Pulmonary Arterial Hypertension KnowledgeBase (bioinfom_tsdb)
bioinfom_tsdb
Pulmonary Arterial Hypertension KnowledgeBase

Found 81 literature records

Page :1 2
Entrez IDDescription
1029Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
375Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
1029Loss of heterozygosity at the proximal-mid part of mouse chromosome 4 defines two novel tumor suppressor gene loci in T-cell lymphomas.
1030Loss of heterozygosity at the proximal-mid part of mouse chromosome 4 defines two novel tumor suppressor gene loci in T-cell lymphomas.
8915These data suggest that wild-type BCL10 may act as a tumor suppressor.
27086The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
1029p14(ARF) nuclear overexpression in aggressive B-cell lymphomas is a sensor of malfunction of the common tumor suppressor pathways.
5728Primary malignant lymphoma of the brain: analysis of MMAC1 (PTEN) tumor suppressor gene.
1029Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous B cell lymphoma.
1030Inactivation of tumor suppressor genes p15(INK4b) and p16(INK4a) in primary cutaneous B cell lymphoma.
5728Negative feedback regulation of the tumor suppressor PTEN by phosphoinositide-induced serine phosphorylation.
1029ATM and the ARF-p53 tumor suppressor pathway may cooperate in the pathogenesis of diffuse large B-cell lymphoma
5934Expression of RB2/p130 tumor-suppressor gene in AIDS-related non-Hodgkin's lymphomas: implications for disease pathogenesis.
7157investigated whether Tat might alter p53 acetylation and p53-responsive transcription; results allude to mechanism where the HIV-1 trans-activator might impair tumor suppressor functions favoring establishment of neoplasia in AIDS
1027deregulation of control mechanisms at G1/S transition by combination of high cyclin E levels in the absence of p27(Kip1) is sufficient to predispose mice to develop lymphoid malignancies and further support a role of p27(Kip1) as a tumor suppressor
5629PROX1 gene corresponds to that of a candidate tumor-suppressor gene.
122953c-Jun dimerization protein 2 inhibits cell transformation and has a role as a tumor suppressor gene
5655"The normal epithelial cell-specific 1 (NES1) gene, a candidate tumor suppressor gene on chromosome 19q13.3-4, is downregulated by hypermethylation in acute lymphoblastic leukemia."
1031"p18INK4c may function as a tumor suppressor in Hodgkin lymphoma, and inactivation may contribute to cell cycle deregulation and defective terminal differentiation of the Reed-Sternberg cells."
7474Wnt5a inhibits B cell proliferation and functions as a tumor suppressor in hematopoietic tissue.
355Tumor suppressor gene regions responsible for lymphomagenesis might not considerably differ due to the Fas gene status.
5371Loss of the tumor suppressor PML in human cancers of multiple histologic origins.
80198studies demonstrate a critical role for the proper biallelic expression of the mammalian Mus81 in the maintenance of genomic integrity and tumor suppression
6091Dutt1/Robo1 is a classic tumor suppressor gene requiring inactivation of both alleles to elicit lung tumorigenesis in these mice.
1029Primary malignant lymphoma of the brain: frequent abnormalities and inactivation of p14 tumor suppressor gene.
5777STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.
10912Results show that GADD45G can act as a functional new-age tumor suppressor but being frequently inactivated epigenetically in multiple tumors.
3621the suggested role of ing1 as a candidate tumor suppressor gene involved in control of DNA damage response.
9937Snm1 is a tumor suppressor in mice that in addition has a role in immunity
639identifies PRDM1 inactivation as a recurrent genetic defect in diffuse large B-cell lymphomas cells and establishes PRDM1 as a potential tumor suppressor gene.
639"Blimp1 is a tumor suppressor gene, whose inactivation may contribute to lymphomagenesis by blocking post-germinal center differentiation of B cells toward plasma cells."
8651Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation
5783The PTPN13 protein has proapoptotic functions and can fuction as TSGs to suppress tumorigenesis.
9314The work identifies KLF4 as a putative tumor suppressor in B-cell malignancies.
1029Regulation of the Arf tumor suppressor in Emicro-Myc transgenic mice: longitudinal study of Myc-induced lymphomagenesis.
51741analysis in mice shows that WWOX has a tumor suppressor function
9411PARG1 expression was substantially reduced & it displayed at least partial promoter methylation in all investigated mantle-cell lines & in 31 primary cases. PARG1 is a strong candidate tumor suppressor gene in MCL.
1026P21(WAF1/CIP1) may be a tumor suppressor after all.
51741Wwox hypomorphs had an increased incidence of B-cell lymphomas supports a role of Wwox as a tumor suppressor
8651mediastinal B-cell lymphoma and hodgkin lymphoma cells share overlapping features and defective tumor suppressor gene SOCS-1 triggers an oncogenic pathway operative in both Hodgkin and non-Hodgkin lymphomas.
6776Acts as a key tumor suppressor by reciprocally inhibiting expression of oncogenic nucleophosmin (NPM)-anaplastic lymphoma kinase (ALK) in T-cell anaplastic large cell lymphomas.
10395"Tumor-specific methylation of the 8p22 tumor suppressor gene DLC1 is an epigenetic biomarker for Hodgkin, nasal NK/T-cell and other types of lymphomas."
100132074FoxO factors mediate Myc-induced Arf expression and provide direct genetic evidence for their tumor-suppressive capacity.
3090Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma
7157Detailed mapping of chromosome 17p deletions reveals HIC1 as a novel tumor suppressor gene candidate telomeric to TP53 in diffuse large B-cell lymphoma
8651SOCS-1 mutations qualify as a tumor suppressor in mediastinal b-cell lymphoma.
8795Thus TRAIL-R may function as an inflammation and tumor suppressor in multiple tissues in vivo.
1326"Tpl2, a potent oncogene, functions as a tumor suppressor gene in chronically stimulated T cells."
90427Bmf plays a critical role in apoptosis signaling and can function as a tumor suppressor.
639PRDM1 may be a tumor suppressor in some primary central nervous system lymphoma and contribute to lymphomagenesis by impairing terminal differentiation


')