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| TissGeneSummary for CTNND2 |
 Gene summary |
| Basic gene information | Gene symbol | CTNND2 |
| Gene name | catenin (cadherin-associated protein), delta 2 | |
| Synonyms | GT24|NPRAP | |
| Cytomap | UCSC genome browser: 5p15.2 | |
| Type of gene | protein-coding | |
| RefGenes | NM_001288715.1, NM_001288716.1,NM_001288717.1,NM_001332.3,NR_109988.1, | |
| Description | T-cell delta-catenincatenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)catenin delta-2neurojungin | |
| Modification date | 20141222 | |
| dbXrefs | MIM : 604275 | |
| HGNC : HGNC | ||
| Ensembl : ENSG00000169862 | ||
| HPRD : 09181 | ||
| Vega : OTTHUMG00000090511 | ||
| Protein | UniProt: go to UniProt's Cross Reference DB Table | |
| Expression | CleanEX: HS_CTNND2 | |
| BioGPS: 1501 | ||
| Pathway | NCI Pathway Interaction Database: CTNND2 | |
| KEGG: CTNND2 | ||
| REACTOME: CTNND2 | ||
| Pathway Commons: CTNND2 | ||
| Context | iHOP: CTNND2 | |
| ligand binding site mutation search in PubMed: CTNND2 | ||
| UCL Cancer Institute: CTNND2 | ||
| Assigned class in TissGDB* | C | |
| Included tissue-specific gene expression resources | HPA,TiGER | |
| Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Brain | |
| Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | GBM,LGG | |
| Reference showing the relevant tissue of CTNND2 | ||
| Description by TissGene annotations | Protective TissGene in OS Have significant anti-correlated miRNA Fused withTSGene | |
| * Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
| Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
| GO ID | GO term | PubMed ID |
| Top |
| TissGeneExp for CTNND2 |
| Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
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| Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
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| Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
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| Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
 |
| - Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
| Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
| KIRC | -3.992072165 | -2.210831887 | -1.781240278 | 7.41E-23 | 7.25E-22 |
| COAD | -3.75701522 | -0.347442144 | -3.409573077 | 8.80E-16 | 7.14E-14 |
| LUAD | -2.367039358 | 1.084653745 | -3.451693103 | 5.17E-12 | 3.74E-11 |
| PRAD | 2.848373241 | 1.161942472 | 1.686430769 | 2.03E-09 | 2.90E-08 |
| KIRP | -3.63997772 | -1.791537095 | -1.848440625 | 5.17E-07 | 2.81E-06 |
| LUSC | -3.097884828 | 0.727821054 | -3.825705882 | 1.54E-16 | 1.16E-15 |
| STAD | -1.70000897 | -0.32125897 | -1.37875 | 0.00482 | 0.018722245 |
| LIHC | -2.12283522 | -0.53797322 | -1.584862 | 0.0058 | 0.013131295 |
| ESCA | -4.071347039 | -0.283119766 | -3.788227273 | 3.73E-05 | 0.001639655 |
| HNSC | -3.986448941 | -2.583232662 | -1.403216279 | 0.000205 | 0.000838636 |
| Top |
| TissGene-miRNA for CTNND2 |
| Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
| Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
| LUAD | hsa-miR-200b-3p | MIMAT0000318 | 0.024 | -0.29 | 60 |
| LUAD | hsa-miR-429 | MIMAT0001536 | 0.019 | -0.3 | 60 |
| Top |
| TissGeneMut for CTNND2 |
| TissGeneSNV for CTNND2 |
| nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
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| Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
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| - nsSNVs sorted by frequency. |
| AAchange | Cancer type | # samples |
| p.S772L | SKCM | 3 |
| p.E797K | LUAD | 2 |
| p.R917W | LIHC | 2 |
| p.D1168N | SKCM | 2 |
| p.K1192T | STAD | 2 |
| p.E57K | SKCM | 2 |
| p.L873V | STAD | 2 |
| p.P1206S | SKCM | 2 |
| p.H449N | HNSC | 1 |
| p.C910F | LUAD | 1 |
| p.V825L | BLCA | 1 |
| p.S373C | LUAD | 1 |
| p.P835Q | LUSC | 1 |
| p.T1194A | UCEC | 1 |
| p.A615D | READ | 1 |
| p.G800D | SKCM | 1 |
| p.P316L | LUAD | 1 |
| p.G86R | COAD | 1 |
| p.V888L | HNSC | 1 |
| p.Q505H | LUAD | 1 |
| p.S93N | LUAD | 1 |
| p.P515S | STAD | 1 |
| p.S517I | LUAD | 1 |
| p.R531T | HNSC | 1 |
| p.A978G | LUAD | 1 |
| p.R82Q | BLCA | 1 |
| p.L35S | STAD | 1 |
| p.P1206L | SKCM | 1 |
| p.A570V | LGG | 1 |
| p.P533Q | HNSC | 1 |
| p.R889* | CESC | 1 |
| p.A980V | LUSC | 1 |
| p.S312R | LUAD | 1 |
| p.A954S | ESCA | 1 |
| p.E146X | READ | 1 |
| p.A412P | HNSC | 1 |
| p.A680E | LUAD | 1 |
| p.Q557X | SKCM | 1 |
| p.G473V | LUAD | 1 |
| p.V746M | UCEC | 1 |
| p.E513* | UCEC | 1 |
| p.E116V | LUAD | 1 |
| p.A24T | BLCA | 1 |
| p.G637V | STAD | 1 |
| p.R734* | STAD | 1 |
| p.L307Q | LIHC | 1 |
| p.A1130V | UCS | 1 |
| p.I1059M | HNSC | 1 |
| p.A383T | SKCM | 1 |
| p.L794R | HNSC | 1 |
| p.R702L | LUAD | 1 |
| p.Y399* | SKCM | 1 |
| p.D541E | STAD | 1 |
| p.M840I | LIHC | 1 |
| p.G998E | SKCM | 1 |
| p.N582H | LUSC | 1 |
| p.H476Q | HNSC | 1 |
| p.A915V | PRAD | 1 |
| p.Q557* | SKCM | 1 |
| p.T649S | HNSC | 1 |
| p.E607K | READ | 1 |
| p.P524L | BLCA | 1 |
| p.R885* | HNSC | 1 |
| p.G985S | BRCA | 1 |
| p.A483V | LUAD | 1 |
| p.S91I | LUAD | 1 |
| p.L679P | THCA | 1 |
| p.R732K | SKCM | 1 |
| p.P422S | SKCM | 1 |
| p.D757Y | THYM | 1 |
| p.L150M | LUSC | 1 |
| p.L410V | STAD | 1 |
| p.L854P | LUAD | 1 |
| p.E1148K | SKCM | 1 |
| p.S373G | STAD | 1 |
| p.E57G | SKCM | 1 |
| p.C910* | HNSC | 1 |
| p.R1047Q | ACC | 1 |
| p.E804D | COAD | 1 |
| p.A572G | LUAD | 1 |
| p.Q557K | LUAD | 1 |
| p.R610G | LUAD | 1 |
| p.P169L | HNSC | 1 |
| p.V761I | UCEC | 1 |
| p.R730S | LUAD | 1 |
| p.K989T | STAD | 1 |
| p.G865W | LUAD | 1 |
| p.G297S | LIHC | 1 |
| p.C910W | ACC | 1 |
| p.L1022V | BRCA | 1 |
| p.S696L | HNSC | 1 |
| p.R982W | STAD | 1 |
| p.T716I | SKCM | 1 |
| p.E59K | SKCM | 1 |
| p.R734X | STAD | 1 |
| p.T47A | STAD | 1 |
| p.T198M | HNSC | 1 |
| p.S696X | READ | 1 |
| p.R411W | PAAD | 1 |
| p.S333L | SKCM | 1 |
| p.A71T | HNSC | 1 |
| p.P550S | SKCM | 1 |
| p.P1066S | SKCM | 1 |
| p.A612V | STAD | 1 |
| p.T48N | LUAD | 1 |
| p.D668N | UCEC | 1 |
| p.L121I | BLCA | 1 |
| p.L682M | LUAD | 1 |
| p.S342F | LIHC | 1 |
| p.A71T | GBM | 1 |
| p.E409G | STAD | 1 |
| p.R1063C | CESC | 1 |
| p.L632M | LUAD | 1 |
| p.V428I | COAD | 1 |
| p.R702Q | BLCA | 1 |
| p.Q132K | LUAD | 1 |
| p.Q479E | HNSC | 1 |
| p.C736* | LIHC | 1 |
| p.D650H | CESC | 1 |
| p.V566I | SKCM | 1 |
| p.K890N | SKCM | 1 |
| p.R1179H | SARC | 1 |
| p.G40R | SKCM | 1 |
| p.D757N | SKCM | 1 |
| p.R504* | BLCA | 1 |
| p.Q430X | SKCM | 1 |
| p.P495Q | LUAD | 1 |
| p.C910F | BRCA | 1 |
| p.R730C | SKCM | 1 |
| p.I588R | BLCA | 1 |
| p.R902Q | STAD | 1 |
| p.G792E | SKCM | 1 |
| p.G752R | COAD | 1 |
| p.R902Q | LUAD | 1 |
| p.A725T | LGG | 1 |
| p.G181A | HNSC | 1 |
| p.E526Q | LUAD | 1 |
| p.A286T | UCEC | 1 |
| p.S724L | BLCA | 1 |
| p.D922G | STAD | 1 |
| p.G876W | THCA | 1 |
| p.R129K | LUAD | 1 |
| p.D1029N | SKCM | 1 |
| p.E46K | SKCM | 1 |
| p.R427C | HNSC | 1 |
| p.Q1011K | KIRC | 1 |
| p.S708L | SKCM | 1 |
| p.Q507* | HNSC | 1 |
| p.R1047Q | KIRP | 1 |
| p.A685E | HNSC | 1 |
| p.D650H | LUAD | 1 |
| p.R1063C | STAD | 1 |
| p.S23L | LUSC | 1 |
| p.E513K | BLCA | 1 |
| p.E409G | ESCA | 1 |
| p.S30F | SKCM | 1 |
| p.G998V | LUAD | 1 |
| p.Q58K | BLCA | 1 |
| p.Y491C | LUAD | 1 |
| p.A500T | BLCA | 1 |
| p.L967M | LUAD | 1 |
| p.S333L | STAD | 1 |
| p.G726R | SKCM | 1 |
| p.S32N | LIHC | 1 |
| p.V512D | LUAD | 1 |
| p.V1145G | PAAD | 1 |
| p.G865V | LIHC | 1 |
| p.P345S | SKCM | 1 |
| p.V428I | HNSC | 1 |
| p.Q153H | BLCA | 1 |
| p.P21H | LUAD | 1 |
| p.P446L | STAD | 1 |
| p.R702W | SKCM | 1 |
| p.I535T | LUSC | 1 |
| p.S1121X | ESCA | 1 |
| p.G837R | SKCM | 1 |
| p.G636S | LUSC | 1 |
| p.L445V | LUAD | 1 |
| p.E1133K | SKCM | 1 |
| p.T28M | COAD | 1 |
| p.Q110H | STAD | 1 |
| p.R935* | HNSC | 1 |
| p.S1150R | LUSC | 1 |
| p.G726V | LIHC | 1 |
| p.A484V | SKCM | 1 |
| p.G34S | LUAD | 1 |
| p.L651M | SKCM | 1 |
| p.D757H | LUSC | 1 |
| p.E133* | LUAD | 1 |
| p.P444L | SKCM | 1 |
| p.V428I | LUAD | 1 |
| p.Q1161E | THCA | 1 |
| p.Q470* | HNSC | 1 |
| p.R889* | LUSC | 1 |
| p.C910* | LUAD | 1 |
| p.A1097T | COAD | 1 |
| p.S91N | STAD | 1 |
| p.P860L | SKCM | 1 |
| p.A570V | SARC | 1 |
| p.V512I | LUAD | 1 |
| p.E122K | LUSC | 1 |
| p.R396Q | SKCM | 1 |
| p.I929V | HNSC | 1 |
| p.T382M | STAD | 1 |
| p.E1105K | COAD | 1 |
| p.D999E | GBM | 1 |
| p.V746M | HNSC | 1 |
| p.L661F | SKCM | 1 |
| p.R889X | SKCM | 1 |
| p.M934R | PRAD | 1 |
| p.T787M | STAD | 1 |
| p.G614R | SKCM | 1 |
| p.G473C | LUAD | 1 |
| p.Q487H | HNSC | 1 |
| p.A685V | UCEC | 1 |
| p.L981* | SKCM | 1 |
| p.D791Y | THYM | 1 |
| p.P139Q | LUSC | 1 |
| p.D426Y | LUAD | 1 |
| p.A496P | BRCA | 1 |
| p.M840K | LUAD | 1 |
| p.D650N | LUSC | 1 |
| p.T1098A | COAD | 1 |
| p.G109R | KIRC | 1 |
| p.L1013I | LUAD | 1 |
| p.R67Q | UCEC | 1 |
| p.A489V | LUAD | 1 |
| p.Q539* | HNSC | 1 |
| p.Y424C | LUSC | 1 |
| p.S323L | STAD | 1 |
| p.R411W | STAD | 1 |
| p.R396Q | LUAD | 1 |
| p.N948K | LUAD | 1 |
| p.S344W | LUSC | 1 |
| p.T1056M | STAD | 1 |
| p.I423N | STAD | 1 |
| p.R1205H | SARC | 1 |
| p.S696L | UCEC | 1 |
| p.S758I | BLCA | 1 |
| p.T382K | THYM | 1 |
| p.P185S | SKCM | 1 |
| p.D112Y | UCEC | 1 |
| p.A500V | PAAD | 1 |
| p.S1183R | LUAD | 1 |
| p.E44K | SKCM | 1 |
| p.G792R | SKCM | 1 |
| p.C127S | OV | 1 |
| p.R471C | UCEC | 1 |
| p.V711M | LIHC | 1 |
| p.G109C | BLCA | 1 |
| p.R1063C | LUAD | 1 |
| p.A357T | STAD | 1 |
| p.R1179C | UCEC | 1 |
| p.T961K | LUAD | 1 |
| p.G120A | HNSC | 1 |
| p.T45I | STAD | 1 |
| p.M840I | COAD | 1 |
| p.Q560H | LUAD | 1 |
| p.E1209K | SKCM | 1 |
| p.E988K | SKCM | 1 |
| p.D549Y | LUAD | 1 |
| p.G636V | LUAD | 1 |
| p.Q505H | BRCA | 1 |
| p.Q557E | LUAD | 1 |
| p.V428I | DLBC | 1 |
| p.R889L | ESCA | 1 |
| p.K27N | DLBC | 1 |
| p.S881L | GBM | 1 |
| p.P1050L | SKCM | 1 |
| p.E969K | UCEC | 1 |
| p.S395F | SKCM | 1 |
| p.A1132S | LUAD | 1 |
| p.P408L | SKCM | 1 |
| p.G546R | SKCM | 1 |
| p.R435K | PRAD | 1 |
| p.S1058F | SKCM | 1 |
| p.Q103* | SKCM | 1 |
| p.A493T | STAD | 1 |
| p.T382M | LUAD | 1 |
| p.S1015N | HNSC | 1 |
| p.R82Q | SKCM | 1 |
| p.S152F | SKCM | 1 |
| p.G593D | GBM | 1 |
| p.R924K | SKCM | 1 |
| p.E88K | SKCM | 1 |
| p.G614V | READ | 1 |
| p.N634Y | SKCM | 1 |
| p.A715P | LUAD | 1 |
| p.R982W | UCEC | 1 |
| p.S78N | HNSC | 1 |
| p.V55F | HNSC | 1 |
| p.S1039L | SKCM | 1 |
| p.A71T | READ | 1 |
| p.A984V | UCEC | 1 |
| p.K801* | LUAD | 1 |
| p.L1083I | KIRC | 1 |
| p.M434I | SKCM | 1 |
| p.D443G | STAD | 1 |
| p.A1219D | UCEC | 1 |
| p.R889* | SKCM | 1 |
| p.S93T | LUAD | 1 |
| p.G42D | COAD | 1 |
| p.L35* | LUSC | 1 |
| p.E797* | LUAD | 1 |
| p.R713H | UCEC | 1 |
| p.R982W | PRAD | 1 |
| p.S537I | UCEC | 1 |
| p.L437I | HNSC | 1 |
| p.N714D | STAD | 1 |
| p.Q430* | SKCM | 1 |
| Top |
| TissGeneCNV for CTNND2 |
| Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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| Top |
| TissGeneFusions for CTNND2 |
| Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
| Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
| Chimerdb3.0 | ChiTaRs | NA | BI520168 | KLHDC3-CTNND2 | chr6:42989028 | chr5:11094593 | |
| Chimerdb3.0 | ChiTaRs | NA | BF992979 | EHD3-CTNND2 | chr2:31489837 | chr5:11280828 | |
| Chimerdb3.0 | FusionScan | LGG | TCGA-QH-A6XC-01A | CTNND2-NRBP1 | In-Frame | chr5:11732247 | chr2:27656539 |
| TCGAfusionPortal | PRADA | BRCA | TCGA-E9-A247-01A | CTNND2-P4HA2 | CDS-5UTR | Chr5:11903929 | Chr5:131554337 |
| TCGAfusionPortal | PRADA | BRCA | TCGA-E9-A247-01A | FAS-CTNND2 | In-frame | Chr10:90762951 | Chr5:11023091 |
| TCGAfusionPortal | PRADA | LUSC | TCGA-46-3765-01A | MTF2-CTNND2 | Out-of-frame | Chr1:93545088 | Chr5:11199773 |
| Top |
| TissGeneNet for CTNND2 |
| Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
| BRCA (tumor) | BRCA (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| COAD (tumor) | COAD (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| HNSC (tumor) | HNSC (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| KICH (tumor) | KICH (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| KIRC (tumor) | KIRC (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| KIRP (tumor) | KIRP (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| LIHC (tumor) | LIHC (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| LUAD (tumor) | LUAD (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| LUSC (tumor) | LUSC (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| PRAD (tumor) | PRAD (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| STAD (tumor) | STAD (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| THCA (tumor) | THCA (normal) |
| CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (tumor) | CTNND2, LCK, ATN1, CDH1, PSEN1, CTNNB1, FYN, CTTN, ABL1, PSEN2, NUDT21, TTR, ZBTB33, LNX1, ERBB2IP, CDH2, SPHK1, LRRC7, MAGI2, PDZD2 (normal) |
 |  |
| Top |
| TissGeneProg for CTNND2 |
| Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
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| Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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| Top |
| TissGeneClin for CTNND2 |
| TissGeneDrug for CTNND2 |
| Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
| DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Top |
| TissGeneDisease for CTNND2 |
| Disease information associated with TissGene (DisGeNet, 2016-06-01) |
| Disease ID | Disease name | # pubmeds | Source |
| umls:C0376358 | Malignant neoplasm of prostate | 7 | BeFree |
| umls:C0600139 | Prostate carcinoma | 7 | BeFree |
| umls:C0010314 | Cri-du-Chat Syndrome | 4 | BeFree,CTD_human,ORPHANET |
| umls:C0027092 | Myopia | 4 | BeFree,GAD |
| umls:C0242379 | Malignant neoplasm of lung | 4 | BeFree |
| umls:C0036341 | Schizophrenia | 3 | BeFree,GAD,LHGDN |
| umls:C0684249 | Carcinoma of lung | 3 | BeFree |
| umls:C0686619 | Secondary malignant neoplasm of lymph node | 3 | BeFree |
| umls:C0001418 | Adenocarcinoma | 2 | BeFree |
| umls:C0002395 | Alzheimer's Disease | 2 | BeFree |
| umls:C0007131 | Non-Small Cell Lung Carcinoma | 2 | BeFree |
| umls:C0025362 | Mental Retardation | 2 | BeFree |
| umls:C0027627 | Neoplasm Metastasis | 2 | BeFree |
| umls:C0033578 | Prostatic Neoplasms | 2 | LHGDN |
| umls:C0154778 | Myopia, Degenerative | 2 | BeFree,GAD |
| umls:C0271183 | Severe myopia | 2 | BeFree |
| umls:C0279626 | Squamous cell carcinoma of esophagus | 2 | BeFree |
| umls:C0596263 | Carcinogenesis | 2 | BeFree |
| umls:C3714756 | Intellectual Disability | 2 | BeFree |
| umls:C0002736 | Amyotrophic Lateral Sclerosis | 1 | GWASCAT |
| umls:C0003469 | Anxiety Disorders | 1 | BeFree |
| umls:C0004096 | Asthma | 1 | GAD |
| umls:C0004352 | Autistic Disorder | 1 | BeFree |
| umls:C0004936 | Mental disorders | 1 | BeFree |
| umls:C0005586 | Bipolar Disorder | 1 | BeFree |
| umls:C0006142 | Malignant neoplasm of breast | 1 | BeFree |
| umls:C0007112 | Adenocarcinoma of prostate | 1 | BeFree |
| umls:C0007621 | Neoplastic Cell Transformation | 1 | CTD_human |
| umls:C0009402 | Colorectal Carcinoma | 1 | BeFree |
| umls:C0017636 | Glioblastoma | 1 | CTD_human |
| umls:C0017638 | Glioma | 1 | BeFree |
| umls:C0024115 | Lung diseases | 1 | BeFree |
| umls:C0029925 | Ovarian Carcinoma | 1 | BeFree |
| umls:C0032227 | Pleural effusion disorder | 1 | BeFree |
| umls:C0036857 | Severe mental retardation (I.Q. 20-34) | 1 | BeFree |
| umls:C0040336 | Tobacco Use Disorder | 1 | GAD |
| umls:C0041696 | Unipolar Depression | 1 | BeFree |
| umls:C0152013 | Adenocarcinoma of lung (disorder) | 1 | BeFree |
| umls:C0234861 | Cri du chat | 1 | BeFree |
| umls:C0271160 | Cortical cataract | 1 | BeFree |
| umls:C0518014 | Hematocrit level | 1 | GAD |
| umls:C0678222 | Breast Carcinoma | 1 | BeFree |
| umls:C0751265 | Learning Disabilities | 1 | BeFree |
| umls:C1140680 | Malignant neoplasm of ovary | 1 | BeFree |
| umls:C1269683 | Major Depressive Disorder | 1 | BeFree |
| umls:C1392786 | Cognitive changes | 1 | BeFree |
| umls:C1510497 | Lens Opacities | 1 | BeFree |
| umls:C1510586 | Autism Spectrum Disorders | 1 | BeFree |
| umls:C1527249 | Colorectal Cancer | 1 | BeFree |
| umls:C1561955 | Fibrinogen Adverse Event | 1 | GAD |
| umls:C1704272 | Benign Prostatic Hyperplasia | 1 | BeFree |
| umls:C2239176 | Liver carcinoma | 1 | BeFree |
| umls:C3549742 | Breast cancer, lobular | 1 | BeFree |
| umls:C2931860 | Monosomy 5p | 0 | ORPHANET |
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