
| rs11000607 | chr10 | 75089777 | BAG4 | 9530 | 0.01 | trans | ||
| rs6480700 | chr10 | 75101689 | BAG4 | 9530 | 0.05 | trans | ||
| rs12571454 | chr10 | 75208954 | BAG4 | 9530 | 0.01 | trans | ||
| rs1324669 | chr13 | 107872446 | BAG4 | 9530 | 8.74E-4 | trans | ||
| rs16958358 | chr17 | 55502410 | BAG4 | 9530 | 0.03 | trans | ||
| rs6098023 | chr20 | 53113740 | BAG4 | 9530 | 0.01 | trans | ||
| rs6015314 | chr20 | 57167224 | BAG4 | 9530 | 0.01 | trans | ||
| rs17145698 | chrX | 40218345 | BAG4 | 9530 | 0.01 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| BIOCARTA HIVNEF PATHWAY | 58 | 43 | All SZGR 2.0 genes in this pathway |
| BIOCARTA SODD PATHWAY | 10 | 7 | All SZGR 2.0 genes in this pathway |
| BIOCARTA TNFR1 PATHWAY | 29 | 21 | All SZGR 2.0 genes in this pathway |
| ST TUMOR NECROSIS FACTOR PATHWAY | 29 | 20 | All SZGR 2.0 genes in this pathway |
| PID TNF PATHWAY | 46 | 33 | All SZGR 2.0 genes in this pathway |
| PID CERAMIDE PATHWAY | 48 | 37 | All SZGR 2.0 genes in this pathway |
| PID HIV NEF PATHWAY | 35 | 26 | All SZGR 2.0 genes in this pathway |
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | 1382 | 904 | All SZGR 2.0 genes in this pathway |
| SNIJDERS AMPLIFIED IN HEAD AND NECK TUMORS | 37 | 27 | All SZGR 2.0 genes in this pathway |
| SHETH LIVER CANCER VS TXNIP LOSS PAM4 | 261 | 153 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS UP | 1037 | 673 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 8P12 P11 AMPLICON | 57 | 32 | All SZGR 2.0 genes in this pathway |
| DING LUNG CANCER EXPRESSION BY COPY NUMBER | 100 | 62 | All SZGR 2.0 genes in this pathway |
| KYNG RESPONSE TO H2O2 | 71 | 42 | All SZGR 2.0 genes in this pathway |
| DOUGLAS BMI1 TARGETS UP | 566 | 371 | All SZGR 2.0 genes in this pathway |
| MARTINEZ RB1 TARGETS DN | 543 | 317 | All SZGR 2.0 genes in this pathway |
| MARTINEZ TP53 TARGETS UP | 602 | 364 | All SZGR 2.0 genes in this pathway |
| MARTINEZ RB1 AND TP53 TARGETS UP | 601 | 369 | All SZGR 2.0 genes in this pathway |
| RIZKI TUMOR INVASIVENESS 3D DN | 270 | 181 | All SZGR 2.0 genes in this pathway |
| AGUIRRE PANCREATIC CANCER COPY NUMBER UP | 298 | 174 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |