TissGeneSummary for ZNF100 |
Gene summary |
Basic gene information | Gene symbol | ZNF100 |
Gene name | zinc finger protein 100 | |
Synonyms | - | |
Cytomap | UCSC genome browser: 19p12 | |
Type of gene | protein-coding | |
RefGenes | NM_173531.3, | |
Description | zinc finger protein 100 (Y1) | |
Modification date | 20141207 | |
dbXrefs | MIM : 603982 | |
HGNC : HGNC | ||
Ensembl : ENSG00000197020 | ||
HPRD : 10359 | ||
Vega : OTTHUMG00000182872 | ||
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_ZNF100 | |
BioGPS: 163227 | ||
Pathway | NCI Pathway Interaction Database: ZNF100 | |
KEGG: ZNF100 | ||
REACTOME: ZNF100 | ||
Pathway Commons: ZNF100 | ||
Context | iHOP: ZNF100 | |
ligand binding site mutation search in PubMed: ZNF100 | ||
UCL Cancer Institute: ZNF100 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | ||
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of ZNF100 | ||
Description by TissGene annotations |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for ZNF100 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for ZNF100 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for ZNF100 |
TissGeneSNV for ZNF100 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.S512F | READ | 1 |
p.L74V | STAD | 1 |
p.E433Q | CESC | 1 |
p.D83Y | LUAD | 1 |
p.I505V | BLCA | 1 |
p.Q115L | HNSC | 1 |
p.A474V | LUSC | 1 |
p.D521N | LUAD | 1 |
p.E43K | STAD | 1 |
p.E43Q | STAD | 1 |
p.V314E | LUSC | 1 |
p.E230D | READ | 1 |
p.T188K | CESC | 1 |
p.I85F | STAD | 1 |
p.Y383N | KICH | 1 |
p.F205V | UCEC | 1 |
p.H339D | CESC | 1 |
p.T305I | SKCM | 1 |
p.D460E | HNSC | 1 |
p.R309T | LUSC | 1 |
p.R384L | LUAD | 1 |
p.R309I | UCEC | 1 |
p.T359A | CHOL | 1 |
p.Q222E | CESC | 1 |
p.E160K | BLCA | 1 |
p.R252K | STAD | 1 |
p.H187Y | CESC | 1 |
p.E154D | LUAD | 1 |
p.R421K | UCEC | 1 |
p.A130V | ESCA | 1 |
p.P288T | COAD | 1 |
p.K364M | UCEC | 1 |
p.H507N | KIRC | 1 |
p.R290T | LUSC | 1 |
p.G239V | LUAD | 1 |
p.G239D | CHOL | 1 |
p.R5M | UCEC | 1 |
p.D162N | CESC | 1 |
p.H367N | THYM | 1 |
p.H112Y | SKCM | 1 |
p.C322R | STAD | 1 |
p.F189Y | LUSC | 1 |
p.E129V | CHOL | 1 |
p.K324R | LUAD | 1 |
p.S527I | STAD | 1 |
p.I170V | COAD | 1 |
p.F298S | SKCM | 1 |
p.R496Q | ESCA | 1 |
p.K374Q | LUAD | 1 |
p.E488Q | BLCA | 1 |
p.R384Q | UCEC | 1 |
p.M477V | LIHC | 1 |
p.E154K | CESC | 1 |
p.L444I | LGG | 1 |
p.Q128E | CESC | 1 |
p.Q531E | BRCA | 1 |
p.E258D | UCEC | 1 |
p.S246L | SKCM | 1 |
p.F385L | CESC | 1 |
p.K420E | STAD | 1 |
p.G239C | LUAD | 1 |
p.D521N | SKCM | 1 |
p.R225I | UCEC | 1 |
p.M8I | COAD | 1 |
p.G407D | UCS | 1 |
p.K12N | STAD | 1 |
p.F400S | ESCA | 1 |
p.C215* | UCEC | 1 |
p.L540V | HNSC | 1 |
p.L217F | PAAD | 1 |
p.A465V | LIHC | 1 |
p.W536C | UCEC | 1 |
p.M8V | COAD | 1 |
p.S213L | SKCM | 1 |
p.C9Y | HNSC | 1 |
p.G323C | LUAD | 1 |
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TissGeneCNV for ZNF100 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for ZNF100 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
Chimerdb3.0 | ChiTaRs | NA | DB158037 | ZNF100-XPO1 | chr19:21913371 | chr2:61749775 | |
TCGAfusionPortal | PRADA | LUAD | TCGA-44-7669-01A | ZNF100-GIPC1 | CDS-5UTR | Chr19:21948496 | Chr19:14603724 |
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TissGeneNet for ZNF100 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for ZNF100 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for ZNF100 |
TissGeneDrug for ZNF100 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for ZNF100 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |