Summary ?
GeneID9746
SymbolCLSTN3
SynonymsCDHR14|CSTN3|alcbeta
Descriptioncalsyntenin 3
ReferenceMIM:611324|HGNC:HGNC:18371|Ensembl:ENSG00000139182|HPRD:16725|Vega:OTTHUMG00000168167
Gene typeprotein-coding
Map location12p13.31
Pascal p-value0.019

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
SCN3B0.880.89
DLG20.860.89
PRKCE0.860.92
DLG30.860.88
SCN2A0.860.88
STXBP50.850.91
RIMBP20.850.86
ZC3H12B0.850.84
ARHGEF30.850.85
FRMPD40.850.88
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AP002478.3-0.49-0.60
RAB34-0.48-0.57
FXYD1-0.47-0.51
C11orf67-0.47-0.57
HIGD1B-0.47-0.54
ACSF2-0.46-0.53
C1orf54-0.46-0.58
AC021016.1-0.46-0.52
AC098691.2-0.46-0.60
S100A13-0.46-0.53

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005509calcium ion bindingIEA-
GO:0005515protein bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007155cell adhesionIEA-
GO:0007156homophilic cell adhesionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0045211postsynaptic membraneIEASynap, Neurotransmitter (GO term level: 5)-
GO:0000139Golgi membraneIEA-
GO:0005794Golgi apparatusIEA-
GO:0005789endoplasmic reticulum membraneIEA-
GO:0005783endoplasmic reticulumIEA-
GO:0016021integral to membraneIEA-
GO:0005886plasma membraneIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
KORKOLA YOLK SAC TUMOR UP 2014All SZGR 2.0 genes in this pathway
RODRIGUES DCC TARGETS DN 12184All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP 182110All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS UP 14984All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142669All SZGR 2.0 genes in this pathway
LEIN NEURON MARKERS 6945All SZGR 2.0 genes in this pathway
MIKKELSEN MEF LCP WITH H3K27ME3 7035All SZGR 2.0 genes in this pathway
MIKKELSEN IPS LCP WITH H3K4ME3 174100All SZGR 2.0 genes in this pathway
MIKKELSEN ES LCP WITH H3K4ME3 14280All SZGR 2.0 genes in this pathway