Summary ?
GeneID9912
SymbolARHGAP44
SynonymsNPC-A-10|RICH2
DescriptionRho GTPase activating protein 44
ReferenceHGNC:HGNC:29096|Ensembl:ENSG00000006740|HPRD:13810|Vega:OTTHUMG00000058765
Gene typeprotein-coding
Map location17p12
Pascal p-value4.095E-5
Sherlock p-value0.931

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
EZH10.840.87
WDR42A0.820.81
PNMA30.810.82
SGSM10.800.83
HACE10.800.84
MAN2A20.800.83
SPATA20.800.81
MAPK8IP30.800.83
KLHL30.790.82
COG10.790.84
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
GNG11-0.51-0.60
IL32-0.51-0.59
DBI-0.51-0.59
MYL12A-0.50-0.58
AF347015.21-0.49-0.47
CLEC3B-0.48-0.58
IGFBP7-0.48-0.57
C1orf54-0.48-0.55
RHOC-0.48-0.57
S100A16-0.47-0.50

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
REACTOME SIGNALING BY RHO GTPASES 11381All SZGR 2.0 genes in this pathway
HUTTMANN B CLL POOR SURVIVAL UP 276187All SZGR 2.0 genes in this pathway
BORCZUK MALIGNANT MESOTHELIOMA DN 10459All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584356All SZGR 2.0 genes in this pathway
PEREZ TP53 TARGETS 1174695All SZGR 2.0 genes in this pathway
MOREAUX MULTIPLE MYELOMA BY TACI UP 412249All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 20HR UP 240152All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 720440All SZGR 2.0 genes in this pathway
MEISSNER NPC HCP WITH H3K4ME3 AND H3K27ME3 142103All SZGR 2.0 genes in this pathway
WANG RESPONSE TO GSK3 INHIBITOR SB216763 DN 374217All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 1 UP 12561All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 2 UP 5431All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 3 UP 17097All SZGR 2.0 genes in this pathway