deTS Results for Forearm Bone Mineral Density

Traits Information:

Trait ID:

4820

Bone Mineral Density
Forearm Bone Mineral Density
Expanded Trait Collection (ETC)
Zheng, 2015
26367794
# cases = 0 | # controls = 6627
# SNPs = 9100068 | # genes = 22056
1.015
p (gene) < 0.05:  # TAGs = 1303
p (gene) < 0.01:  # TAGs = 323
p (gene) < 0.001:  # TAGs = 42
p (gene) < 1.0E-4:  # TAGs = 8
p (gene) < 1.0E-5: # TAGs = 3

Manhattan Plot of All SNPs in the GWAS




Manhattan Plot of All Genes in the GWAS


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deTS Enrichment Analysis Using the GTEx Panel


p < 0.05 p < 0.01 p < 0.001 0.4260.7390.09670.0392.0E-40.7910.6820.490.4260.490.620.620.7390.4260.2510.5560.9540.7910.2510.02770.8370.490.7390.490.3050.05380.6820.07280.490.4260.8370.5560.5560.2030.07285.75E-40.6820.07280.7910.4260.8740.3630.9680.0390.05380.09670.1620.9080.2580.06390.06390.002070.7340.3650.3650.4870.4870.3650.4870.6140.7340.3650.3650.9080.7340.3650.1080.8340.1720.3650.2580.6140.4870.7340.1720.3650.4870.6140.3650.6140.7340.03580.2580.7340.002070.4870.3650.8330.7340.9820.06390.1080.1720.1080.480.8070.07350.004540.07350.07350.02020.2140.2140.2140.07350.07350.07350.480.2140.2140.8070.480.481.00.480.481.00.8071.00.8070.8070.2141.00.02020.481.00.480.480.2140.480.8070.8070.480.480.8061.00.480.480.2140.8070.807Adipose - SubcutaneousAdipose - Visceral (Omentum)Artery - AortaArtery - CoronaryArtery - TibialBrain - AmygdalaBrain - Anterior cingulate cortex (BA24)Brain - Caudate (basal ganglia)Brain - Cerebellar HemisphereBrain - CerebellumBrain - CortexBrain - Frontal Cortex (BA9)Brain - HippocampusBrain - HypothalamusBrain - Nucleus accumbens (basal ganglia)Brain - Putamen (basal ganglia)Brain - Spinal cord (cervical c-1)Brain - Substantia nigraBreast - Mammary TissueColon - SigmoidColon - TransverseEsophagus - Gastroesophageal JunctionEsophagus - MucosaEsophagus - MuscularisStomachHeart - Atrial AppendageHeart - Left VentricleAdrenal GlandKidney-CortexLiverLungMinor Salivary GlandMuscle - SkeletalNerve - TibialOvaryPancreasPituitaryProstateSkin - Not Sun Exposed (Suprapubic)Skin - Sun Exposed (Lower leg)Small Intestine - Terminal IleumSpleenTestisThyroidUterusVaginaWhole Blood

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deTS Enrichment Analysis Using the ENCODE Panel


p < 0.05 p < 0.01 p < 0.001 0.7960.9370.2990.9380.9720.6210.6140.4840.7930.6210.4220.9380.06490.7430.2990.4880.1960.2440.09070.5550.1550.2380.04920.03450.1940.3580.6210.001220.6210.03520.150.1960.007620.4840.1940.6810.7430.2440.8810.9930.09070.4880.4220.8420.5350.6630.1220.9910.5350.7810.0710.0210.1930.4060.1940.9360.1910.8730.2890.5350.5350.4060.4060.9360.6650.1910.1220.004930.2880.1940.7810.5350.7810.4060.4020.1220.2890.5330.1930.7790.9360.02130.9730.9980.1940.7810.2890.6650.4450.7840.1861.00.7840.7840.4430.05970.1860.4451.01.00.4431.00.4451.00.7840.7840.1861.01.00.4430.4455.46E-40.1860.7841.00.4450.7841.00.7840.4450.7840.7840.7840.7840.7840.05991.00.7840.4451.00.4450.186Subcutaneous Adipose TissueOmental Fat PadThoracic AortaCerebellumFrontal CortexSpinal CordOccipital LobeParietal LobeTemporal LobeDiencephalonBreast EpitheliumCamera type eyeSigmoid ColonTransverse ColonEsophagus Muscularis MucosaEsophagus Squamous EpitheliumGastroesophageal SphincterStomachHeartHeart - Left VentricleRight Atrium Auricular RegionAdrenal GlandMetanephrosLiverRight Lobe of LiverLungUpper Lobe of Left LungSkeletal Muscle TissueGastrocnemius MedialisTongueTibial NerveOvaryBody of PancreasPeyer's PatchProstate GlandSuprapubic SkinLower Leg SkinSkin of BodySpleenTestisThyroid GlandUmbilical CordUrinary BladderUterus

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