deTS Results for Major dietary changes in the last 5 years: No

Traits Information:

Trait ID:

1383

1538_0
Major dietary changes in the last 5 years: No
UK Biobank (UKBB)
Neale Lab, 2018
# cases = 221368 | # controls = 138926
# SNPs = 13586568 | # genes = 21889
1.145
p (gene) < 0.05:  # TAGs = 3324
p (gene) < 0.01:  # TAGs = 1419
p (gene) < 0.001:  # TAGs = 571
p (gene) < 1.0E-4:  # TAGs = 222
p (gene) < 1.0E-5:  # TAGs = 116

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.01 p < 0.001 p < 1.0E-4 p < 1.0E-5 0.9540.7990.5730.750.1790.01690.08440.03390.1420.1790.2230.2720.03390.2230.04680.08440.110.4460.7990.005210.5730.007840.6360.005210.750.2720.7990.2230.880.08440.04680.9980.3850.9690.9350.9540.6360.9350.7990.5730.1770.2230.3850.8430.3850.750.01690.9790.9790.740.550.450.02290.09350.06080.01330.02290.270.1970.02290.09350.09350.06080.02290.3550.9280.00210.740.450.270.450.740.9280.9280.1970.9790.270.1970.9280.450.9790.8180.9280.8180.8180.8810.8180.060.007460.8810.8180.1970.8180.007460.9610.6370.7840.4750.4750.01320.06090.02950.01320.02950.2030.1160.01320.2030.06090.02950.1160.2030.8950.3250.7840.6370.1160.6370.7840.3250.3250.3250.4750.3250.4750.8950.6370.8950.8950.7840.2030.9610.9610.990.3230.7840.8950.6370.4750.4750.6370.6680.2520.6680.2520.4440.05260.1240.05260.1240.2520.2520.2520.1240.2520.1240.05260.1240.2520.4440.2520.6680.4440.1240.6680.6680.4440.4440.6680.8610.2520.4440.8610.4440.8610.970.6680.4441.00.970.970.6670.970.8610.4440.8610.4440.668Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.01 p < 0.001 p < 1.0E-4 p < 1.0E-5 0.9990.9980.3980.5920.8580.8160.7070.1120.08490.1460.990.5270.1420.4620.002080.5920.02420.7140.9220.03420.1460.03270.4620.2280.1120.4620.1850.7680.3381.00.7070.9220.8580.4580.3340.8140.9220.9740.03420.4620.8930.9990.8580.8161.00.8970.2050.8380.7620.5710.6670.6690.3680.2810.940.6710.4640.2050.370.03860.5710.9681.00.09630.6710.06060.4690.06140.09520.6710.2050.6710.370.9980.4640.9680.2810.2790.5690.6690.6710.8384.74E-40.7620.8981.00.9930.8380.9870.950.5880.5880.2770.4230.0890.4220.02060.02080.950.2770.7440.04520.5880.1660.8720.7460.950.02080.1660.02040.5880.4220.08970.5880.7460.7460.4230.9980.7440.950.2770.04480.8710.950.7460.9870.5880.7460.8720.9980.950.950.9620.9620.6250.8350.6250.3960.3940.6240.09780.01371.00.03930.6230.09830.3960.09830.6250.6250.9620.09830.2130.6230.9620.8350.2120.2130.8350.2130.2131.00.6231.00.3960.09781.00.8350.3960.8350.8350.8350.6251.00.6250.962Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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