Gene Page: FEZ1

Summary
GeneID  9638
Symbol  FEZ1
Synonyms  -
Description  fasciculation and elongation protein zeta 1 (zygin I)
See related  HGNC:3659|MIM:604825|Ensembl:ENSG00000149557|HPRD:09212|
Locus tag  -
Gene type  protein-coding
Map location  11q24.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 2 
NetworkShortest path distance of core genes in the Human protein-protein interaction networkContribution to shortest path in PPI network: 31 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
COIL0.970.97
CAND10.970.97
KLHL70.970.97
XRCC50.970.97
POLR2B0.970.97
ACTR30.970.97
MARCH70.970.97
ABCE10.960.96
CDC5L0.960.97
CCT6A0.960.96
Top 10 negatively co-expressed genes
MT-CO2-0.73-0.90
FXYD1-0.73-0.90
AF347015.31-0.73-0.89
AF347015.33-0.72-0.88
HLA-F-0.71-0.81
AF347015.27-0.71-0.87
MT-CYB-0.71-0.87
AIFM3-0.70-0.80
AF347015.8-0.70-0.88
IFI27-0.70-0.86
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIPI14690447 |15383276 |16169070 
GO:0043015gamma-tubulin bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007411axon guidanceTASaxon (GO term level: 13)9096408 
GO:0007399nervous system developmentTASneurite (GO term level: 5)9096408 
GO:0007155cell adhesionTAS9096408 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005813centrosomeIEA-
GO:0005737cytoplasmIEA-
GO:0005886plasma membraneIEA-
 
Protein-protein InteractionsShown by network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
ACTG1ACT | ACTG | DFNA20 | DFNA26actin, gamma 1Affinity Capture-WesternBioGRID12874605 
C13orf34BORA | FLJ22624chromosome 13 open reading frame 34Two-hybridBioGRID16169070 
CCL7FIC | MARC | MCP-3 | MCP3 | MGC138463 | MGC138465 | NC28 | SCYA6 | SCYA7chemokine (C-C motif) ligand 7Two-hybridBioGRID16169070 
CIB1CIB | KIP | KIP1 | SIP2-28calcium and integrin binding 1 (calmyrin)-HPRD11856312 
COL9A2DJ39G22.4 | EDM2 | MEDcollagen, type IX, alpha 2Two-hybridBioGRID16169070 
CSTF2CstF-64cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDaTwo-hybridBioGRID16169070 
DIS3L2FAM6A | FLJ36974 | MGC42174DIS3 mitotic control homolog (S. cerevisiae)-like 2Two-hybridBioGRID16169070 
DISC1C1orf136 | FLJ13381 | FLJ21640 | FLJ25311 | FLJ41105 | KIAA0457 | SCZD9disrupted in schizophrenia 1-HPRD,BioGRID12874605 
GTF2F1BTF4 | RAP74 | TF2F1 | TFIIFgeneral transcription factor IIF, polypeptide 1, 74kDaTwo-hybridBioGRID16169070 
HEATR2FLJ20397 | FLJ25564 | FLJ31671 | FLJ39381HEAT repeat containing 2Two-hybridBioGRID16169070 
HTATSF1TAT-SF1 | dJ196E23.2HIV-1 Tat specific factor 1Two-hybridBioGRID16169070 
MagmasCGI-136mitochondria-associated protein involved in granulocyte-macrophage colony-stimulating factor signal transductionTwo-hybridBioGRID16169070 
NBR11A1-3B | KIAA0049 | M17S2 | MIG19neighbor of BRCA1 gene 1-HPRD,BioGRID11856312 
NDUFB9B22 | DKFZp566O173 | FLJ22885 | LYRM3 | UQOR22NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDaTwo-hybridBioGRID16169070 
NEK1DKFZp686D06121 | DKFZp686K12169 | KIAA1901 | MGC138800 | NY-REN-55NIMA (never in mitosis gene a)-related kinase 1NEK1 interacts with FEZ-1.BIND14690447 
OLFML3HNOEL-iso | OLF44olfactomedin-like 3Two-hybridBioGRID16169070 
P4HBDSI | ERBA2L | GIT | PDI | PDIA1 | PHDB | PO4DB | PO4HB | PROHBprocollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptideTwo-hybridBioGRID16169070 
PDCD7ES18 | HES18 | MGC22015programmed cell death 7Two-hybridBioGRID16169070 
PRKCZPKC-ZETA | PKC2protein kinase C, zeta-HPRD,BioGRID9971736 
PTHPTH1parathyroid hormoneTwo-hybridBioGRID16169070 
PTPRSPTPSIGMAprotein tyrosine phosphatase, receptor type, STwo-hybridBioGRID16169070 
SMEK2FLFL2 | FLJ31474 | KIAA1387 | PP4R3B | PSY2 | smk1SMEK homolog 2, suppressor of mek1 (Dictyostelium)Two-hybridBioGRID16169070 
STARSTARD1steroidogenic acute regulatory proteinTwo-hybridBioGRID16169070 
TAC3NKB | NKNB | PRO1155 | ZNEUROK1tachykinin 3Two-hybridBioGRID16169070 
TOMM20KIAA0016 | MAS20 | MGC117367 | MOM19 | TOM20translocase of outer mitochondrial membrane 20 homolog (yeast)Two-hybridBioGRID16169070 
TTRHsT2651 | PALB | TBPAtransthyretinTwo-hybridBioGRID16169070 
TXNDC9APACDthioredoxin domain containing 9Two-hybridBioGRID16169070 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
LIU_PROSTATE_CANCER_DN 481290All SZGR genes in this pathway
LIU_SOX4_TARGETS_UP 13794All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP 14686All SZGR genes in this pathway
MULLIGHAN_MLL_SIGNATURE_2_UP 418263All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP 177113All SZGR genes in this pathway
ENK_UV_RESPONSE_KERATINOCYTE_DN 485334All SZGR genes in this pathway
DELYS_THYROID_CANCER_DN 232154All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP 612367All SZGR genes in this pathway
GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP 185119All SZGR genes in this pathway
SHIRAISHI_PLZF_TARGETS_UP 105All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
DIRMEIER_LMP1_RESPONSE_LATE_UP 5741All SZGR genes in this pathway
SCHLESINGER_METHYLATED_DE_NOVO_IN_CANCER 8864All SZGR genes in this pathway
BENPORATH_NANOG_TARGETS 988594All SZGR genes in this pathway
BENPORATH_OCT4_TARGETS 290172All SZGR genes in this pathway
BENPORATH_SOX2_TARGETS 734436All SZGR genes in this pathway
BENPORATH_NOS_TARGETS 179105All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
BENPORATH_ES_WITH_H3K27ME3 1118744All SZGR genes in this pathway
BENPORATH_PRC2_TARGETS 652441All SZGR genes in this pathway
ONDER_CDH1_TARGETS_2_DN 464276All SZGR genes in this pathway
ROZANOV_MMP14_TARGETS_UP 266171All SZGR genes in this pathway
CERVERA_SDHB_TARGETS_1_UP 11866All SZGR genes in this pathway
KANNAN_TP53_TARGETS_UP 5840All SZGR genes in this pathway
TARTE_PLASMA_CELL_VS_PLASMABLAST_UP 398262All SZGR genes in this pathway
ROSS_AML_WITH_MLL_FUSIONS 7845All SZGR genes in this pathway
DER_IFN_GAMMA_RESPONSE_DN 119All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN 408274All SZGR genes in this pathway
KAAB_HEART_ATRIUM_VS_VENTRICLE_UP 249170All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
JIANG_HYPOXIA_NORMAL 311205All SZGR genes in this pathway
CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 528324All SZGR genes in this pathway
BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING 510309All SZGR genes in this pathway
BOQUEST_STEM_CELL_UP 260174All SZGR genes in this pathway
HUPER_BREAST_BASAL_VS_LUMINAL_UP 5429All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
ROSS_LEUKEMIA_WITH_MLL_FUSIONS 7849All SZGR genes in this pathway
VANASSE_BCL2_TARGETS_DN 7450All SZGR genes in this pathway
YAGI_AML_WITH_T_9_11_TRANSLOCATION 13087All SZGR genes in this pathway
YAGI_AML_WITH_11Q23_REARRANGED 351238All SZGR genes in this pathway
PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_DN 2911All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_16 7947All SZGR genes in this pathway
KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP 756494All SZGR genes in this pathway
KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP 682440All SZGR genes in this pathway
CHICAS_RB1_TARGETS_SENESCENT 572352All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_3_DN 3921All SZGR genes in this pathway
AZARE_NEOPLASTIC_TRANSFORMATION_BY_STAT3_UP 12170All SZGR genes in this pathway
LIM_MAMMARY_STEM_CELL_UP 489314All SZGR genes in this pathway
DURAND_STROMA_NS_UP 162103All SZGR genes in this pathway
SMIRNOV_RESPONSE_TO_IR_6HR_UP 16697All SZGR genes in this pathway


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