Gene expression
Obtain a pan-cancer view on the gene expression in 11 TCGA cancer types.
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Somatic mutations
View the mutational features in multiple cancers.
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Pan-cancer Analysis
Check out how many common tumor suppressors are available for multiple cancers.
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Literature
Inquire into the curated literature about tumor suppressor in various cancers.
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Biological Network
Explore what are the relevant regulators based on our curated tumor suppressor genes.
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Literature-based knowledgebase
TSGene 2.0 is a comprehensive resource for pan-cancer analysis of human tumor suppressor genes (TSGs). It includes:
- Literature data
- Long non-coding tumor suppressor genes
- Curated tumor suppressor microRNAs
- Pan-cancer variants
- Pan-cancer gene expression profiles
- Regulatory information
- Biological pathways
- 572 newly reported tumor suppressor genes including 19 long non-coding RNAs were added to TSGene 2.0.
- The down-regulated tumor suppressor genes commonly observed 11 cancer types from TCGA pan-cancer project were added to TSGene 2.0.
Statistics of TSGene 2.0
- 1217 human TSGs (1018 protein-coding and 199 non-coding genes).
- 3354 curated PubMed abstracts.
- 1,210,544 genetic mutations from various types of cancers.
