Gene Page: KIAA0355

Summary ?
GeneID9710
SymbolKIAA0355
Synonyms-
DescriptionKIAA0355
ReferenceHGNC:HGNC:29016|Ensembl:ENSG00000166398|HPRD:11077|Vega:OTTHUMG00000180505
Gene typeprotein-coding
Map location19q13.11
Pascal p-value0.146
Sherlock p-value0.762
Fetal beta1.041
DMG1 (# studies)
eGeneMyers' cis & trans

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
DMG:Montano_2016Genome-wide DNA methylation analysisThis dataset includes 172 replicated associations between CpGs with schizophrenia. 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

ProbeChromosomePositionNearest geneP (dis)Beta (dis)FDR (dis)Study
cg074582721934744396KIAA03555.39E-70.010.014DMG:Montano_2016

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs16829545chr2151977407KIAA035597100.02trans
rs10965049chr921526525KIAA035597100.05trans
rs3118341chr925185518KIAA035597100.08trans
rs2393316chr1059333070KIAA035597100.09trans
rs16955618chr1529937543KIAA035597103.352E-4trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
ENTPD60.910.91
GRIN10.900.93
MAN2B20.900.89
DCTN10.890.92
PLD30.890.90
CLSTN30.880.90
SLC25A220.880.90
PTPRN0.880.90
AP001107.10.880.89
IGSF80.880.89
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
GNG11-0.45-0.41
AF347015.21-0.44-0.27
AF347015.18-0.43-0.27
AP002478.3-0.43-0.39
FAM159B-0.43-0.63
RAB13-0.42-0.50
NSBP1-0.42-0.41
AL139819.3-0.41-0.39
MYL12A-0.41-0.44
AL050337.1-0.40-0.39

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
OSMAN BLADDER CANCER DN 406230All SZGR 2.0 genes in this pathway
PATIL LIVER CANCER 747453All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855609All SZGR 2.0 genes in this pathway
PUJANA ATM PCC NETWORK 1442892All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811508All SZGR 2.0 genes in this pathway
KOYAMA SEMA3B TARGETS UP 292168All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS UP 424268All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830547All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP 953554All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783442All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN UP 439257All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL DN 216143All SZGR 2.0 genes in this pathway
VERHAAK GLIOBLASTOMA CLASSICAL 162122All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP 504321All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 19721213All SZGR 2.0 genes in this pathway