TissGeneSummary for ZNF560 |
Gene summary |
Basic gene information | Gene symbol | ZNF560 |
Gene name | zinc finger protein 560 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 19p13.2 | |
Type of gene | protein-coding | |
RefGenes | NM_152476.2, | |
Description | - | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Ensembl : ENSG00000198028 | ||
HPRD : 15842 | ||
Vega : OTTHUMG00000180130 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_ZNF560 | |
BioGPS: 147741 | ||
Pathway | NCI Pathway Interaction Database: ZNF560 | |
KEGG: ZNF560 | ||
REACTOME: ZNF560 | ||
Pathway Commons: ZNF560 | ||
Context | iHOP: ZNF560 | |
ligand binding site mutation search in PubMed: ZNF560 | ||
UCL Cancer Institute: ZNF560 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of ZNF560 | ||
Description by TissGene annotations | Cancer gene |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for ZNF560 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
THCA | 0.719987728 | -1.157174984 | 1.877162712 | 4.76E-08 | 2.16E-07 |
PRAD | 0.941319736 | -0.968162956 | 1.909482692 | 3.60E-05 | 0.000169844 |
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TissGene-miRNA for ZNF560 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for ZNF560 |
TissGeneSNV for ZNF560 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.W178* | SKCM | 5 |
p.S692F | SKCM | 3 |
p.R592Q | SKCM | 3 |
p.R694Q | SKCM | 3 |
p.E212K | SKCM | 2 |
p.Q304* | SKCM | 2 |
p.R694Q | UCEC | 2 |
p.R536Q | UCEC | 2 |
p.R732Q | SKCM | 2 |
p.G764E | SKCM | 2 |
p.G606E | SKCM | 2 |
p.G690E | SKCM | 2 |
p.Q10* | SKCM | 2 |
p.R702C | UCEC | 2 |
p.E464K | SKCM | 1 |
p.W322L | LUAD | 1 |
p.R612C | PAAD | 1 |
p.D128N | SARC | 1 |
p.G764R | SKCM | 1 |
p.A688T | STAD | 1 |
p.D726Y | READ | 1 |
p.R532C | SKCM | 1 |
p.F497I | LUAD | 1 |
p.F516L | KIRC | 1 |
p.S666R | HNSC | 1 |
p.E293K | SKCM | 1 |
p.K713R | READ | 1 |
p.H762D | LUSC | 1 |
p.S315N | LUAD | 1 |
p.D289H | THCA | 1 |
p.R755C | UCEC | 1 |
p.S114R | COAD | 1 |
p.R620Q | SKCM | 1 |
p.R238* | LUAD | 1 |
p.R620* | BRCA | 1 |
p.G456R | SKCM | 1 |
p.L559I | UCEC | 1 |
p.K657T | BLCA | 1 |
p.H510Q | BLCA | 1 |
p.E573K | SKCM | 1 |
p.D632N | SKCM | 1 |
p.S315N | UCEC | 1 |
p.R750C | BRCA | 1 |
p.R750S | LUAD | 1 |
p.E211K | LUAD | 1 |
p.G150_splice | OV | 1 |
p.L307F | SKCM | 1 |
p.R564Q | COAD | 1 |
p.W81* | LUAD | 1 |
p.R702C | SKCM | 1 |
p.A427T | COAD | 1 |
p.R694Q | LGG | 1 |
p.M575L | STAD | 1 |
p.C658Y | SKCM | 1 |
p.K713R | UCEC | 1 |
p.G294C | BRCA | 1 |
p.R702C | BRCA | 1 |
p.R612L | LUSC | 1 |
p.Q304X | SKCM | 1 |
p.S12F | SKCM | 1 |
p.S641Y | LUSC | 1 |
p.Q281X | SKCM | 1 |
p.S273C | LIHC | 1 |
p.G372E | UCEC | 1 |
p.R39K | LUAD | 1 |
p.R206I | READ | 1 |
p.E352K | SKCM | 1 |
p.P388L | STAD | 1 |
p.F516Y | SKCM | 1 |
p.G405R | SARC | 1 |
p.L229P | STAD | 1 |
p.L619V | STAD | 1 |
p.L175F | SKCM | 1 |
p.L447V | BLCA | 1 |
p.R694Q | BLCA | 1 |
p.L392P | UCS | 1 |
p.R694Q | LUAD | 1 |
p.S12F | BLCA | 1 |
p.N133S | SKCM | 1 |
p.C658* | SKCM | 1 |
p.D250N | SKCM | 1 |
p.A130D | UCEC | 1 |
p.K676Q | STAD | 1 |
p.V337E | KICH | 1 |
p.R620Q | UCEC | 1 |
p.Q94L | LUAD | 1 |
p.S752F | SKCM | 1 |
p.K579N | BLCA | 1 |
p.W27X | COAD | 1 |
p.S527F | HNSC | 1 |
p.C546Y | LGG | 1 |
p.R783C | SKCM | 1 |
p.S259C | BLCA | 1 |
p.T705I | SKCM | 1 |
p.E166K | SKCM | 1 |
p.Y348F | LUSC | 1 |
p.A785T | ESCA | 1 |
p.E243K | SKCM | 1 |
p.R532S | THYM | 1 |
p.R487C | STAD | 1 |
p.A567V | PRAD | 1 |
p.A205_splice | GBM | 1 |
p.T751K | SKCM | 1 |
p.D614H | LUSC | 1 |
p.T330S | COAD | 1 |
p.E68Q | LUSC | 1 |
p.R732Q | BLCA | 1 |
p.M233V | LGG | 1 |
p.T509N | UCEC | 1 |
p.R732Q | UCEC | 1 |
p.L278S | SKCM | 1 |
p.G372E | LGG | 1 |
p.H454Y | SKCM | 1 |
p.S90L | SKCM | 1 |
p.L37V | COAD | 1 |
p.L158M | LUAD | 1 |
p.G201W | HNSC | 1 |
p.R760K | SKCM | 1 |
p.P360H | LUSC | 1 |
p.Q55* | SKCM | 1 |
p.N193T | ESCA | 1 |
p.H335Y | LUSC | 1 |
p.T23S | READ | 1 |
p.N659I | SKCM | 1 |
p.Q55H | HNSC | 1 |
p.R584S | LUAD | 1 |
p.Q34L | LUSC | 1 |
p.R702H | UCEC | 1 |
p.Y558C | LUAD | 1 |
p.A505T | LGG | 1 |
p.Q10X | SKCM | 1 |
p.K374R | SKCM | 1 |
p.R532H | ESCA | 1 |
p.E321V | COAD | 1 |
p.H506D | HNSC | 1 |
p.R206I | UCEC | 1 |
p.A309T | STAD | 1 |
p.K788N | STAD | 1 |
p.W27* | SKCM | 1 |
p.D716E | UCEC | 1 |
p.K411N | UVM | 1 |
p.R206I | CHOL | 1 |
p.E765D | HNSC | 1 |
p.N691H | CESC | 1 |
p.G474S | SKCM | 1 |
p.S114N | LUSC | 1 |
p.E573* | UCEC | 1 |
p.P388L | LUAD | 1 |
p.E597* | UCEC | 1 |
p.R702C | LGG | 1 |
p.R694Q | STAD | 1 |
p.R593S | SKCM | 1 |
p.S781* | BLCA | 1 |
p.T683P | UCEC | 1 |
p.A412P | STAD | 1 |
p.Q304K | ESCA | 1 |
p.G512V | LUSC | 1 |
p.S157I | UCEC | 1 |
p.H790Q | LUAD | 1 |
p.Q281* | SKCM | 1 |
p.R592Q | COAD | 1 |
p.R396Q | UCEC | 1 |
p.V731M | COAD | 1 |
p.E68K | SKCM | 1 |
p.M763L | SKCM | 1 |
p.K603N | UCEC | 1 |
p.R760I | UCEC | 1 |
p.V77F | PRAD | 1 |
p.S473L | BLCA | 1 |
p.T369I | SKCM | 1 |
p.E597X | READ | 1 |
p.E681G | LIHC | 1 |
p.C658X | SKCM | 1 |
p.C195F | DLBC | 1 |
p.E317* | UCEC | 1 |
p.P627L | SKCM | 1 |
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TissGeneCNV for ZNF560 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for ZNF560 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for ZNF560 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for ZNF560 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for ZNF560 |
TissGeneDrug for ZNF560 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for ZNF560 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |