Summary ?
GeneID9704
SymbolDHX34
SynonymsDDX34|HRH1
DescriptionDEAH-box helicase 34
ReferenceMIM:615475|HGNC:HGNC:16719|Ensembl:ENSG00000134815|HPRD:13144|Vega:OTTHUMG00000149959
Gene typeprotein-coding
Map location19q13.3
Pascal p-value0.624
Sherlock p-value0.646
Fetal beta0.65
eGeneCaudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Frontal Cortex BA9
Meta
SupportAscano FMRP targets

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:GWASdbGenome-wide Association StudiesGWASdb records for schizophrenia
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
KIAA04940.900.85
NEBL0.880.87
ENDOD10.880.84
ERMP10.880.83
SLC12A20.870.73
MAP70.870.85
SEC14L50.870.86
MTMR100.860.70
GALNTL20.860.85
MITF0.860.76
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
NR2C2AP-0.54-0.62
BCL7C-0.54-0.70
ALKBH2-0.53-0.63
EXOSC8-0.52-0.65
NXT1-0.52-0.65
TRNAU1AP-0.52-0.57
RPS19P3-0.52-0.76
CCDC28B-0.52-0.68
C9orf46-0.52-0.66
TUBB2B-0.52-0.60

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER UP 206111All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811508All SZGR 2.0 genes in this pathway
WONG IFNA2 RESISTANCE UP 1610All SZGR 2.0 genes in this pathway
YAGI AML WITH INV 16 TRANSLOCATION 422277All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682433All SZGR 2.0 genes in this pathway