TissGeneSummary for OR7E24 |
Gene summary |
Basic gene information | Gene symbol | OR7E24 |
Gene name | olfactory receptor, family 7, subfamily E, member 24 | |
Synonyms | HSHT2|OR19-8|OR7E24P|OR7E24Q | |
Cytomap | UCSC genome browser: 19p13.2 | |
Type of gene | protein-coding | |
RefGenes | NM_001079935.1, | |
Description | olfactory receptor 7E24olfactory receptor OR19-14 | |
Modification date | 20141207 | |
dbXrefs | HGNC : HGNC | |
Protein | UniProt: go to UniProt's Cross Reference DB Table | |
Expression | CleanEX: HS_OR7E24 | |
BioGPS: 26648 | ||
Pathway | NCI Pathway Interaction Database: OR7E24 | |
KEGG: OR7E24 | ||
REACTOME: OR7E24 | ||
Pathway Commons: OR7E24 | ||
Context | iHOP: OR7E24 | |
ligand binding site mutation search in PubMed: OR7E24 | ||
UCL Cancer Institute: OR7E24 | ||
Assigned class in TissGDB* | C | |
Included tissue-specific gene expression resources | HPA,GTEx | |
Specific-tissues in normal samples (assigned by TissGDB using HPA, TiGER, and GTEx) | Testis | |
Cancer types related to the specific-tissues in cancer samples (assigned by TissGDB using TCGA) | TGCT | |
Reference showing the relevant tissue of OR7E24 | ||
Description by TissGene annotations | TissgsKTS CNV lost TissGeneKTS |
* Class A consists of genes with literature evidence and is part of the cTissGenes. Class B consists of only cTissGenes without additional evidence. The remaining genes belong to Class C. |
Gene ontology having evidence of Inferred from Direct Assay (IDA) from Entrez |
GO ID | GO term | PubMed ID |
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TissGeneExp for OR7E24 |
Gene expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
Gene isoform expressions across 28 cancer types (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA pan-cancer tcga_rsem_isoform_tpm, version 2016-09-01) |
Gene expressions across normal tissues of GTEx data (GTEx GTEx_Analysis_v6_RNA-seq_RNA-SeQCv1.1.8_gene_rpkm.gct) - Here, we shows the matched tissue types only among our 28 cancer types. |
Different expressions across 14 cancer types with more than 10 samples between matched tumors and normals (X-axis: cancer type and Y-axis: log2(norm_counts+1)) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) |
- Significantly differentially expressed cancer types and information. (|Fold change|>1 and FDR<0.05) |
Cancer type | Mean(exp) in tumor | Mean(exp) in matched normal | Log2FC | P-val. | FDR |
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TissGene-miRNA for OR7E24 |
Significantly anti-correlated miRNAs of TissGene across 28 cancer types (Gene-miRNA relations from TargetScanHuman Relsease 7.1, Conserved_Site_Context_Scores.txt.zip, 06.01.2016) (TCGA IlluminaHiSeq_miRNASeq, log2(RPM+1) data, version 2016-11-21) (TCGA IlluminaHiSeq_RNASeqV2, log2(normalized_count+1) data, version 2016-08-16) (Spearman’s Rank Correlation (p-value<0.05 and coefficient<-0.25)) |
Cancer type | miRNA id | miRNA accession | P-val. | Coeff. | # samples |
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TissGeneMut for OR7E24 |
TissGeneSNV for OR7E24 |
nsSNV counts per each loci. Different colors of circles represent different cancer types. Circle size denotes number of samples. (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) * Click on the image to enlarge it in a new window. |
Somatic nucleotide variants of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of mutated samples) The numbers in parentheses are numbers of samples with mutation (nsSNVs). (TCGA somatic mutation (SNPs and small INDELs) data, version 2016-04-25) |
- nsSNVs sorted by frequency. |
AAchange | Cancer type | # samples |
p.E29K | SKCM | 2 |
p.T248S | CESC | 2 |
p.X340Y | COAD | 1 |
p.M154I | KIRP | 1 |
p.H262Q | LUSC | 1 |
p.L179F | SKCM | 1 |
p.F234L | LUAD | 1 |
p.K238E | SKCM | 1 |
p.C115X | ACC | 1 |
p.P247S | CESC | 1 |
p.P334S | SKCM | 1 |
p.S134I | CESC | 1 |
p.A46S | LUAD | 1 |
p.G251R | SKCM | 1 |
p.M52V | GBM | 1 |
p.P156S | SKCM | 1 |
p.S285F | SKCM | 1 |
p.T25S | LIHC | 1 |
p.R287S | SKCM | 1 |
p.G260A | LUAD | 1 |
p.M154I | SKCM | 1 |
p.S36L | BLCA | 1 |
p.L322V | BLCA | 1 |
p.A292D | LGG | 1 |
p.D130N | SKCM | 1 |
p.C115* | ACC | 1 |
p.S193F | COAD | 1 |
p.Y296C | STAD | 1 |
p.P228S | SKCM | 1 |
p.F121L | STAD | 1 |
p.S51Y | LUAD | 1 |
p.L73I | LGG | 1 |
p.A46V | UCEC | 1 |
p.A46P | LUAD | 1 |
p.D129N | CESC | 1 |
p.D314N | SKCM | 1 |
p.L179F | THYM | 1 |
p.S309G | LUSC | 1 |
p.G90S | UCEC | 1 |
p.S69C | CESC | 1 |
p.S174Y | LUAD | 1 |
p.S200P | LIHC | 1 |
p.T105N | LUAD | 1 |
p.P76S | SKCM | 1 |
p.R151Q | STAD | 1 |
p.G47E | SKCM | 1 |
p.C186G | KIRP | 1 |
p.R157C | ESCA | 1 |
p.S2F | SKCM | 1 |
p.A143D | HNSC | 1 |
p.P156L | SKCM | 1 |
p.Y337S | COAD | 1 |
p.P247T | LUAD | 1 |
p.F306C | MESO | 1 |
p.L124V | CESC | 1 |
p.P334L | SKCM | 1 |
p.P5L | SKCM | 1 |
p.F195L | READ | 1 |
p.F11S | SKCM | 1 |
p.F125C | STAD | 1 |
p.M99I | SKCM | 1 |
p.K13* | SARC | 1 |
p.E20K | LUAD | 1 |
p.L132I | PAAD | 1 |
p.D209N | READ | 1 |
p.D139V | STAD | 1 |
p.L81F | SKCM | 1 |
p.K238T | PAAD | 1 |
p.Q104P | LUSC | 1 |
p.M128K | SARC | 1 |
p.V123A | CESC | 1 |
p.G273R | SKCM | 1 |
p.R140Q | READ | 1 |
p.P147L | SKCM | 1 |
p.G90S | SKCM | 1 |
p.Q22H | UCEC | 1 |
p.G231E | SKCM | 1 |
p.S134N | UCS | 1 |
p.E214K | SKCM | 1 |
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TissGeneCNV for OR7E24 |
Copy number variations of TissGene across 28 cancer types (X-axis: cancer type and Y-axis: % of CNV samples) (TCGA Gistic2_CopyNumber_Gistic2_all_data_by_genes, Gistic2 copy number data, version 2016-08-16) |
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TissGeneFusions for OR7E24 |
Fusion genes including TissGene (ChimerDB 3.0, 2016-12-01 and TCGA fusion Portal 2015-12-01) |
Database | Src | Cancer type | Sample | Fusion gene | ORF | 5'-gene BP | 3'-gene BP |
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TissGeneNet for OR7E24 |
Co-expressed gene networks based on protein-protein interaction data (CePIN) (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (PINA2 ppi data) |
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TissGeneProg for OR7E24 |
Kaplan-Meier plots with logrank tests of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image to enlarge it in a new window. |
Kaplan-Meier plots with logrank test of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of overall survival (OS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
Forest plot of Cox proportional hazard ratio (HR) and 95% CI of relapse free survival (RFS) using 28 cancer types (TCGA IlluminaHiSeq_RNASeqV2, pan-cancer normalized log2(norm_counts+1) data, version 2016-08-16) (TCGA clinicalMatrix, phenotype data, version 2016-04-27) * Click on the image enlarge it in a new window. |
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TissGeneClin for OR7E24 |
TissGeneDrug for OR7E24 |
Drug information targeting TissGene (DrugBank Version 5.0.6, 2017-04-01) |
DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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TissGeneDisease for OR7E24 |
Disease information associated with TissGene (DisGeNet, 2016-06-01) |
Disease ID | Disease name | # pubmeds | Source |